Mitoquinone mesylate
- Product Name
- Mitoquinone mesylate
- CAS No.
- 845959-50-4
- Chemical Name
- Mitoquinone mesylate
- Synonyms
- MitoQ;MitoQ mesylate;MitoQ10 mesylate;Mitoquinol Mesylate;Mitoquinone mesylate;Mitoquinone mesylate (MitoQ);MitoQ (Mitoquinone) mesylate;Mitoxantrone Methanesulfonate;Mitoquinone (MitoQ10) mesylate;MitoQ mesylate|||MitoQ10 mesylate
- CBNumber
- CB22505185
- Molecular Formula
- C38H47O7PS
- Formula Weight
- 678.814341
- MOL File
- 845959-50-4.mol
Mitoquinone mesylate Property
- storage temp.
- -20°C
- solubility
- Soluble in DMSO.
- form
- waxy solid
- color
- Orange
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
- InChIKey
- GVZFUVXPTPGOQT-UHFFFAOYSA-M
- SMILES
- [P+](CCCCCCCCCCC1C(=O)C(OC)=C(OC)C(=O)C=1C)(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1.CS([O-])(=O)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 29317
- Product name
- Mitoquinone (mesylate)
- Packaging
- 1mg
- Price
- $29
- Updated
- 2024/03/01
- Product number
- 29317
- Product name
- Mitoquinone (mesylate)
- Packaging
- 25mg
- Price
- $246
- Updated
- 2024/03/01
- Product number
- 29317
- Product name
- Mitoquinone (mesylate)
- Packaging
- 5mg
- Price
- $78
- Updated
- 2024/03/01
- Product number
- 29317
- Product name
- Mitoquinone (mesylate)
- Packaging
- 10mg
- Price
- $141
- Updated
- 2024/03/01
- Product number
- M372215
- Product name
- MitoquinoneMesylate
- Packaging
- 10mg
- Price
- $180
- Updated
- 2021/12/16
Mitoquinone mesylate Chemical Properties,Usage,Production
Description
Mitoquinone mesylate (845959-50-4) is a mitochondria-targeted antioxidant.? Displays cardio- and neuroprotective effects.1 Displays beneficial effects in mouse models of Alzheimer’s disease.2,3 Protects pancreatic β-cells against oxidative stress and improves insulin secretion.4 Inhibits respiratory syncytial virus (RSV) production via lowering of mitochondrial ROS levels.5 Cell permeable.
Uses
Mitoquinone Mesylate is used in the transport and metabolism of some cationic ubiquinone antioxidants.
in vivo
Mitoquinone (MitoQ) treatment significantly reduces pancreatic oedema and neutrophil infiltration. MitoQ dose-dependently increases serum amylase with an approximate doubling at the higher dose. MitoQ treatment nearly doubles lung MPO activity induced by Caerulein with a significant increase of serum IL-6 levels also evident at 10 mg/kg (dose 1)[2].
References
1.Ghosh et al. (2010), Neuroprotection by a mitochondria-targeted drug in a Parkinson’s disease model; Free Radic. Biol. Med., 49 1674
2.McManus et al. (2011), The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer’s disease; J. Neurosci., 31 15703
3.Young and Franklin, (2019), The mitochondria-targeted antioxidant MitoQ inhibits memory loss, neuropathology, and extends lifespan in aged 3xTg-AD mice; Cell Neurosci. 101 103409
4.Lim et al. (2011), Mitochondria-targeted antioxidants protect pancreatic b-cells against oxidative stress and improve insulin secretion in glucotoxicity and glucolipotoxicity; Cell Physiol. Biochem., 28 873
5.MengJie et al. (2019), Subversion of Host Cell Mitochondria by RSV to Favor Virus Production in Dependent on Inhibition of Mitochondrial Complex I and ROS Generation; Cells 8 1417
Mitoquinone mesylate Preparation Products And Raw materials
Raw materials
Preparation Products
Mitoquinone mesylate Suppliers
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View Lastest Price from Mitoquinone mesylate manufacturers
- Product
- Mitoquinone mesylate 845959-50-4
- Price
- US $2.00-6.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-ton
- Release date
- 2025-07-28
- Product
- Mitoquinone mesylate 845959-50-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5,000KG
- Release date
- 2024-07-25
- Product
- Mitoquinone mesylate 845959-50-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- Min98% HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2020-01-01