Vilanterol
- Product Name
- Vilanterol
- CAS No.
- 503068-34-6
- Chemical Name
- Vilanterol
- Synonyms
- CS-1833;GW642444;GW-642444;GW 642444;Vianterol;Vilantero;GW 642444X;Vilanterol;Vilanterol API;Vilanterol base
- CBNumber
- CB22542797
- Molecular Formula
- C24H33Cl2NO5
- Formula Weight
- 486.43
- MOL File
- 503068-34-6.mol
Vilanterol Property
- Boiling point:
- 646.7±55.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- solution in ethanol
- pka
- 9.99±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H370Causes damage to organs
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P307+P311IF exposed: call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 20702
- Product name
- Vilanterol
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 20702
- Product name
- Vilanterol
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $68
- Updated
- 2024/03/01
- Product number
- 20702
- Product name
- Vilanterol
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $266
- Updated
- 2024/03/01
- Product number
- 5959CR
- Product name
- Vilanterol
- Packaging
- 5mg
- Price
- $394
- Updated
- 2021/12/16
- Product number
- B1005
- Product name
- Vilanterol
- Packaging
- 10mg
- Price
- $527
- Updated
- 2021/12/16
Vilanterol Chemical Properties,Usage,Production
Definition
ChEBI: An dichlorobenzene derivative that is used in the form of its trifenate salt for treatment of chronic obstructive pulmonary disease.
Biological Activity
vilanterol is a novel and selective agonist of β2-ar with a pec50 value of 10.37±0.05 [1].vilanterol is a novel long-acting β2-ar agonist (laba) with 24h activity in development for inhaled once daily treatment. in the radioligand binding studies, vilanterol has shown the binding affinity in the one-affinity site model with pkd values of 9.44±0.07 and 10.82±0.12 in the presence gpp(nh)p and absence gpp(nh)p, respectively. in dissociation studies, vilanterol has been reported to bind from the β2-ar with a dissociation t1/2 value of 3.5 min in the presence of gpp(nh)p. vilanterol has been found to have a good selectivity for β2-ar over the other β-ar receptor subtypes(β1and β3) with pec50 values of 10.37±0.05, 6.98±0.03 and 7.36±0.03, respectively. vilanterol has exhibited at least 1000-fold selectivity over both β1-and β3-ar subtypes [1].
References
[1] slack rj1, barrett vj, morrison vs, sturton rg, emmons aj, ford aj, knowles rg.in vitro pharmacological characterization of vilanterol, a novel long-acting β2-adrenoceptor agonist with 24-hour duration of action.j pharmacol exp ther. 2013 jan; 344(1):218-30.
Vilanterol Preparation Products And Raw materials
Raw materials
Preparation Products
Vilanterol Suppliers
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View Lastest Price from Vilanterol manufacturers
- Product
- Vilanterol 503068-34-6
- Price
- US $10.00-100.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100 tons
- Release date
- 2024-03-11
- Product
- Vilanterol 503068-34-6
- Price
- US $40.00-40.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-09-07
- Product
- Vilanterol 503068-34-6
- Price
- US $10.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 500tons
- Release date
- 2023-10-18