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Eptaplatin

Product Name
Eptaplatin
CAS No.
146665-77-2
Chemical Name
Eptaplatin
Synonyms
SUNPLA;SKI 2053R;EPTAPLATIN;heptaplatin;(SP-4-2)-[(4R,5R;EPOXYPROGESTERONE;Eptaplatin, >=98%;EPTAPLATIN, SUNPLA;Eptaplatin(SKI-2053R);Eptaplatin(Heptaplatin)
CBNumber
CB2717771
Molecular Formula
C11H20N2O6Pt
Formula Weight
471.36
MOL File
146665-77-2.mol
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Eptaplatin Property

Melting point:
43-49°C
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
E591500
Product name
Eptaplatin
Packaging
50mg
Price
$910
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002576
Product name
EPTAPLATIN
Purity
95.00%
Packaging
0.025G
Price
$1044
Updated
2021/12/16
Biosynth Carbosynth
Product number
FE22772
Product name
Eptaplatin
Packaging
10 mg
Price
$95
Updated
2021/12/16
AK Scientific
Product number
N771
Product name
Eptaplatin
Packaging
5mg
Price
$158
Updated
2021/12/16
Biosynth Carbosynth
Product number
FE22772
Product name
Eptaplatin
Packaging
50 mg
Price
$333
Updated
2021/12/16
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Eptaplatin Chemical Properties,Usage,Production

Description

SKI-2053R was launched in Korea for the treatment of patients with advanced gastric adenocarcinoma. It is a third generation platinum complex alkylating agent with less nephrotoxicity than cisplatin. In in vitro experiments, SKI-2053R was highly active against various cell lines including cisplatinresistant tumor cell lines. In mice implanted with L1210 cells, SKI-2053R showed activity comparable or superior to cisplatin or carboplatin. In mice implanted s.c. with human tumor xenograft KATO III (stomach adenocarcinoma), SKI-2053R achieved growth-inhibition rates comparable with those of cisplatin. General pharmacological studies in animals did not display any severe adverse effects on the different systems at antitumour doses. Pharmacokinetic studies after a single iv administration in rats demonstrated that the compound was extensively and rapidly distributed into all tissues except the CNS. In patients with unresectable or metastatic gastric adenocarcinoma, SKI-2053R was active without significant hematological toxicity. Phase III trials with SKI-2053R are currently ongoing for the treatment of various other cancers including lung, head and neck.

Chemical Properties

White Crystalline Powder

Originator

SK Pharma (Korea)

Uses

A coordination compound for treatment of cervix cancer.

brand name

Sunpla

Pharmaceutical Applications

heptaplatin is further examples of platinum-based agents being used in China and South Korea, respectively. Heptaplatin is used in South Korea to treat gastric cancer. It show the typical side effects such as myelosuppression and mild hepatotoxicity. its success is limited and has not led to approval in the EU or by the FDA.

Eptaplatin Preparation Products And Raw materials

Raw materials

Preparation Products

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Eptaplatin Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chembest Research Laboratories Limited
Tel
021-20908456-
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
5947
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35909
Advantage
56
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
1938
Advantage
70
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32358
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-2580635- ;0712-2580635
Email
1791901229@qq.com;1791901229@qq.com;
Country
China
ProdList
8924
Advantage
52
BOC Sciences
Email
info@bocsci.com
Country
United States
ProdList
21113
Advantage
65
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810- ;025-57798810-
Fax
025-57019371
Email
sales@sunlidabio.com;sales@sunlidabio.com
Country
China
ProdList
3756
Advantage
55
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10657
Advantage
60
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 QQ:3091977954
Fax
027-59420980
Email
dh.luna@whdhwy.com
Country
China
ProdList
4957
Advantage
58
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View Lastest Price from Eptaplatin manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Eptaplatin 146665-77-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Eptaplatin 146665-77-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Career Henan Chemical Co
Product
Eptaplatin 146665-77-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kgs
Release date
2020-01-28

146665-77-2, EptaplatinRelated Search:


  • SUNPLA
  • [sp-4-2-[4r-(2a,4a,5b)]]-[2-(1-methylethyl)-1,3-dioxolane-4,5-dimethanamine-n,n'][propanedioato(2-)-o,o']-platinum
  • heptaplatin
  • EPTAPLATIN
  • SKI 2053R
  • EPOXYPROGESTERONE
  • (SP-4-2)-[(4R,5R)-2-ISOPROPYL-1,3-DIOXOLANE-4,5-BIS(METHANAMINE)-N,N''][PROPANEDIOATO(2-)-O,O'']PLATINUM
  • (SP-4-2)-[(4R,5R)-2-(1-Methylethyl-1,3-dioxolane 4,5-dimethanamine-kN4,kN5][propanedioato(2-)-kO1,kO3]platinum
  • cis-[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane](malonate)platinum(II)
  • (SP-4-2)-[(4R,5R)-2-Isopropyl-1,3-dioxolane-4,5-
  • EPTAPLATIN, SUNPLA
  • Eptaplatin(Heptaplatin)
  • Eptaplatin(SKI-2053R)
  • Eptaplatin, >=98%
  • (SP-4-2)-[(4R,5R
  • cis-[(4R,5R)-2-Isopropyl-1,3-dioxolane-4,5-bis(methylamine)-N,N'][malonato(2-)-O,O']platinum
  • Cis-(1,3-malanato)-[(4R,5R)-4,5-bis(aminomethyl)-2isopropyl-1,3-dioxolane]platinum(II)
  • cis-{Pt(II)[(4R,5R)-4,5-bis(aminomethyl)-2-isopropyl-1,3-dioxolane](3-acetoxyl-cyclobutane-1,1-dicarboxylato)}
  • 9-propan-2-yl-8,10-dioxa-3,5-diaza-4$l^{4}-platinabicyclo[5.3.0]deca-3,4-diene
  • 146665-77-2
  • C11H20N2O6Pt
  • C8H18N2O2C3H2O4Pt
  • C11H16N2O6Pt
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Heterocyclic Compounds
  • Anticancer