Cefmetazole
- Product Name
- Cefmetazole
- CAS No.
- 56796-20-4
- Chemical Name
- Cefmetazole
- Synonyms
- cs1170;(6r;CMZ;U 72791;U 72791a;SKF 83088;Cefatrixine;Cefmetazole;Cefmetazolo;Cefmetazolum
- CBNumber
- CB9231320
- Molecular Formula
- C15H17N7O5S3
- Formula Weight
- 471.53
- MOL File
- 56796-20-4.mol
Cefmetazole Property
- Melting point:
- 163-165?C
- Density
- 1.4380 (rough estimate)
- refractive index
- 1.7400 (estimate)
- storage temp.
- 2-8°C
- solubility
- Methanol (Slightly, Heated)
- pka
- 2.65±0.50(Predicted)
- form
- Solid
- color
- White
- Water Solubility
- Soluble in water
- CAS DataBase Reference
- 56796-20-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-42/43
- Safety Statements
- 26-36
- WGK Germany
- 2
- RTECS
- XI0372200
- HS Code
- 2941906000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P284Wear respiratory protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 1097782
- Product name
- Cefmetazole
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200MG
- Price
- $420
- Updated
- 2024/03/01
- Product number
- J66791
- Product name
- Cefmetazole
- Packaging
- 5g
- Price
- $406
- Updated
- 2024/03/01
- Product number
- J66791
- Product name
- Cefmetazole
- Packaging
- 1g
- Price
- $89.1
- Updated
- 2021/12/16
- Product number
- 30269
- Product name
- Cefmetazole
- Packaging
- 10mg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 30269
- Product name
- Cefmetazole
- Packaging
- 100mg
- Price
- $961
- Updated
- 2024/03/01
Cefmetazole Chemical Properties,Usage,Production
Description
Cefmetazole is a cephamycin with a nonaromatic side chain at C-7. In addition to a fairly characteristic second-generation cephalosporin antimicrobial spectrum, it possess fairly significant anti-antiaerobic activity. The ejection of its C-3 side chain leads to alcohol intolerance of the disulfuram type and prolonged clotting times.
General Description
Cefmetazole was synthesized by Sankyo Co. in 1976starting with a biosynthetic cephamycin. It shows excellent activity against Serratia and Proteus, against which cefazolin is not active, and it has stronger activity than cefoxitin, another derivative of cephamycin. Cefmetazole is active against anaerobes and resistant to β-lactamase, but it is not active against Pseudomonas aeruginosa.
Chemical Properties
White Solid
Uses
Semi-synthetic antibiotic derived from Cephamycin. Antibacterial.
Uses
A broad spectrum second generation cephalosporin antibiotic
Definition
ChEBI: A cephalosporin antibiotic containg an N1-methyltetrazol-5-ylthiomethyl side-chain at C-3 of the parent cephem bicyclic structure.
Antimicrobial activity
It is active
against Pr. mirabilis, Pr. vulgaris, Morganella morganii, Yersinia spp.and most anaerobes. S. marcescens is moderately susceptible,
but Ps. aeruginosa and E. faecalis are resistant. It is active against
Mycobacterium fortuitum and some strains of M. chelonei. It is
resistant to a wide range of β-lactamases.
The serum concentration at the end of a 1 g intravenous
infusion is around 77 mg/L. Plasma protein binding is 68%. It
is principally excreted in the urine with a plasma half-life of c.
1.3 h; 70% is recovered over the first 6 h. In patients whose
creatinine clearance is less than 10 mL/min, plasma levels are
elevated and the plasma half-life is increased to around 15 h.
Side effects associated with the methylthiotetrazole group
at position C-3 have been reported. Uses are similar to those
of cefoxitin, but it is not widely available.
Cefmetazole Preparation Products And Raw materials
Raw materials
Preparation Products
Cefmetazole Suppliers
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View Lastest Price from Cefmetazole manufacturers
- Product
- Cefmetazole 56796-20-4
- Price
- US $0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99%
- Supply Ability
- 10kg
- Release date
- 2024-04-09
- Product
- Cefmetazole 56796-20-4
- Price
- US $0.00/Kg/Bag
- Min. Order
- 1KG
- Purity
- 97.5%min
- Supply Ability
- 100KG
- Release date
- 2021-06-08
- Product
- Cefmetazole 56796-20-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-09-01