1-Boc-4-chloro-3-formylindole

Product Name: 1-Boc-4-chloro-3-formylindole
CAS No.: 914349-00-1
Chemical Name: 1-Boc-4-chloro-3-formylindole
Synonyms: 1-Boc-4-chloro-3-formylindole;4-Chloro-3-formyl-1H-indole, N-BOC protected;4-Chloro-3-formyl-1H-indole,N-BOCprotected98%;tert-butyl 4-chloro-3-formylindole-1-carboxylate;4-Chloro-3-formyl-1H-indole, N-BOC protected 98%;tert-Butyl 4-chloro-3-forMyl-1H-indole-1-carboxylate;1H-INDOLE-1-CARBOXYLIC ACID, 4-CHLORO-3-FORMYL-, 1,1-DIMETHYLETHYL ESTER;tert-Butyl 4-chloro-3-formyl-1H-indole-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-chloro-1H-indole-3-carboxaldehyde
CBNumber: CB22471073
Molecular Formula: C14H14ClNO3
Formula Weight: 279.72
MOL File: 914349-00-1.mol

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1-Boc-4-chloro-3-formylindole Property

Boiling point:: 409.4±48.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
Appearance: White to off-white Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B807093
Product name: tert-Butyl4-Chloro-3-formyl-1H-indole-1-carboxylate
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB154007
Product name: 1-Boc-4-Chloro-3-formylindole
Packaging: 1g
Price: $110
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB154007
Product name: 1-Boc-4-Chloro-3-formylindole
Packaging: 2g
Price: $191
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB154007
Product name: 1-Boc-4-Chloro-3-formylindole
Packaging: 500mg
Price: $65
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-5-Q5
Product name: 4-Chloroindole-3-carboxaldehyde, N-Boc protected
Purity: 98%
Packaging: 1g
Price: $68
Updated: 2021/12/16

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1-Boc-4-chloro-3-formylindole Chemical Properties,Usage,Production

Synthesis

876-72-2

24424-99-5

914349-00-1

General procedure for the synthesis of 1-Boc-4-chloro-3-formylindole from 4-chloroindole-3-carboxaldehyde and di-tert-butyl dicarbonate: To a solution of 4-chloroindole-3-carboxaldehyde (1.0 eq.) and di-tert-butyl dicarbonate (1.2 eq.) in acetonitrile was added DMAP (0.1 eq.). The reaction mixture was stirred at room temperature overnight. After completion of the reaction, the reaction mixture was concentrated under reduced pressure. The residue was dissolved in dichloromethane and washed with saturated sodium bicarbonate solution. The organic and aqueous phases were separated. The aqueous phase was extracted with dichloromethane. All organic phases were combined and washed sequentially with saturated ammonium chloride solution, water and brine. The organic phase was dried with magnesium sulfate, filtered and concentrated under reduced pressure. The resulting BOC-protected 1-Boc-4-chloro-3-formylindole can be used in the next step without further purification.

References

[1] Journal of Medicinal Chemistry, 2015, vol. 58, # 23, p. 9179 - 9195
[2] Patent: WO2013/45516, 2013, A1. Location in patent: Page/Page column 129; 151

1-Boc-4-chloro-3-formylindole Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Boc-4-chloro-3-formylindole Suppliers

China 14 India 1 United Kingdom 2 United States 6 Global 23

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Shanghai Witofly Chemical Co.,Ltd

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Email: sales@witofly.com
Country: China
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Advantage: 52

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Sichuan BaiPeng Biotechnology Co., Ltd.

Tel: 028-65791793 18140026355
Fax: QQ568470422
Email: 568470422@qq.com
Country: China
ProdList: 9997
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Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
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Changzhou Kechem Bio-Scientific Co., LTD.

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Country: China
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Shanghai Haohong Pharmaceutical Co., Ltd.

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Country: China
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Changzhou Qianai Biotechnology Co., Ltd

Tel: 051915240519135 13961152745
Email: yudiguimo@126.COM
Country: China
ProdList: 10000
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LEADMEDPHARM CO.,LTD

Tel: 13674959855 13674959855
Email: sales@synthontech.com
Country: China
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Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

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View Lastest Price from 1-Boc-4-chloro-3-formylindole manufacturers

Career Henan Chemica Co

Product: 1-Boc-4-chloro-3-formylindole 914349-00-1
Price: US $0.01/KG
Min. Order: 1KG
Purity: 95%-99%
Supply Ability: 1kg; 5kg; 10kg
Release date: 2020-10-28

914349-00-1, 1-Boc-4-chloro-3-formylindoleRelated Search:

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1-Boc-4-chloro-3-formylindole

4-Chloro-3-formyl-1H-indole, N-BOC protected 98%

tert-Butyl 4-chloro-3-formyl-1H-indole-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-chloro-1H-indole-3-carboxaldehyde

tert-Butyl 4-chloro-3-forMyl-1H-indole-1-carboxylate

1H-INDOLE-1-CARBOXYLIC ACID, 4-CHLORO-3-FORMYL-, 1,1-DIMETHYLETHYL ESTER

4-Chloro-3-formyl-1H-indole,N-BOCprotected98%

tert-butyl 4-chloro-3-formylindole-1-carboxylate

4-Chloro-3-formyl-1H-indole, N-BOC protected

914349-00-1