ChemicalBook > CAS DataBase List > OSI-420

OSI-420

Product Name
OSI-420
CAS No.
183320-51-6
Chemical Name
OSI-420
Synonyms
CP-473420;OSI420 HCl;7-(2’OSI-420 USP/EP/BP;DesMethyl Erlotinib;OSI-420 hydrochloride;6-O-Desmethyl Erlotinib 2;OSI-420 (DesMethyl Erlotinib);Desmethyl Erlotinib (OSI-420);Desmethyl Erlotinib hydrochloride
CBNumber
CB22561488
Molecular Formula
C21H22ClN3O4
Formula Weight
415.87
MOL File
183320-51-6.mol
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OSI-420 Property

storage temp. 
Store at -20°C
solubility 
DMSO : 50 mg/mL (120.23 mM; Need ultrasonic)
form 
Powder
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
O701030
Product name
OSI420
Packaging
10mg
Price
$435
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
KIN0001381
Product name
DESMETHYL ERLOTINIB
Purity
95.00%
Packaging
5MG
Price
$499.47
Updated
2021/12/16
ChemScene
Product number
CS-0467
Product name
DesmethylErlotinib(hydrochloride)
Purity
98.69%
Packaging
50mg
Price
$642
Updated
2021/12/16
ChemScene
Product number
CS-0467
Product name
DesmethylErlotinib(hydrochloride)
Purity
98.69%
Packaging
5mg
Price
$144
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
KIN0001381
Product name
DESMETHYL ERLOTINIB
Purity
95.00%
Packaging
2MG
Price
$234
Updated
2021/12/16
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OSI-420 Chemical Properties,Usage,Production

Uses

OSI 420 can be used in biological study of effects of cytochrome P 450 3A on pharmacokinetic interaction between erlotinib and docetaxel in rats.

Uses

OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.

target

EGFR

OSI-420 Preparation Products And Raw materials

Raw materials

Preparation Products

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OSI-420 Suppliers

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View Lastest Price from OSI-420 manufacturers

Career Henan Chemical Co
Product
OSI-420 183320-51-6
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1ton
Release date
2020-01-10

183320-51-6, OSI-420Related Search:


  • Ethanol, 2-[[4-[(3-ethynylphenyl)aMino]-7-(2-Methoxyethoxy)-6-quinazolinyl]oxy]-, hydrochloride
  • OSI-420 (DesMethyl Erlotinib,CP-473420)
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  • OSI-420 hydrochloride
  • OSI-420 (DesMethyl Erlotinib)
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  • 6-O-Desmethyl Erlotinib 2
  • OSI420/OSI-420/Desmethyl erlotinib /O-Desmethylerlotinib hydrochloride
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  • OSI420 HCl
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  • 2-[4-(3-ethynylanilino)-7-(2-methoxyethoxy)quinazolin-6-yl]oxyethanol
  • 6-O-Desmethyl Erlotinib Hydrochloride
  • DESMETHYL ERLOTINIB; CP-473420; OSI420; OSI 420; CP473420; CP 473420
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  • 183320-51-6
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  • Inhibitors