Molsidomine
- Product Name
- Molsidomine
- CAS No.
- 25717-80-0
- Chemical Name
- Molsidomine
- Synonyms
- SIN-10;Coruno;morial;CAS 276;CORVATON;corvasal;Corraton;MOTAZOMIN;SydnopharM;molsidolat
- CBNumber
- CB2234645
- Molecular Formula
- C9H14N4O4
- Formula Weight
- 242.23
- MOL File
- 25717-80-0.mol
Molsidomine Property
- Melting point:
- 140-141°C
- Boiling point:
- 385.05°C (rough estimate)
- Density
- 1.3186 (rough estimate)
- refractive index
- 1.6300 (estimate)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Sparingly soluble in water, soluble in anhydrous ethanol and in methylene chloride.
- pka
- pK (100°) 3.0 ± 0.1
- form
- Solid
- color
- White to Off-White
- λmax
- 317nm(MeOH)(lit.)
- Merck
- 14,6234
- CAS DataBase Reference
- 25717-80-0(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- M2901
- Product name
- Molsidomine
- Packaging
- 500mg
- Price
- $91.1
- Updated
- 2023/01/07
- Product number
- M2901
- Product name
- Molsidomine
- Packaging
- 5g
- Price
- $522
- Updated
- 2023/01/07
- Product number
- M2524
- Product name
- Molsidomine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $48
- Updated
- 2024/03/01
- Product number
- M2524
- Product name
- Molsidomine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $141
- Updated
- 2024/03/01
- Product number
- Y0000821
- Product name
- Molsidomine
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- y0000821
- Price
- $150
- Updated
- 2024/03/01
Molsidomine Chemical Properties,Usage,Production
Chemical Properties
White to Off-White Solid
Originator
Corvasal,Hoechst
Uses
Molsidomine is an antianginal agent. Molsidomine is an effective therapeutic agents in the treatment of angina pectoris. Molsidomine is a sydnonimine derivative that acts as a heterocyclic direct nitric oxide donor.
Definition
ChEBI: 1-ethoxy-N-[3-(4-morpholinyl)-5-oxadiazol-3-iumyl]methanimidate is a member of morpholines.
Manufacturing Process
1.6 parts by volume of ethyl chloroformate is stirred dropwise into a suspension of 1.0 part by weight of 3-morpholinosydnonimine hydrochloride in 5 parts by volume of pyridine, and the mixture is agitated for a while to allow reaction to take place. Pyridine is removed from the reaction mixture by evaporation, and the residue is dissolved in a small amount of water and extracted with chloroform several times. The extract is dehydrated by adding anhydrous magnesium sulfate and subjected to filtration. Chloroform is removed from the filtrate by distillation, crude crystals being obtained. Recrystallization of the crude crystals from toluene gives 0.6 part by weight of 3-morpholino-N-carboethoxysydnonimine having a melting point of 140°- 141°C. Yield 51%.
brand name
Corvaton (Hoechst-Roussel).
Therapeutic Function
Coronary vasodilator
Molsidomine Preparation Products And Raw materials
Raw materials
Preparation Products
Molsidomine Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from Molsidomine manufacturers
- Product
- molsidomine 25717-80-0
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.9%
- Supply Ability
- 200tons
- Release date
- 2024-04-09
- Product
- Molsidomine 25717-80-0
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-28
- Product
- Molsidomine 25717-80-0
- Price
- US $10.00-1.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-09-14