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1-Boc-Azetidine-3-yl-methanol

Product Name
1-Boc-Azetidine-3-yl-methanol
CAS No.
142253-56-3
Chemical Name
1-Boc-Azetidine-3-yl-methanol
Synonyms
TERT-BUTYL 3-(HYDROXYMETHYL)AZETIDINE-1-CARBOXYLATE;EOS-61767;Boc-Azetidin-3-ylMethanol;1-Boc-3-(hydroxymethyl)az...;1-BOC-AZETIDINE-3-YL METHANOL;1-Boc-3-azetidinemethanol,95%;1-Boc-3-azetidineMethanol, 95%;1-N-Boc-3-hydroxyMethyazetidine;1-Boc-3-(hydroxymethyl)azetidine;1-Boc-3-(hydroxyMethyl)azetidine, 97+%
CBNumber
CB8246260
Molecular Formula
C9H17NO3
Formula Weight
187.24
MOL File
142253-56-3.mol
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1-Boc-Azetidine-3-yl-methanol Property

Melting point:
55 °C
Boiling point:
268-273℃
Density 
1.115
Flash point:
117°(243°F)
storage temp. 
2-8°C
solubility 
Soluble in Dimethyl sulfoxide (DMSO).
pka
14.82±0.10(Predicted)
form 
powder to lump
color 
White to Almost white
InChI
InChI=1S/C9H17NO3/c1-9(2,3)13-8(12)10-4-7(5-10)6-11/h7,11H,4-6H2,1-3H3
InChIKey
HXRDRJKAEYHOBB-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CC(CO)C1
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
23-26-37-60
TSCA 
No
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B3992
Product name
1-(tert-Butoxycarbonyl)-3-azetidinemethanol
Purity
>98.0%(GC)
Packaging
1g
Price
$121
Updated
2024/03/01
Alfa Aesar
Product number
H57112
Product name
1-Boc-3-azetidinemethanol, 95%
Packaging
500mg
Price
$127
Updated
2023/06/20
Alfa Aesar
Product number
H57112
Product name
1-Boc-3-azetidinemethanol, 95%
Packaging
250mg
Price
$68.2
Updated
2021/12/16
TRC
Product number
B750283
Product name
tert-butyl3-(acetoxymethyl)azetidine-1-carboxylate
Packaging
2.5g
Price
$130
Updated
2021/12/16
Usbiological
Product number
261930
Product name
1-Boc-azetidine-3-yl-methanol
Packaging
50g
Price
$1018
Updated
2021/12/16
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1-Boc-Azetidine-3-yl-methanol Chemical Properties,Usage,Production

Description

1-Boc-Azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). This compound is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Chemical Properties

Clear colorless liquid

Uses

It is an intermediate in organic syntheses

1-Boc-Azetidine-3-yl-methanol Preparation Products And Raw materials

Raw materials

Acetonitrile Toluene Di-tert-butyl dicarbonate Benzylamine Formaldehyde N,N-Diisopropylethylamine Sodium borohydride Palladium Boron trifluoride diethyl etherate Tetrahydrofuran Trifluoroacetic anhydride Lithium Aluminum Hydride Hydrochloric acid Dichloromethane Methanol Sodium hydroxide Diethyl malonate Thionyl chloride Ammonia

Preparation Products

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1-Boc-Azetidine-3-yl-methanol Suppliers

Americas 1 Belgium 2 Canada 2 China 216 Europe 1 France 1 Germany 2 India 5 Japan 2 South Korea 1 The Netherlands 1 United Kingdom 7 United States 34 Global 275
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
Santo Righello Pvt. Ltd
Tel
--
Fax
--
Email
marketing@santorighello.com
Country
India
ProdList
918
Advantage
58
Reax Chemicals
Tel
--
Fax
--
Country
India
ProdList
4217
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 1-Boc-Azetidine-3-yl-methanol manufacturers

Anhui Ruihan Technology Co., Ltd
Product
1-Boc-azetidine-3-yl-methanol 142253-56-3
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000t/year
Release date
2023-09-08
Career Henan Chemical Co
Product
1-Boc-azetidine-3-ylmethanol 142253-56-3
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-23

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