Nedaplatin

Product Name: Nedaplatin
CAS No.: 95734-82-0
Chemical Name: Nedaplatin
Synonyms: 254-s;Aqupla;Nedaplait;NEDAPLATIN;NSC 375101D;Nedaplatin, >=99%;Nedaplatin USP/EP/BP;Nedaplatin (NSC 375101D);cis-diammine(glycolato)platinum(ii);(glycolato-o,o')diammineplatinum(ii)
CBNumber: CB5127746
Molecular Formula: C2H6N2O3Pt
Formula Weight: 301.17
MOL File: 95734-82-0.mol

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Nedaplatin Property

storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: H2O : 13.6 mg/mL (44.86 mM; Need ultrasonic and warming; DMSO can inactivate Nedaplatin's activity)DMF : < 1 mg/mL (insoluble; DMSO can inactivate Nedaplatin's activity)
form: Powder
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29001
Product name: Nedaplatin
Packaging: 25mg
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 29001
Product name: Nedaplatin
Packaging: 250mg
Price: $671
Updated: 2024/03/01

Cayman Chemical

Product number: 29001
Product name: Nedaplatin
Packaging: 50mg
Price: $152
Updated: 2024/03/01

Cayman Chemical

Product number: 29001
Product name: Nedaplatin
Packaging: 100mg
Price: $287
Updated: 2024/03/01

TRC

Product number: N388803
Product name: Nedaplatin
Packaging: 10mg
Price: $130
Updated: 2021/12/16

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Nedaplatin Chemical Properties,Usage,Production

Description

Nedaplatin, a novel second generation platinum complex, was marketed in Japan for the treatment of a variety of cancers including: head and neck, small-cell and non-small cell lung, oesophageal, prostatic, testicular, ovarian, cervical, bladder, and uterine cancers. Platinum anticancer agents, prototyped by cisplatin, have been reported to be hydrolyzed to the mono- or diaquated species of diamine platinum which react with nucleophilic sites on DNA to cause intrastrand and interstrand crosslinks and DNA-protein crosslinks, which result in cytotoxicity. Nedaplatin was reportedly more active than cisplatin against several solid tumors while sharing less nephro- and gastrointestinal toxicity to cisplatin in viva The minimal renal toxicity displayed by nedaplatin allows its use in patients with deteriorated renal function.

Originator

Shionogi (Japan)

Uses

anticancer

Uses

Nedaplatin is a platinum complex that has potent antineoplatic activity.

brand name

Aqupla

Pharmaceutical Applications

Nedaplatin, cis-diammineglycolatoplatinum(II), is structurally similar to carboplatin. The chemical structure consists of a central platinum(II) atom with two cis-ammonia groups as nonleaving groups and – in contrast to carboplatin – the dianionic form of glycolic acid as the leaving group. Nedaplatin has been approved for the clinical use in the Japanese market for the treatment of head and neck, testicular, ovarian, lung and cervical cancer. It is typically administered by IV injection and its dose-limiting side effect is myelosuppression.

Nedaplatin Preparation Products And Raw materials

Raw materials

Preparation Products

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Nedaplatin Suppliers

China 183 Europe 2 Germany 1 India 1 United Kingdom 6 United States 23 Global 216

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 8415
Advantage: 55

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8843
Advantage: 52

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 9387
Advantage: 52

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View Lastest Price from Nedaplatin manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Nedaplatin 95734-82-0
Price: US $0.00/g
Min. Order: 1g
Purity: 98%-102%
Supply Ability: 100g
Release date: 2022-12-29

Zhuozhou Wenxi import and Export Co., Ltd

Product: Nedaplatin 95734-82-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Nedaplatin 95734-82-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

95734-82-0, NedaplatinRelated Search:

Platinum (II), diammineoxalato-, cis- Adriamycin Gemcitabine Cytarabine Fluorescein Sodium Dexrazoxane Zoledronic acid Carboplatin PHT-427 Dasatinib CHIR-99021 Sofosbuvir BEZ235 (NVP-BEZ235, Dactolisib) Cisplatin Miboplatin Oxaliplatin Nedaplatin NEDAPLATIN

(glycolato-o,o')diammineplatinum(ii)

cis-diammine(glycolato)platinum(ii)

NEDAPLATIN

254-s

Aqupla

cis-diamine-glycolate-O,O'-platinum(II)

o(sup2))-diammine(hydroxyacetato(2-)-o(sup1(sp-4-3)-platinu

Nedaplait

o(sup 2))- diammine(hydroxyacetato(2-)-o(sup 1 (sp-4-3)-platinu (glycolato-o,o')diammineplatinum(ii) 254-s cis-diammine(glycolato)platinum(ii) nedaplatin nsc 375101d

2,2-diaMino-1,3-dioxa-2-platinacyclopentan-4-one

PlatinuM,diaMMine[(hydroxy-kO)acetato(2-)-kO]-, (SP-4-3)-

(SP-4-3)-diammine[2-(hydroxy-κO)acetato(2-)-κO]-platinum

Nedaplatin, >=99%

cis-Diammine(glycolato(2-)O,O')platinum

Cis-diammine-glycoloato-O,O'-platinum(II)

platinum(2+) azanide- hydroxyacetic acid(1:2:1)

NSC 375101D

Nedaplatin USP/EP/BP

Nedaplatin (NSC 375101D)

95734-82-0

C2H4N2O3Pt

C2H8N2O3Pt

C2H2O3Pt2H3N

Inhibitors

Anticancer

Anticancer Platinum Agent