ChemicalBook > CAS DataBase List > [2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone

[2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone

Product Name
[2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone
CAS No.
913186-74-0
Chemical Name
[2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone
Synonyms
LY 2087101;(2-Amino-5-keto)thiazole);[2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone;Methanone, [2-[(4-fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienyl-;[2-(4-Fluoro-phenylamino)-4-methyl-thiazol-5-yl]-thiophen-3-yl-methanone
CBNumber
CB22518972
Molecular Formula
C15H11FN2OS2
Formula Weight
318.39
MOL File
913186-74-0.mol
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[2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone Property

Melting point:
160 - 163°C
Boiling point:
449.1±55.0 °C(Predicted)
Density 
1.407±0.06 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
DMSO: soluble20mg/mL, clear
pka
2.71±0.10(Predicted)
form 
powder
color 
white to beige
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
36/37/39
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0870
Product name
LY 2087101
Purity
≥98% (HPLC)
Packaging
5mg
Price
$118
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0870
Product name
LY 2087101
Purity
≥98% (HPLC)
Packaging
25mg
Price
$371
Updated
2024/03/01
Tocris
Product number
4141
Product name
LY 2087101
Purity
≥98%(HPLC)
Packaging
10
Price
$193
Updated
2021/12/16
Tocris
Product number
4141
Product name
LY 2087101
Purity
≥98%(HPLC)
Packaging
50
Price
$688
Updated
2021/12/16
TRC
Product number
L485050
Product name
LY 2087101
Packaging
5mg
Price
$265
Updated
2021/12/16
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[2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone Chemical Properties,Usage,Production

Uses

LY 2087101 is a positive allosteric Nicotinic acetylcholine receptor (nAChR) modulators. nAChRs are found in the CNS and they respond to neurotransmitter acetylcholine.

Biological Activity

LY 2087101 is a selective positive allosteric potentiator of α7 and α4β2 nicotinic acetylcholine receptors (nAChRs). LY 2087101 was shown to not enhance the activity of α3β4 subtype nAChRs.

storage

Store at +4°C

[2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone Preparation Products And Raw materials

Raw materials

Preparation Products

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[2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
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913186-74-0, [2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanoneRelated Search:


  • [2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone
  • LY 2087101
  • (2-Amino-5-keto)thiazole)
  • [2-(4-Fluoro-phenylamino)-4-methyl-thiazol-5-yl]-thiophen-3-yl-methanone
  • Methanone, [2-[(4-fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienyl-
  • 913186-74-0