ChemicalBook > CAS DataBase List > 3-benzyl-6-bromo-2-chloroquinoline
3-benzyl-6-bromo-2-chloroquinoline
- Product Name
- 3-benzyl-6-bromo-2-chloroquinoline
- CAS No.
- 654655-68-2
- Chemical Name
- 3-benzyl-6-bromo-2-chloroquinoline
- Synonyms
- Bedaquiline Impurity B;Brilanestrant Impurity 11;Bedaquiline Fumarate Impurity 5;3-benzyl-6-bromo-2-chloroquinoline;6-Bromo-3-benzyl-2-chloroquinolone;6-Bromo-2-chloro-3-(phenylmethyl)quinoline;Quinoline, 6-bromo-2-chloro-3-(phenylmethyl)-;3-benzyl-6-bromo-2-chloroquinoline（Beida quinoline intermediate ）
- CBNumber
- CB32522783
- Molecular Formula
- C16H11BrClN
- Formula Weight
- 332.62
- MOL File
- 654655-68-2.mol
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3-benzyl-6-bromo-2-chloroquinoline Property
- Melting point:
- 111-112℃
- Boiling point:
- 435.9±40.0 °C(Predicted)
- Density
- 1.482±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -0.42±0.50(Predicted)
- Appearance
- White to yellow Solid
- InChI
- InChI=1S/C16H11BrClN/c17-14-6-7-15-12(10-14)9-13(16(18)19-15)8-11-4-2-1-3-5-11/h1-7,9-10H,8H2
- InChIKey
- UGXUDVNBDYIJHJ-UHFFFAOYSA-N
- SMILES
- N1C2C(=CC(Br)=CC=2)C=C(CC2=CC=CC=C2)C=1Cl
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
AK Scientific
- Product number
- Y1234
- Product name
- 3-Benzyl-6-bromo-2-chloroquinoline
- Packaging
- 1g
- Price
- $39
- Updated
- 2021/12/16
AK Scientific
- Product number
- Y1234
- Product name
- 3-Benzyl-6-bromo-2-chloroquinoline
- Packaging
- 5g
- Price
- $94
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- HCH0364357
- Product name
- 3-BENZYL-6-BROMO-2-CHLOROQUINOLINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.79
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 094881
- Product name
- 3-Benzyl-6-bromo-2-chloroquinoline
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $742
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 094881
- Product name
- 3-Benzyl-6-bromo-2-chloroquinoline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $1647
- Updated
- 2021/12/16
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3-benzyl-6-bromo-2-chloroquinoline Chemical Properties,Usage,Production
Uses
3-Benzyl-6-bromo-2-chloroquinoline is an intermediate in the synthesis of (αS,βR)-Bedaquiline (B119540), which is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References
[1] Tetrahedron, 2007, vol. 63, # 2, p. 451 - 460
[2] Patent: WO2009/91324, 2009, A1. Location in patent: Page/Page column 20-21
3-benzyl-6-bromo-2-chloroquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-benzyl-6-bromo-2-chloroquinoline manufacturers
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- 3-benzyl-6-bromo-2-chloroquinoline 654655-68-2
- Price
- US $10.00/KG
- Min. Order
- 100KG
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-11-22
Henan Aochuang Chemical Co.,Ltd.
- Product
- 3-benzyl-6-bromo-2-chloroquinoline 654655-68-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-30
Shaanxi Dideu New Materials Co. Ltd
- Product
- 3-benzyl-6-bromo-2-chloroquinoline 654655-68-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 10000KGS
- Release date
- 2025-02-18
654655-68-2, 3-benzyl-6-bromo-2-chloroquinolineRelated Search:
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