Rebaudioside D

Product Name: Rebaudioside D
CAS No.: 63279-13-0
Chemical Name: Rebaudioside D
Synonyms: Rebaudin D;Rebaudioside D;REBAUDIOSIDE C(P);Rebaudioside D-RM;Rebaudioside D(RD);Leibaodi glycoside D;Rebaudioside D (100 mg);Steviol Glycosides Reb D;Sweeteners Rebaudioside D;Kaur-16-en-18-oic acid,13-[(O-b-D-glucopyranosyl-(1?2)-...
CBNumber: CB22334765
Molecular Formula: C50H80O28
Formula Weight: 1129.16
MOL File: 63279-13-0.mol

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Rebaudioside D Property

Melting point:: >243°C (dec.)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form: Solid
color: White to Off-White
InChIKey: RPYRMTHVSUWHSV-CUZJHZIBSA-N
LogP: -3.377 (est)

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 19189
Product name: Rebaudioside D
Purity: analytical standard
Packaging: 10mg
Price: $1320
Updated: 2022/05/15

Cayman Chemical

Product number: 27880
Product name: Rebaudioside D
Packaging: 1mg
Price: $61
Updated: 2024/03/01

Cayman Chemical

Product number: 27880
Product name: Rebaudioside D
Packaging: 25mg
Price: $1019
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL82398
Product name: Rebaudioside D
Purity: phyproof Reference Substance
Packaging: 10mg
Price: $802
Updated: 2024/03/01

Cayman Chemical

Product number: 27880
Product name: Rebaudioside D
Packaging: 5mg
Price: $264
Updated: 2024/03/01

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Rebaudioside D Chemical Properties,Usage,Production

Description

Rebaudioside D, a glycoside of the diterpene steviol is a minor constituent found in leaves of Stevia rebaudiana. It is considered non-caloric and is about 200–220 times sweeter than sucrose.
Rebaudioside D is a natural non-caloric sweetener. It is a steviol glycoside that has been found in S. rebaudiana leaves. Rebaudioside D, similarly to rebaudioside A and rebaudioside C, is metabolized by gut microbiota to steviol, a compound whose safety is widely studied.

Uses

Rebaudioside D is a steviol glycoside used as a nutritive sweetener and may be used as a replacement for sugar in foods and beverages. Useful in the treatment of blood glucose sensitive diseases such as diabetes, high blood pressure, and obesity.
It may be used as internal standard to optimize the desorption electrospray ionization (DESI) mass spectrometry during the analysis of Stevia leaves for diterpene glycosides.

Definition

ChEBI: Rebaudioside D is a rebaudioside that is rebaudioside A in which the hydroxy group at position 2 of the beta-D-glucosyl ester moiety has been converted to the corresponding beta-D-glucoside. Found in minute quantities in the leaves of Stevia rebaudiana. It has a role as a sweetening agent. It is a tetracyclic diterpenoid, a rebaudioside and a sophoroside. It is functionally related to a rebaudioside A, a rebaudioside E and a beta-D-Glcp-(1->2)-[beta-D-Glcp-(1->3)]-beta-D-Glcp.

Preparation

The rebaudioside D-rich steviol glycoside preparation (~95% rebaudioside D) is produced via an enzymatic conversion process using a strain of Pichia pastoris that has been genetically modified to express UDPglucosyltransferase EUGTll. In the first stage of manufacturing, a steviol glycoside primary extract from the leaves of 5. rebaudiana Bertoni containing 55±5% of rebaudioside A is produced according to the methodology outlined in the Chemical and Technical Assessment (CTA) published by the Food and Agriculture Organization (FAO)/JECFA for steviol glycosides (FAQ, 2016). In the next step, the steviol glycoside primary extract is further purified to a purity of ~95% rebaudioside A through crystallization, also consistent with the CTA methodology. In the third stage, the P. pastoris production strain is subjected to a fermentation step to express the UGT-glucosyltransferase EUGTll, which is used to catalyze the conversion of the high-purity rebaudioside A extracted from 5. rebaudiana Bertoni to rebaudioside D. In the last stage, the rebaudioside D solution is purified and concentrated according to the methodology described in the steviol glycoside CTA, yielding a final product that contains ~95% rebaudioside D.
www.fda.gov

Rebaudioside D Preparation Products And Raw materials

Raw materials

Preparation Products

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Rebaudioside D Suppliers

China 168 India 1 United Kingdom 1 United States 13 USA 1 Global 184

ALB Technology Limited

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EMMX Biotechnology LLC

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TargetMol Chemicals Inc.

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BOC Sciences

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Aladdin Scientific

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TargetMol Chemicals Inc.

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Riedel-de Haen AG

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View Lastest Price from Rebaudioside D manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Rebaudioside D 63279-13-0
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2000ton
Release date: 2023-12-05

Shanghai Standard Technology Co., Ltd.

Product: Rebaudioside D 63279-13-0
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-05-22

Wuhan ShuEr Biology Technology Co.,Ltd

Product: Sweeteners Rebaudioside D 63279-13-0
Price: US $2.00/kg
Min. Order: 1kg
Purity: 98
Supply Ability: 200kg
Release date: 2022-09-22

63279-13-0, Rebaudioside DRelated Search:

REBAUDIOSIDE F(P) Rebaudioside J Rebaudioside E Rebaudioside G Rebaudioside I Sucralose Acesulfame REBAUDIOSIDE B(P)(NEW) Rebaudioside A RebaudiosideC Rebaudioside M REBAUDIOSIDE A(RG) REBAUDIOSIDE B(P) RUBUSOSIDE Steviol glucosilsteviol Rebaudioside D kaurenoic acid

(4R)-13-[[2-O-(β-D-Glucopyranosyl)-3-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl]oxy]kaur-16-en-18-oic acid 2-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl ester

Rebaudioside D

REBAUDIOSIDE C(P)

(4alpha)-13-[(O-beta-D-Glucopyranosyl-(1-2)-O-[beta-D-glucopyranosyl-(1-3)]-beta-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid 2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl ester

(4α)-13-[(O-β-D-Glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl)oxy]kaur-16-en-18-oic acid 2-O-β-D-glucopyranosyl-β-D-glucopyranosyl ester

Rebaudioside D (100 mg)

Kaur-16-en-18-oic acid,13-[(O-b-D-glucopyranosyl-(12)-O-[b-D-glucopyranosyl-(13)]-b-D-glucopyranosyl)oxy]-, 2-O-b-D-glucopyranosyl-b-D-glucopyranosyl ester, (4a)-

(4R)-13-[[2-O-(β-D-Glucopyranosyl)-3-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl]oxy]kaur-16-en-18-oic acid 2-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl ester USP/EP/BP

Rebaudioside D(RD)

Kaur-16-en-18-oic acid,13-[(O-b-D-glucopyranosyl-(1?2)-...

(4R)-13-[[2-O-(β-D-Glucopyranosyl)-3-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl]oxy]kaur-16-en-18-oic acid 2-O-(β-D-glucopyranosyl)-β-D-glucopyranosyl ester

Sweeteners Rebaudioside D

(4R)-13-[[2-O-(b-D-Glucopyranosyl)-3-O-(b-D-glucopyranosyl)-b-D-glucopyranosyl]oxy]kaur-16-en-18-oic acid 2-O-(b-D-glucopyranosyl)-b-D-glucopyranosyl ester

(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl (4R,4aS,6aR,9S,11aR,11bS)-9-(((2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylate

Leibaodi glycoside D

Steviol Glycosides Reb D

Rebaudin D

Rebaudioside D-RM

63279-13-0

C50H80O28

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract