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Cefmetazole sodium

Product Name
Cefmetazole sodium
CAS No.
56796-39-5
Chemical Name
Cefmetazole sodium
Synonyms
C08104;Metafar;Cefmetazone;Cefmetazole-Na;Sodium cefmetazole;Cefmetazole sodium;CS-1170 sodium salt;Cefotetan Impurity 2;Cefmetazole Sodium Salt >Cefmetazole sodium USP/EP/BP
CBNumber
CB2231321
Molecular Formula
C15H18N7NaO5S3
Formula Weight
495.52
MOL File
56796-39-5.mol
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Cefmetazole sodium Property

Melting point:
>130°C (dec.)
storage temp. 
Inert atmosphere,2-8°C
solubility 
H2O: soluble50mg/mL
form 
powder
color 
White to Off-White
Water Solubility 
Soluble in water
Sensitive 
Hygroscopic
Merck 
14,1926
Stability:
Hygroscopic
InChIKey
BITQGIOJQWZUPL-PBCQUBLHSA-M
CAS DataBase Reference
56796-39-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-42/43
Safety Statements 
26-36
WGK Germany 
2
RTECS 
XI0372200
HS Code 
2941.90.3000
Toxicity
LD50 i.v. in rats: >5000 mg/kg (Masuda)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C6048
Product name
Cefmetazole sodium salt
Packaging
1g
Price
$128
Updated
2024/03/01
Sigma-Aldrich
Product number
C6048
Product name
Cefmetazole sodium salt
Packaging
250mg
Price
$43
Updated
2023/06/20
TCI Chemical
Product number
C3029
Product name
Cefmetazole Sodium Salt
Purity
>97.0%(T)
Packaging
250mg
Price
$67
Updated
2024/03/01
TCI Chemical
Product number
C3029
Product name
Cefmetazole Sodium Salt
Purity
>97.0%(T)
Packaging
1g
Price
$237
Updated
2024/03/01
Alfa Aesar
Product number
J66348
Product name
Cefmetazole sodium, 921 μg/mg
Packaging
1g
Price
$87.65
Updated
2024/03/01
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Cefmetazole sodium Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Semi-synthetic antibiotic derived from Cephamycin. Antibacterial

Uses

Cefmetazole sodium is used clinically in combination with Tanreqing for the treatment of Pulmonary infections like Senile Emphysema and other acute bacterial infections.

Definition

ChEBI: An organic sodium salt that is the sodium salt of cefmetazole.

brand name

Zefazone (Pharmacia & Upjohn).

Clinical Use

Cefmetazole (Zefazone) is a semisynthetic, third-generation,parenteral cephalosporin of the cephamycin group. Likeother cephamycins, the presence of the 7α-methoxyl groupconfers resistance to many β-lactamases. Cefmetazoleexhibits significantly higher potency against members ofthe Enterobacteriaceae family but lower activity againstBacteroides spp. than cefoxitin. It is highly active againstN. gonorrhoeae, including -lactamase–producing strains. Incommon with other cephamycins, cefmetazole is ineffectiveagainst indole-positive Proteus, Enterobacter, Providencia,Serratia, and Pseudomonas spp. Cefmetazole has the MTTmoiety associated with increased bleeding in certain highriskpatients. It has a plasma half-life of 1.1 hours.

Cefmetazole sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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Cefmetazole sodium Suppliers

Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4552
Advantage
62
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2871
Advantage
58
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
UHN Shanghai Research & Development Co., Ltd.
Tel
021-58958002 18930822973
Fax
+86 (21) 5895-8628
Email
SALES@UHNSHANGHAI.COM
Country
China
ProdList
977
Advantage
58
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View Lastest Price from Cefmetazole sodium manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Cefmetazole sodium 56796-39-5
Price
US $0.00/KG/Tin
Min. Order
5KG
Purity
98%min
Supply Ability
500kg
Release date
2021-11-02
Hebei Weibang Biotechnology Co., Ltd
Product
Cefmetazole sodium 56796-39-5
Price
US $1.00/PCS
Min. Order
1PCS
Purity
99%
Supply Ability
10 mt
Release date
2024-10-31
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Cefmetazole sodium 56796-39-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-04-11

56796-39-5, Cefmetazole sodiumRelated Search:


  • Cefmetazone
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7S)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R-cis)-
  • Cefmetazole-Na
  • CS-1170 sodium salt
  • Metafar
  • Sodium cefmetazole
  • (6R,7S)-7-[[2-[(Cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl -1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene -2-carboxylic Acid Sodium Salt
  • Cefmetazole sodium
  • Sodium (6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • Cefotetan Impurity 1 Sodium Salt (Cefmetazole Sodium Salt)
  • sodium (6R,7S)-7-(2-((cyanomethyl)thio)acetamido
  • sodium (6R,7S)-7-[[2-(cyanomethylthio)-1-oxoethyl]amino]-7-methoxy-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • (6R)-7-[[[(Cyanomethyl)thio]acetyl]amino]-7β-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt
  • C08104
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[2-[(cyanoMethyl)thio]acetyl]aMino]-7-Methoxy-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-,sodiuM salt (1:1), (6R,7S)-
  • Cefotetan Impurity 2
  • Cefmetazole Sodium Salt &gt
  • Cefmetazole sodium USP/EP/BP
  • Sodium (6R,7S)-7-(2-((cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • 56796-39-5
  • 59796-39-5
  • C15H16N7NaO5S3
  • C15H17N7O5S3
  • C15H16N7O5S3Na
  • Sulfur & Selenium Compounds
  • A - KAntibiotics
  • Antibacterial
  • Antibiotics A to
  • Antibiotics A-FAntibiotics
  • Chemical Structure Class
  • Interferes with Cell Wall SynthesisAntibiotics
  • Mechanism of Action
  • Penicillins and Cephalosporins (beta-Lactams)
  • Spectrum of Activity
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals