ChemicalBook > CAS DataBase List > 2-(7-Methoxynaphthalen-1-yl)acetic acid

2-(7-Methoxynaphthalen-1-yl)acetic acid

Product Name
2-(7-Methoxynaphthalen-1-yl)acetic acid
CAS No.
6836-22-2
Chemical Name
2-(7-Methoxynaphthalen-1-yl)acetic acid
Synonyms
7-Methyl-1-naphthyl acetic acid;(7-Methoxy-1-naphthyl)acetic acid;7-Methoxy-1-napthalene acetic acid;7-Methoxy-1-naphthaleneacetic acid;2-(7-Methoxy-1-naphthyl)acetic Acid;1-Naphthaleneacetic acid, 7-Methoxy-;2-(7-Methoxynaphthalen-1-yl)AceticAci;2-(7-Methoxyphthalen-1-yl)acetic acid;2-(7-Methoxynaphthalen-1-yl)acetic acid;7-Methoxy-1-naphthaleneacetic acid, 10 mM in DMSO
CBNumber
CB22462143
Molecular Formula
C13H12O3
Formula Weight
216.23
MOL File
6836-22-2.mol
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2-(7-Methoxynaphthalen-1-yl)acetic acid Property

Melting point:
153-154 ºC
Boiling point:
408.8±20.0 °C(Predicted)
Density 
1.235
storage temp. 
Sealed in dry,Room Temperature
solubility 
Dichloromethane (Slightly), Methanol (Slightly)
form 
Solid
pka
4.33±0.30(Predicted)
color 
White to Off-White
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2888
Product name
7-Methoxy-1-naphthaleneacetic Acid
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$93
Updated
2025/07/31
TCI Chemical
Product number
M2888
Product name
7-Methoxy-1-naphthaleneacetic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$279
Updated
2025/07/31
TRC
Product number
M265788
Product name
2-(7-Methoxynaphthalen-1-yl)aceticAcid
Packaging
500mg
Price
$75
Updated
2021/12/16
AK Scientific
Product number
B669
Product name
7-Methoxy-1-naphthaleneacetic Acid
Packaging
5g
Price
$61
Updated
2021/12/16
SynQuest Laboratories
Product number
2621-1-61
Product name
2-(7-Methoxynaphthalen-1-yl)acetic acid
Packaging
1g
Price
$232
Updated
2021/12/16
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2-(7-Methoxynaphthalen-1-yl)acetic acid Chemical Properties,Usage,Production

Uses

7-Methyl-1-naphthyl acetic acid is a potent inhibitor of auxin action in plants. 7-Methyl-1-naphthyl acetic acid inhibits AUX1, PIN, and ABCB protein-mediated auxin transport expressed in yeast. 7-Methyl-1-naphthyl acetic acid can be used in auxin dependent development [1].

Synthesis

6836-21-1

6836-22-2

Step 3 Synthesis of (7-methoxy-1-naphthyl)acetic acid: To a solution of methanol (12 mL) containing ethyl 7-methoxy-1-naphthylacetate (2.38 g, 9.8 mmol), sodium hydroxide (0.62 g, 15.6 mmol) and water (6 mL) were added. The reaction mixture was heated at 40°C for about 2 hours with continuous stirring. Upon completion of the reaction, the mixture was concentrated under reduced pressure and the residue was diluted with 50 mL of water and extracted with ether (4 x 25 mL). The aqueous phase was acidified with concentrated hydrochloric acid to pH=2. After conventional extraction and post-treatment, the title compound 7-methoxy-1-naphthaleneacetic acid was obtained as an off-white solid (1.9 g, 90% yield). The product was confirmed by 1H NMR (300 MHz, CD3OD): δ 3.9 (s, 3H), 4.03 (s, 2H), 7.15 (dd, J = 9.0, 2.4 Hz, 1H), 7.27-7.41 (m, 4H), 7.76 (m, 2H); LC-MS showed the molecular ion peak as 215 (M + H)+.

References

[1] Tsuda E, et al. Alkoxy-auxins are selective inhibitors of auxin transport mediated by PIN, ABCB, and AUX1 transporters. J Biol Chem. 2011 Jan 21;286(3):2354-64. DOI:10.1074/jbc.M110.171165

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Raw materials

Preparation Products

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View Lastest Price from 2-(7-Methoxynaphthalen-1-yl)acetic acid manufacturers

Career Henan Chemical Co
Product
2-(7-Methoxynaphthalen-1-yl)acetic acid 6836-22-2
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-09

6836-22-2, 2-(7-Methoxynaphthalen-1-yl)acetic acidRelated Search:

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  • 2-(7-Methoxynaphthalen-1-yl)acetic acid
  • 7-Methoxy-1-naphthaleneacetic acid
  • 7-Methoxy-1-napthalene acetic acid
  • 1-Naphthaleneacetic acid, 7-Methoxy-
  • (7-Methoxy-1-naphthyl)acetic acid
  • 2-(7-Methoxyphthalen-1-yl)acetic acid
  • 2-(7-Methoxy-1-naphthyl)acetic Acid
  • 2-(7-Methoxynaphthalen-1-yl)AceticAci
  • 7Methoxy1naphthaleneacetic acid,7 Methoxy 1 naphthaleneacetic acid
  • 7-Methyl-1-naphthyl acetic acid
  • 7-Methoxy-1-naphthaleneacetic acid, 10 mM in DMSO
  • 6836-22-2
  • Agomelatine intermediate
  • Indazoles