1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE

Product Name: 1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE
CAS No.: 76697-50-2
Chemical Name: 1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE
Synonyms: 2-(isopropylsulfonyl)a;2-propan-2-ylsulfonylaniline;2-(isopropylsulfonyl)aniline;2-(Isopropylsulphonyl)aniline;2-(propane-2-sulfonyl)aniline;2-AMinophenyl Isopropyl Sulfone;2-(isopropylsulfonyl)benzenaMine;2-(Isopropylsulphonyl)aniline 98%;2-(Propane-2-sulfonyl)-phenylaMine;1-Amino-2-(isopropylsulfonyl)benzene
CBNumber: CB2727345
Molecular Formula: C9H13NO2S
Formula Weight: 199.27
MOL File: 76697-50-2.mol

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1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE Property

Melting point:: 83.0 to 87.0 °C
Boiling point:: 381.1±34.0 °C(Predicted)
Density: 1.194±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: solid
pka: -0.79±0.10(Predicted)
color: Beige
InChI: InChI=1S/C9H13NO2S/c1-7(2)13(11,12)9-6-4-3-5-8(9)10/h3-7H,10H2,1-2H3
InChIKey: GMLAMRMKROYXNZ-UHFFFAOYSA-N
SMILES: C1(N)=CC=CC=C1S(C(C)C)(=O)=O

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Safety

Hazard Codes: Xi
Hazard Note: Irritant
HS Code: 2930909899

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: I1033
Product name: 2-(Isopropylsulfonyl)aniline
Purity: >98.0%(GC)
Packaging: 1g
Price: $47
Updated: 2025/07/31

TCI Chemical

Product number: I1033
Product name: 2-(Isopropylsulfonyl)aniline
Purity: >98.0%(GC)
Packaging: 5g
Price: $142
Updated: 2025/07/31

TRC

Product number: A611880
Product name: 2-AminophenylIsopropylSulfone
Packaging: 1g
Price: $120
Updated: 2021/12/16

Usbiological

Product number: 159401
Product name: 2-Aminophenyl Isopropyl Sulfone
Packaging: 1g
Price: $403
Updated: 2021/12/16

TRC

Product number: A611880
Product name: 2-AminophenylIsopropylSulfone
Packaging: 5g
Price: $415
Updated: 2021/12/16

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1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE Chemical Properties,Usage,Production

Uses

2-Aminophenyl Isopropyl Sulfone is a reagent used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment.

Synthesis

70415-86-0

76697-50-2

Step 3: Preparation of 2-(isopropylsulfonyl)aniline (4); 1-(isopropylsulfonyl)-2-nitrobenzene (3, 2 g, 8.73 mmol) was dissolved in methanol (25 ml) to form a homogeneous mixture. 10% palladium carbon (200 mg, 10 mol%) was added to the mixture and the reaction mixture was stirred under hydrogen atmosphere for 6 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) to confirm the complete conversion of feedstock 3 to product 4. Upon completion of the reaction, the mixture was filtered through diatomaceous earth, and the filtrate was concentrated under reduced pressure to afford 2-(isopropylsulfonyl)aniline (4, 1.73 g, quantitative yield).' HNMR (CDCl3): δ 7.66-7.62 (d, 1H), 7.40-7.30 (t, 1H), 6.85-6.78 (t, 1H), 6.73-6.70 (d, 1H), 5.10 (br s, 1H), 3.40-3.30 (m, 1H), 1.30 (s, 6H).

References

[1] Patent: WO2011/140338, 2011, A1. Location in patent: Page/Page column 46-47
[2] Patent: CN106854200, 2017, A. Location in patent: Paragraph 0064
[3] Patent: CN106146468, 2016, A. Location in patent: Paragraph 0088; 0101; 0102
[4] Patent: CN106336382, 2017, A. Location in patent: Paragraph 0099; 0141; 0142; 0143
[5] Patent: US2018/57457, 2018, A1. Location in patent: Paragraph 0260; 0262

1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE Suppliers

Americas 1 China 183 China Hong Kong 1 Czech Republic 1 Europe 1 Germany 1 India 10 Japan 2 United Kingdom 6 United States 18 Global 224

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View Lastest Price from 1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE manufacturers

Nanjing Fred Technology Co., Ltd

Product: 2-(Isopropylsulfonyl)aniline 76697-50-2
Price: US $0.00-0.00/kg
Min. Order: 0.1kg
Purity: 99%(HPLC)
Supply Ability: 5000kg/Year
Release date: 2023-12-14

Guangzhou Sunton Biotechnology Co., Ltd.

Product: 2-(isopropyl sulfonyl) aniline 7669-50-2
Price: US $48.00-40.00/KG
Min. Order: 10公斤
Purity: 99%
Supply Ability: 200tons
Release date: 2021-06-04

Career Henan Chemical Co

Product: 1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE 76697-50-2
Price: US $100.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-07-26

76697-50-2, 1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENERelated Search:

β-Caryophyllene Furosemide 2-(7-Methoxynaphthalen-1-yl)acetic acid 2-bromo-3,5-dichlorobenzenamine 1,3-Dimethoxy-2-propanol Dimethyl acetylsuccinate tert-butyl 4-(4-aMino-5-isopropoxy-2-Methylphenyl)piperidine-1-carboxylate 4-(5-isopropoxy-2-Methyl-4-nitrophenyl)pyridine Ceritinib (LDK378) 1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene LDK-378 dihydrochloride 4-Pyrimidinamine, 2,5-dichloro-N-[2-[(1-methylethyl)sulfonyl]phenyl]- 1-broMo-5-fluoro-2-Methyl-4-nitrobenzene 2,4,5-Trichloropyrimidine 1-BroMo-5-isopropoxy-2-Methyl-4-nitrobenzene 5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2) 1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE CIVENTICHEM CV-624

1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE

1-Amino-2-(isopropylsulfonyl)benzene

2-(Isopropylsulphonyl)aniline

2-(Isopropylsulphonyl)aniline 98%

2-(isopropylsulfonyl)aniline

2-(isopropylsulfonyl)benzenaMine

2-(Propane-2-sulfonyl)-phenylaMine

2-(Isopropylsulphonyl)aniline 1-Amino-2-(isopropylsulfonyl)benzene

Benzenamine, 2-[(1-methylethyl)sulfonyl]-

2-propan-2-ylsulfonylaniline

2-(isopropylsulfonyl)a

2-AMinophenyl Isopropyl Sulfone

2-(propane-2-sulfonyl)aniline

Ceritinib 2-Aminophenyl Isopropyl Sulfone

2(1H)-Pyridinone,5,6-dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-2-piperidinyl)phenyl]-

2-[(1-Methylethyl)sulfonyl]-benzenamine

1-amino-2-(isoproylsulphonyl)benzene

76697-50-2

7669-50-2