4-Chlorobutanal dimethyl acetal
- Product Name
- 4-Chlorobutanal dimethyl acetal
- CAS No.
- 29882-07-3
- Chemical Name
- 4-Chlorobutanal dimethyl acetal
- Synonyms
- 4-CHLOROBUTYRALDEHYDE DIMETHYL ACETAL;SUMATRIPTAN Impurity;4-chloro-1,1-dimethoxybutane;1-dimethoxybutane;4,4-Dimethoxybutyl C;4,4-Dimethoxybutyl Chloride;SuMatriptan Chloro IMpurity;1-Chloro-4,4-dimethoxybutane;Butane,4-chloro-1,1-dimethoxy-;4-CHLOROBUTANAL DIMETHYL ACETAL
- CBNumber
- CB2251231
- Molecular Formula
- C6H13ClO2
- Formula Weight
- 152.62
- MOL File
- 29882-07-3.mol
4-Chlorobutanal dimethyl acetal Property
- Boiling point:
- 120 °C / 40mmHg
- Density
- 1.04
- refractive index
- 1.4270-1.4310
- Flash point:
- 43°C(lit.)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Chloroform, Methanol
- form
- Oil
- color
- Clear Colourless
- Stability:
- Moisture Sensitive
- InChIKey
- LTLKJYMNUSSFAH-UHFFFAOYSA-N
- CAS DataBase Reference
- 29882-07-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C2179
- Product name
- 4-Chlorobutyraldehyde Dimethyl Acetal
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $50
- Updated
- 2025/07/31
- Product number
- C2179
- Product name
- 4-Chlorobutyraldehyde Dimethyl Acetal
- Purity
- >97.0%(GC)
- Packaging
- 25g
- Price
- $148
- Updated
- 2025/07/31
- Product number
- C365036
- Product name
- 4-ChlorobutanalDimethylAcetal90%
- Packaging
- 25g
- Price
- $295
- Updated
- 2021/12/16
- Product number
- C365036
- Product name
- 4-ChlorobutanalDimethylAcetal90%
- Packaging
- 100g
- Price
- $990
- Updated
- 2021/12/16
- Product number
- 8259
- Product name
- 4-ChlorobutanalDimethylAcetal90%
- Packaging
- 5G
- Price
- $1880
- Updated
- 2021/12/16
4-Chlorobutanal dimethyl acetal Chemical Properties,Usage,Production
Chemical Properties
Colorless Liquid
Uses
4-Chlorobutanal Dimethyl Acetal 90% is a compound useful in organic synthesis and other chemical processes. It is used as an intermediate in the synthesis of aripiprazole, buspirone, and NAN-190 via reductive alkylation of piperazine derivatives with aldehydes
Synthesis
67-56-1
763101-16-2
29882-07-3
Preparation of 4-chlorobutanal dimethanol: 72 g (0.49 mol) of 4-chloro-1-acetoxy-1-butene was dissolved in 300 mL of anhydrous methanol, to which were added 240 g (7.5 mol) of methanol and 15 g of acidic ion exchange resin catalyst treated with macroporous resin 15. The mixture was stirred overnight under reflux conditions and the complete conversion of the E and Z isomers of 4-chloro-1-acetoxy-1-butene to a single high-boiling product, accompanied by a small number of side reactions, was confirmed by GC analysis. Upon completion of the reaction, the mixture was filtered to recover the catalyst and the filtrate was treated with 5 g of solid sodium bicarbonate. Excess methanol was removed by distillation under reduced pressure until the volume was reduced to about 50 mL. The liquid was decanted from the insoluble sodium bicarbonate and distilled through a 6-inch Vigro fractionating column at 25 mm Hg. A colorless fraction with a boiling range of 83-85 °C was collected to give 55.0 g of product (74.4% of the theoretical yield).NMR analysis confirmed the fraction as pure 4-chlorobutanal dimethyl acetal.
References
[1] Organic Preparations and Procedures International, 2004, vol. 36, # 5, p. 487 - 490
[2] Patent: US2004/192958, 2004, A1. Location in patent: Page 3
4-Chlorobutanal dimethyl acetal Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Chlorobutanal dimethyl acetal manufacturers
- Product
- 4-Chlorobutanal dimethyl acetal 29882-07-3
- Price
- US $50.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-22
- Product
- 4-Chlorobutanal dimethyl acetal 29882-07-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-26
- Product
- 4-Chlorobutanal dimethyl acetal 29882-07-3
- Price
- US $100.00/KG
- Min. Order
- 100G
- Purity
- 98%
- Supply Ability
- 100g, 1KG,10KG
- Release date
- 2018-07-25