ChemicalBook > CAS DataBase List > (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate

(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate

Product Name: (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate
CAS No.: 250159-48-9
Chemical Name: (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate
Synonyms: Platinum hydrate;Miriplatin hydrate;Miriplatin monohydrate;(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate;SM-11355 (hydrate)|||Miripla|||Miriplatin|||SM 11355|||SM11355|||SM-11355|||Miriplatin hydrate
CBNumber: CB22565875
Molecular Formula: C34H68N2O5Pt
Formula Weight: 780.01
MOL File: 250159-48-9.mol

Less

(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate Property

storage temp.: Store at -20°C
solubility: 25℃: DMSO
form: Powder

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0019571
Product name: MIRIPLATIN HYDRATE
Purity: 95.00%
Packaging: 5MG
Price: $496.98
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 17572
Product name: Miriplatinhydrate
Purity: 98%
Packaging: 5mg
Price: $990
Updated: 2021/12/16

Less

(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate Chemical Properties,Usage,Production

Uses

Miriplatin hydrate (SM-11355 hydrate) is a chemotherapy agent which belongs to the class of alkylating agents.

Biological Activity

Miriplatin hydrate (SM-11355 hydrate) is an effective chemotherapeutic agent and is a kind of alkylator.

in vitro

Miriplatin suspended in lipiodol (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis.

in vivo

Miriplatin (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells.

References

[1] Kishimoto S, et al. Antitumor effects of a novel lipophilic platinum complex (SM-11355) against a slowly-growing rat hepatic tumor after intra-hepatic arterial administration. Biol Pharm Bull. 2000 Mar;23(3):344-8. DOI:10.1248/bpb.23.344
[2] Hanada M, et al. Intra-hepatic arterial administration with miriplatin suspended in an oily lymphographic agent inhibits the growth of tumors implanted in rat livers by inducing platinum-DNA adducts to form and massive apoptosis. Cancer Chemother Pharmacol. 2009 Aug;64(3):473-83. DOI:10.1007/s00280-008-0895-3

(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Less

(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate Suppliers

China 46 United States 5 Global 51

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

China Nobel Chem Co., Limited

Tel: +86(0)21 60484900
Fax: +86(0)21 60484900
Country: China
ProdList: 764
Advantage: 50

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

Wuhan Dahua Weiye Pharmaceutical Chemical Co., Ltd.

Tel: 027-59420981,18702770802
Fax: 027-83322098
Country: China
ProdList: 1975
Advantage: 50

Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
Fax: 021-61350662
Email: sales@zehanbiopharma.com
Country: China
ProdList: 984
Advantage: 55

Pharmacodia (Beijing) Co.,Ltd

Tel: +86-400-851-9921
Fax: +86-10-82826195
Email: sales@pharmacodia.com
Country: China
ProdList: 2317
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9125
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Zhongshan Geometric Biological Technology Co., Ltd.

Tel
Email: 2953972351@qq.com
Country: China
ProdList: 253
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Shanghai Botuo Biotechnology Co., LTD

Tel: 16621358918
Fax: QQ:402135374
Email: botuopharma888@163.com
Country: China
ProdList: 9208
Advantage: 58

NANJING WEDO PHARMATECH CO.,LTD.

Tel: 15189836218
Email: wedo-chem@huawe.com
Country: China
ProdList: 275
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Hubei Wanye Zhongcheng Chemical Reagent Co., Ltd.

Tel: 18671296875
Email: 1205035102@qq.com
Country: China
ProdList: 4302
Advantage: 58

Aobolihui

Tel: 0917-18691729 18691729963
Email: 2553382659@qq.com
Country: China
ProdList: 4739
Advantage: 58

Nanjing Yongyi Pharma Tech Co. , Ltd.

Tel: 13770533061
Email: renqing401@163.com
Country: China
ProdList: 323
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9835
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Adooq Bioscience LLC

Tel: 400-025-6535
Email: sales@adooq.cn
Country: China
ProdList: 6215
Advantage: 58

Ningbo Chaoming Biotechnology Co., Ltd

Tel: 13301662590
Email: mandy@atkchemical.com
Country: China
ProdList: 9343
Advantage: 58

ATK CHEMICAL COMPANY LIMITED

Tel: +undefined-21-51877795
Fax: +86 21 5161 9052/ 5187 7796
Email: ivan@atkchemical.com
Country: China
ProdList: 33024
Advantage: 60

Shanghai Likang New Materials Co., Limited

Tel: +86-16631818819 +86-17736933208
Email: 3684455296@qq.com
Country: China
ProdList: 9300
Advantage: 58

GIHI CHEMICALS CO.,LIMITED

Tel: +8618058761490
Email: info@gihichemicals.com
Country: China
ProdList: 49941
Advantage: 58

PT CHEM GROUP LIMITED

Tel: +86-85511178;
Email: peter68@ptchemgroup.com
Country: China
ProdList: 35425
Advantage: 58

Jinan Dingguo Biotechnology Co., Ltd.

Tel: 053181181593
Country: CHINA
ProdList: 155
Advantage: 58

Guangzhou Huiheng Biotechnology Co., Ltd.

Tel: 18675945663
Country: CHINA
ProdList: 126
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Proteintech China

Tel: --
Fax: --
Email: Proteintech-CN@ptglab.com
Country: CHINA
ProdList: 6290
Advantage: 58

Shanghai Hao Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: shxiyuanbio@163.com
Country: CHINA
ProdList: 6906
Advantage: 58

Xiamen Research Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1562893815@qq.com
Country: CHINA
ProdList: 6936
Advantage: 58

Shanghai Benrui Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: john.st@163.com
Country: CHINA
ProdList: 2160
Advantage: 58

Shanghai Yijie Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: SHYIJIEBIO@126.COM
Country: CHINA
ProdList: 3510
Advantage: 58

Shanghai Chaoyan Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 471161314@qq.com
Country: CHINA
ProdList: 6210
Advantage: 58

Beijing Shengke Boyuan Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 978560024@qq.com
Country: CHINA
ProdList: 6458
Advantage: 58

Beijing Baiao Innovation Technology Co., Ltd.

Tel: --
Fax: --
Email: 3007606172@qq.com
Country: CHINA
ProdList: 6002
Advantage: 58

Shanghai Han-Xiang Chemical Co., Ltd.

Tel: --
Fax: --
Email: kexianxun@gmail.com
Country: China
ProdList: 1037
Advantage: 50

Shanghai Hao Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: market@xlswkj.com
Country: CHINA
ProdList: 6793
Advantage: 58

Shanghai Weiwei Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: sales@wheybio.com
Country: CHINA
ProdList: 4398
Advantage: 58

Shandong Boyuan Pharmaceutical Co., Ltd.

Tel: --
Fax: --
Email: sales@boyuanpharm.com
Country: China
ProdList: 191
Advantage: 0

EOS Med Chemical

Tel: --
Fax: --
Email: info@eosmedchem.com
Country: China
ProdList: 26
Advantage: 50

Debye Scientific Corporation

Tel: --
Fax: --
Country: China
ProdList: 6891
Advantage: 50

250159-48-9, (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrateRelated Search:

Cisplatin Carboplatin cis-Diamminediiodoplatinum Nedaplatin LOBAPLATIN DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Picoplatin Eptaplatin Satraplatin DIBROMO(1,5-CYCLOOCTADIENE)PLATINUM(II)

(SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kN,kN']bis(tetradecanoato-kO)platinum monohydrate

Miriplatin hydrate

Miriplatin monohydrate

Platinum hydrate

SM-11355 (hydrate)|||Miripla|||Miriplatin|||SM 11355|||SM11355|||SM-11355|||Miriplatin hydrate

250159-48-9

C34H68N2O4PtH2O

Anticancer