ChemicalBook > CAS DataBase List > 5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2)

5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2)

Product Name
5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2)
CAS No.
1380575-45-0
Chemical Name
5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2)
Synonyms
CR-14;LDK378 intermediate;Intermediate Impurity 31;Intermediate Impurity 32;5-Methyl-2-(1-Methylethoxy)-4-;2-Isopropoxy-5-methyl-4-(4-piperidyl)aniline Dihydrochloride;2-isopropoxy-5-methyl-4-(piperidin-4-yl)aniline hydrochloride;2-isopropoxy-5-methyl-4-(piperdin-4-yl) aniline dihydrochloride;2-isopropoxy-5-Methyl-4-(piperidin-4-yl)aniline dihydrochloride;5-Methyl-2-(1-Methylethoxy)-4-(4-piperidinyl)-Benzenamine hy...
CBNumber
CB02710521
Molecular Formula
C15H25ClN2O
Formula Weight
284.83
MOL File
1380575-45-0.mol
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5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2) Property

storage temp. 
Sealed in dry,Room Temperature
Appearance
White to off-white Solid
InChI
InChI=1S/C15H24N2O.ClH/c1-10(2)18-15-9-13(11(3)8-14(15)16)12-4-6-17-7-5-12;/h8-10,12,17H,4-7,16H2,1-3H3;1H
InChIKey
MUIYMJXNFJYXFP-UHFFFAOYSA-N
SMILES
CC1=CC(N)=C(OC(C)C)C=C1C1CCNCC1.Cl
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M304840
Product name
(1-Methylethoxy)-4-(4-piperidinyl)-BenzenaMinehydrochloride(1:2)
Packaging
100mg
Price
$60
Updated
2021/12/16
Ambeed
Product number
A329981
Product name
2-Isopropoxy-5-methyl-4-(piperidin-4-yl)anilinedihydrochloride
Purity
98%
Packaging
5g
Price
$144
Updated
2021/12/16
Chemenu
Product number
CM180657
Product name
2-isopropoxy-5-methyl-4-(piperidin-4-yl)anilinedihydrochloride
Purity
95+%
Packaging
1g
Price
$153
Updated
2021/12/16
Chemenu
Product number
CM180657
Product name
2-isopropoxy-5-methyl-4-(piperidin-4-yl)anilinedihydrochloride
Purity
95+%
Packaging
5g
Price
$299
Updated
2021/12/16
Crysdot
Product number
CD11268365
Product name
2-Isopropoxy-5-methyl-4-(piperidin-4-yl)anilinedihydrochloride
Purity
97%
Packaging
5g
Price
$317
Updated
2021/12/16
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5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2) Chemical Properties,Usage,Production

Uses

5-Methyl-2-(1-Methylethoxy)-4-(4-piperidinyl)- BenzenaMine hydrochloride (1:2) is a chemical intermediate for the preparation of ceritinib.

Application

5-Methyl-2-(1-Methylethoxy)-4-(4-piperidinyl)- BenzenaMine hydrochloride (1:2) is a chemical intermediate, also known as (4-(5-isopropoxy) -2-Methyl-4-amino-phenyl)-piperidine hydrochloride can be used in laboratory R&D synthesis process and chemical biological R&D process, and is an intermediate for the preparation of ceritinib.

Preparation

First use methanol to react with 4-(5-isopropoxy-2-methyl-4-nitrophenyl)pyridine, and then add wet palladium carbon to finally obtain 5-Methyl-2-(1-Methylethoxy)-4-(4-piperidinyl)- BenzenaMine hydrochloride (1:2).

5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2) Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2) Suppliers

Shandong Xuande Pharmaceutical Technology Co. LTD
Tel
18866895588
Fax
0531-82777287
Email
dingjiaying@shiningpharm.com
Country
China
ProdList
163
Advantage
55
Jiangsu Tairuite Pharmaceutical Technology Co., Ltd
Tel
15151368970
Email
sweetingyuanyuan@163.com
Country
China
ProdList
31
Advantage
58
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
5000
Advantage
55
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shanghai Xiannuo Biotechnology Co., Ltd.
Tel
021-50718719 13918719472
Fax
021-50718719
Country
China
ProdList
979
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9510
Advantage
58
ExcelChemical (Shanghai) Chemical Technology Co., Ltd.
Tel
+86 13671938079
Fax
+86-021-50829787
Country
China
ProdList
39
Advantage
55
DONGSHENG CHIRAL PHARMA
Tel
15800326364 18051538752
Email
582512789@qq.com
Country
China
ProdList
449
Advantage
55
Jinan XuanDe Chemical Co., Ltd.
Tel
0531-88803958 18866891188
Fax
0531-82777287
Email
18853169188@163.com
Country
China
ProdList
193
Advantage
58
Nanjing First Pharmaceutical Co., Ltd.
Tel
025-83172655 13585105703
Fax
+86-25-86501191
Email
sales@njfirstpharm.com
Country
China
ProdList
110
Advantage
60
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View Lastest Price from 5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2) manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
2-Isopropoxy-5-methyl-4-(piperidin-4-yl)aniline dihydrochloride 1380575-45-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-30
Hebei Yanxi Chemical Co., Ltd.
Product
5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride 1380575-45-0
Price
US $20.00/KG
Min. Order
1KG
Purity
0.99
Supply Ability
20TONS/MON
Release date
2023-09-04
Shanghai CRM New Material Technology Co., LTD
Product
5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2) 1380575-45-0
Price
US $10.00-15.00/g
Min. Order
10g
Purity
99%
Supply Ability
2546245
Release date
2022-09-20

1380575-45-0, 5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2)Related Search:


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  • 5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)- benzenamine (dihydrochloride)
  • 2-Isopropoxy-5-methyl-4-(4-piperidyl)aniline Dihydrochloride
  • 5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)-phenylamine dihydrochloride
  • 5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2)
  • 2-isopropoxy-5-Methyl-4-(piperidin-4-yl)aniline dihydrochloride
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  • Benzenamine, 5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)- (hydrochloride)(1:2)
  • CR-14
  • 5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride
  • (1-Methylethoxy)-4-(4-piperidinyl)- BenzenaMine hydrochloride (1:2)
  • 5-Methyl-2-(1-Methylethoxy)-4-
  • 5-Methyl-2-(1-Methylethoxy)-4-(4-piperidinyl)-Benzenamine hy...
  • 5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- Benzenamine dihcl
  • Intermediate Impurity 31
  • Intermediate Impurity 32
  • 1380575-45-0
  • API