ChemicalBook > CAS DataBase List > 5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone

5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone

Product Name
5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone
CAS No.
1268140-15-3
Chemical Name
5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone
Synonyms
5,7,3'-TRIHYDROXY-4'-METHOXY-8-P;5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone;(2S)-5,7,3'-trihydroxy-4'-methoxy-8-(3''-methylbut-2''-enyl)-flavonone;5,7-Dihydroxy-2-(3-hydroxy-4-Methoxyphenyl)-8-(3-Methylbut-2-en-1-yl)chroMan-4-one;(2S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-, (2S)-
CBNumber
CB22566539
Molecular Formula
C21H22O6
Formula Weight
370.4
MOL File
1268140-15-3.mol
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5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone Property

Boiling point:
616.0±55.0 °C(Predicted)
Density 
1.308±0.06 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
7.67±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom
Product number
CFN97833
Product name
5,7,3'-Trihydroxy-4'-methoxy-8-prenylflavanone
Purity
≥98%
Packaging
5mg
Price
$553
Updated
2021/12/16
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5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone Chemical Properties,Usage,Production

Uses

5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone (compound 1), a flavonoid, is a potent ABCG2 inhibitor with an IC50 of 6.6 μM[1].

Definition

ChEBI: A trihydroxyflavanone that is hesperetin substituted by a prenyl group at position 8. Isolated from Macaranga conifera, it exhibits inhibitory activity against breast cancer resistance protein.

References

[1] Muhammad Ali Versiani, et al. Flavonoids from Eight Tropical Plant Species That Inhibit the Multidrug Resistance Transporter ABCG2. J Nat Prod. 2011 Feb 25;74(2):262-6. DOI:10.1021/np100797y

5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone Preparation Products And Raw materials

Raw materials

Preparation Products

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5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone Suppliers

Chembest Research Laboratories Limited
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1268140-15-3, 5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanoneRelated Search:


  • 5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone
  • (2S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
  • 5,7-Dihydroxy-2-(3-hydroxy-4-Methoxyphenyl)-8-(3-Methylbut-2-en-1-yl)chroMan-4-one
  • 5,7,3'-TRIHYDROXY-4'-METHOXY-8-P
  • (2S)-5,7,3'-trihydroxy-4'-methoxy-8-(3''-methylbut-2''-enyl)-flavonone
  • 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-, (2S)-
  • 1268140-15-3