1-Boc-Azetidine-3-yl-methanol

Product Name: 1-Boc-Azetidine-3-yl-methanol
CAS No.: 142253-56-3
Chemical Name: 1-Boc-Azetidine-3-yl-methanol
Synonyms: TERT-BUTYL 3-(HYDROXYMETHYL)AZETIDINE-1-CARBOXYLATE;EOS-61767;Boc-Azetidin-3-ylMethanol;1-Boc-3-(hydroxymethyl)az...;1-BOC-AZETIDINE-3-YL METHANOL;1-Boc-3-azetidinemethanol,95%;1-Boc-3-azetidineMethanol, 95%;1-N-Boc-3-hydroxyMethyazetidine;1-Boc-3-(hydroxymethyl)azetidine;1-Boc-3-(hydroxyMethyl)azetidine, 97+%
CBNumber: CB8246260
Molecular Formula: C9H17NO3
Formula Weight: 187.24
MOL File: 142253-56-3.mol

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1-Boc-Azetidine-3-yl-methanol Property

Melting point:: 55 °C
Boiling point:: 268-273℃
Density: 1.115
Flash point:: 117°(243°F)
storage temp.: 2-8°C
solubility: Soluble in Dimethyl sulfoxide (DMSO).
pka: 14.82±0.10(Predicted)
form: powder to lump
color: White to Almost white
InChI: InChI=1S/C9H17NO3/c1-9(2,3)13-8(12)10-4-7(5-10)6-11/h7,11H,4-6H2,1-3H3
InChIKey: HXRDRJKAEYHOBB-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CC(CO)C1

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 23-26-37-60
TSCA: No
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B3992
Product name: 1-(tert-Butoxycarbonyl)-3-azetidinemethanol
Purity: >98.0%(GC)
Packaging: 1g
Price: $121
Updated: 2024/03/01

Alfa Aesar

Product number: H57112
Product name: 1-Boc-3-azetidinemethanol, 95%
Packaging: 500mg
Price: $127
Updated: 2023/06/20

Alfa Aesar

Product number: H57112
Product name: 1-Boc-3-azetidinemethanol, 95%
Packaging: 250mg
Price: $68.2
Updated: 2021/12/16

TRC

Product number: B750283
Product name: tert-butyl3-(acetoxymethyl)azetidine-1-carboxylate
Packaging: 2.5g
Price: $130
Updated: 2021/12/16

Usbiological

Product number: 261930
Product name: 1-Boc-azetidine-3-yl-methanol
Packaging: 50g
Price: $1018
Updated: 2021/12/16

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1-Boc-Azetidine-3-yl-methanol Chemical Properties,Usage,Production

Description

1-Boc-Azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). This compound is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Chemical Properties

Clear colorless liquid

Uses

It is an intermediate in organic syntheses

1-Boc-Azetidine-3-yl-methanol Preparation Products And Raw materials

Raw materials

Acetonitrile Toluene Di-tert-butyl dicarbonate Benzylamine Formaldehyde N,N-Diisopropylethylamine Sodium borohydride Palladium Boron trifluoride diethyl etherate Tetrahydrofuran Trifluoroacetic anhydride Lithium Aluminum Hydride Hydrochloric acid Dichloromethane Methanol Sodium hydroxide Diethyl malonate Thionyl chloride Ammonia

Preparation Products

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1-Boc-Azetidine-3-yl-methanol Suppliers

Americas 1 Belgium 2 Canada 2 China 203 Europe 1 France 1 Germany 2 India 5 Japan 2 South Korea 1 The Netherlands 1 United Kingdom 7 United States 34 Global 262

PharmaBlock Sciences (Nanjing),Inc.

Tel: 400-0255188 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 4986
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Ark Pharm, Inc.

Tel: 847-367-3680
Fax: 847-367-3681
Email: sales@arkpharminc.com
Country: United States
ProdList: 1670
Advantage: 56

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
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JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9984
Advantage: 60

Changzhou Huanling Chemical Co., Ltd.

Tel: 0519-89803565 13776850645
Fax: 0519-89803575
Email: info4@huanlingchem.com
Country: China
ProdList: 639
Advantage: 68

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9551
Advantage: 66

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View Lastest Price from 1-Boc-Azetidine-3-yl-methanol manufacturers

Anhui Ruihan Technology Co., Ltd

Product: 1-Boc-azetidine-3-yl-methanol 142253-56-3
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000t/year
Release date: 2023-09-08

Career Henan Chemical Co

Product: 1-Boc-azetidine-3-ylmethanol 142253-56-3
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: as request
Release date: 2018-12-23

142253-56-3, 1-Boc-Azetidine-3-yl-methanolRelated Search:

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1-Boc-3-azetidineMethanol, 95%

Boc-Azetidin-3-ylMethanol

1-(tert-Butoxycarbonyl)-3-azetidineMethanol

1-Azetidinecarboxylic acid, 3-(hydroxyMethyl)-, 1,1-diMethylethyl ester

EOS-61767

1-Boc-3-(hydroxyMethyl)azetidine, 97+%

TERT-BUTYL 3-(HYDROXYMETHYL)AZETIDINE-1-CARBOXYLATE

3-HYDROXYMETHYL-AZETIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

1-BOC-AZETIDINE-3-YL METHANOL

3-(Hydroxymethyl)azetidine-1-carboxylate

1-Boc-3-(hydroxymethyl)azetidine

1-Boc-3-(hydroxymethyl)az...

1-N-Boc-3-hydroxyMethyazetidine

tert-butyl 2-(azetidin-3-yl)-2-hydroxyacetate

1-(tert-Butoxycarbonyl)-3-azetidinemethanol &gt

1-Boc-3-azetidinemethanol,95%

1-tert-Butoxycarbonyl-3-hydroxymethylazetidine

142253-56-3