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Nedaplatin

Product Name
Nedaplatin
CAS No.
95734-82-0
Chemical Name
Nedaplatin
Synonyms
254-s;Aqupla;Nedaplait;NEDAPLATIN;NSC 375101D;Nedaplatin, >=99%;Nedaplatin USP/EP/BP;Nedaplatin (NSC 375101D);cis-diammine(glycolato)platinum(ii);(glycolato-o,o')diammineplatinum(ii)
CBNumber
CB5127746
Molecular Formula
C2H6N2O3Pt
Formula Weight
301.17
MOL File
95734-82-0.mol
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Nedaplatin Property

storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
H2O : 13.6 mg/mL (44.86 mM; Need ultrasonic and warming; DMSO can inactivate Nedaplatin's activity)DMF : < 1 mg/mL (insoluble; DMSO can inactivate Nedaplatin's activity)
form 
Powder
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29001
Product name
Nedaplatin
Packaging
25mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
29001
Product name
Nedaplatin
Packaging
250mg
Price
$671
Updated
2024/03/01
Cayman Chemical
Product number
29001
Product name
Nedaplatin
Packaging
50mg
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
29001
Product name
Nedaplatin
Packaging
100mg
Price
$287
Updated
2024/03/01
TRC
Product number
N388803
Product name
Nedaplatin
Packaging
10mg
Price
$130
Updated
2021/12/16
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Nedaplatin Chemical Properties,Usage,Production

Description

Nedaplatin, a novel second generation platinum complex, was marketed in Japan for the treatment of a variety of cancers including: head and neck, small-cell and non-small cell lung, oesophageal, prostatic, testicular, ovarian, cervical, bladder, and uterine cancers. Platinum anticancer agents, prototyped by cisplatin, have been reported to be hydrolyzed to the mono- or diaquated species of diamine platinum which react with nucleophilic sites on DNA to cause intrastrand and interstrand crosslinks and DNA-protein crosslinks, which result in cytotoxicity. Nedaplatin was reportedly more active than cisplatin against several solid tumors while sharing less nephro- and gastrointestinal toxicity to cisplatin in viva The minimal renal toxicity displayed by nedaplatin allows its use in patients with deteriorated renal function.

Originator

Shionogi (Japan)

Uses

anticancer

Uses

Nedaplatin is a platinum complex that has potent antineoplatic activity.

brand name

Aqupla

Pharmaceutical Applications

Nedaplatin, cis-diammineglycolatoplatinum(II), is structurally similar to carboplatin. The chemical structure consists of a central platinum(II) atom with two cis-ammonia groups as nonleaving groups and – in contrast to carboplatin – the dianionic form of glycolic acid as the leaving group. Nedaplatin has been approved for the clinical use in the Japanese market for the treatment of head and neck, testicular, ovarian, lung and cervical cancer. It is typically administered by IV injection and its dose-limiting side effect is myelosuppression.

Nedaplatin Preparation Products And Raw materials

Raw materials

Preparation Products

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Nedaplatin Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6013
Advantage
61
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7508
Advantage
55
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2127
Advantage
70
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8850
Advantage
52
Shanghai Sphchem Co., Ltd.
Tel
21-21-56491756 13512199871
Fax
021-5649-1756
Email
sales@panhongchem.com
Country
China
ProdList
4001
Advantage
55
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View Lastest Price from Nedaplatin manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Nedaplatin 95734-82-0
Price
US $0.00/g
Min. Order
1g
Purity
98%-102%
Supply Ability
100g
Release date
2022-12-29
Zhuozhou Wenxi import and Export Co., Ltd
Product
Nedaplatin 95734-82-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Nedaplatin 95734-82-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

95734-82-0, NedaplatinRelated Search:


  • (glycolato-o,o')diammineplatinum(ii)
  • cis-diammine(glycolato)platinum(ii)
  • NEDAPLATIN
  • 254-s
  • Aqupla
  • cis-diamine-glycolate-O,O'-platinum(II)
  • o(sup2))-diammine(hydroxyacetato(2-)-o(sup1(sp-4-3)-platinu
  • Nedaplait
  • o(sup 2))- diammine(hydroxyacetato(2-)-o(sup 1 (sp-4-3)-platinu (glycolato-o,o')diammineplatinum(ii) 254-s cis-diammine(glycolato)platinum(ii) nedaplatin nsc 375101d
  • 2,2-diaMino-1,3-dioxa-2-platinacyclopentan-4-one
  • PlatinuM,diaMMine[(hydroxy-kO)acetato(2-)-kO]-, (SP-4-3)-
  • (SP-4-3)-diammine[2-(hydroxy-κO)acetato(2-)-κO]-platinum
  • Nedaplatin, >=99%
  • cis-Diammine(glycolato(2-)O,O')platinum
  • Cis-diammine-glycoloato-O,O'-platinum(II)
  • platinum(2+) azanide- hydroxyacetic acid(1:2:1)
  • NSC 375101D
  • Nedaplatin USP/EP/BP
  • Nedaplatin (NSC 375101D)
  • 95734-82-0
  • C2H4N2O3Pt
  • C2H8N2O3Pt
  • C2H2O3Pt2H3N
  • Inhibitors
  • Anticancer
  • Anticancer Platinum Agent