1-Boc-3-(cyanomethylene)azetidine
Uses- Product Name
- 1-Boc-3-(cyanomethylene)azetidine
- CAS No.
- 1153949-11-1
- Chemical Name
- 1-Boc-3-(cyanomethylene)azetidine
- Synonyms
- tert-butyl 3-(cyanoMethylene)azetidine-1-carboxylate;benzyl 3-(cyanomethylene)azetidine-1-carboxylate;3-Cyanomethylene-azetidine-1-carboxylic acid tert-butyl ester;Baricitinib-013;Baricitinib Impurity 10;tert-Butyl 3-(cyanomethylene);1-Boc-3-(cyanomethylene)azetidine;P-Hydroxy phenyl butanone (Raspberry ketone);1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine;ert-butyl3-(cyanomethylidene)azetidine-1-carboxylate
- CBNumber
- CB22485423
- Molecular Formula
- C10H14N2O2
- Formula Weight
- 194.23
- MOL File
- 1153949-11-1.mol
1-Boc-3-(cyanomethylene)azetidine Property
- Boiling point:
- 309.7±35.0 °C(Predicted)
- Density
- 1.215
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- powder to crystal
- pka
- -1.88±0.20(Predicted)
- color
- White to Orange to Green
Safety
- RIDADR
- UN 3439 6.1/PG III
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- B5217
- Product name
- 1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine
- Purity
- >95.0%(GC)
- Packaging
- 200mg
- Price
- $52
- Updated
- 2024/03/01
- Product number
- B5217
- Product name
- 1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine
- Purity
- >95.0%(GC)
- Packaging
- 1g
- Price
- $148
- Updated
- 2024/03/01
- Product number
- B117850
- Product name
- 1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B117850
- Product name
- 1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine
- Packaging
- 25g
- Price
- $340
- Updated
- 2021/12/16
- Product number
- OR930876
- Product name
- tert-Butyl3-(cyanomethylene)azetidine-1-carboxylate
- Purity
- 95%
- Packaging
- 10g
- Price
- $135
- Updated
- 2021/12/16
1-Boc-3-(cyanomethylene)azetidine Chemical Properties,Usage,Production
Uses
1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine is used in the synthesis of baricitinib via Horner-Emmons reaction of tert-butyl-oxoazetidine-carboxylate followed by sulfonamidation, nucleophilic addition. and subsequent Suzuki-coupling reaction.
Uses
1-(tert-Butoxycarbonyl)-3-(cyanomethylene)azetidine is used in the synthesis of baricitinib via Horner-Emmons reaction of tert-butyl-oxoazetidine-carboxylate followed by sulfonamidation, nucleophilic addition. and subsequent Suzuki-coupling reaction.
1-Boc-3-(cyanomethylene)azetidine Preparation Products And Raw materials
Raw materials
Preparation Products
1-Boc-3-(cyanomethylene)azetidine Suppliers
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View Lastest Price from 1-Boc-3-(cyanomethylene)azetidine manufacturers
- Product
- 1-Boc-3-(cyanomethylene)azetidine 1153949-11-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-29
- Product
- tert-butyl 3-(cyanomethylidene)azetidine-1-carboxylate 1153949-11-1
- Price
- US $880.00/g
- Min. Order
- 1g
- Purity
- 98
- Supply Ability
- 500 Kg
- Release date
- 2024-04-05
- Product
- 1-Boc-3-(cyanomethylene)azetidine 1153949-11-1
- Price
- US $500.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 2000 ton/year
- Release date
- 2023-12-21