Methyl 2,3-dichloropropionate

Product Name: Methyl 2,3-dichloropropionate
CAS No.: 3674-09-7
Chemical Name: Methyl 2,3-dichloropropionate
Synonyms: 2,3-dichloropropionate;METHYL-A,B-DICHLOROPROPIONATE;METHYL 2,3-DICHLOROPROPIONATE;Methyl 2,3-dichloropropanoate;Methyl2,3-Dichloropropionate>Methyl 2,3-dichloropropionate,98%;METHYL ALPHA,BETA-DICHLOROPROPIONATE;2,3-dichloro-propanoicacimethylester;2,3-Dichloropropionic Acid Methyl Este;2,3-DICHLOROPROPIONIC ACID METHYL ESTER
CBNumber: CB2257329
Molecular Formula: C4H6Cl2O2
Formula Weight: 157
MOL File: 3674-09-7.mol

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Methyl 2,3-dichloropropionate Property

Boiling point:: 52-55 °C/2 mmHg (lit.)
Density: 1.325 g/mL at 25 °C (lit.)
refractive index: n20/D 1.453(lit.)
Flash point:: 145 °F
storage temp.: Store below +30°C.
solubility: Soluble in ether, acetone, ethanol.
color: Colorless to Almost colorless
BRN: 1701891
InChI: InChI=1S/C4H6Cl2O2/c1-8-4(7)3(6)2-5/h3H,2H2,1H3
InChIKey: OFHMODDLBXETIK-UHFFFAOYSA-N
SMILES: C(OC)(=O)C(Cl)CCl
CAS DataBase Reference: 3674-09-7(CAS DataBase Reference)
NIST Chemistry Reference: Propanoic acid, 2,3-dichloro-, methyl ester(3674-09-7)
EPA Substance Registry System: Propanoic acid, 2,3-dichloro-, methyl ester (3674-09-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38-10
Safety Statements: 23-24/25-37/39-26-16
RIDADR: 1993
WGK Germany: 3
TSCA: Yes
HazardClass: 8
PackingGroup: III
HS Code: 29159000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H227Combustible liquid

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.18319
Product name: Methyl 2,3-dichloropropionate
Purity: for synthesis
Packaging: 10ml
Price: $44.2
Updated: 2024/03/01

TCI Chemical

Product number: D0408
Product name: Methyl 2,3-Dichloropropionate
Purity: >95.0%(GC)
Packaging: 10g
Price: $26
Updated: 2024/03/01

Alfa Aesar

Product number: B21993
Product name: Methyl 2,3-dichloropropionate, 98%
Packaging: 25g
Price: $46.65
Updated: 2024/03/01

Alfa Aesar

Product number: B21993
Product name: Methyl 2,3-dichloropropionate, 98%
Packaging: 100g
Price: $102.65
Updated: 2024/03/01

Alfa Aesar

Product number: B21993
Product name: Methyl 2,3-dichloropropionate, 98%
Packaging: 500g
Price: $396.65
Updated: 2024/03/01

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Methyl 2,3-dichloropropionate Chemical Properties,Usage,Production

Chemical Properties

clear colorless to slightly yellow liquid

Uses

Methyl 2,3-dichloropropionate can be used to produce 2-chloro-acrylic acid methyl ester at Heating. It is used as pharmaceutical intermediate.

Application

Methyl 2,3-Dichloropropanoate is a useful reagent in preparation of oxidative fragmentation and coupling of catharanthine analogs to vindoline.

Synthesis

Preparation of Methyl 2,3-dichloropropanoate:
Methyl acrylate (2366 g, 27.5 mol) and dimethylformamide (DMF) (40 g, 0.55 mol) was placed in a 3-liter three necked flask fitted with a stirrer, thermometer, inlet tube and gas trap. Chlorine (950 g, 0.48 mol) was passed into the methyl acrylate rapidly over a period of ten hours while the temperature was kept below 40°C. Reaction progress was monitored by gas chromatography (GC). When it seemed that 50 percent of chlorine was consumed, the reaction was stopped. The reaction mass was taken for distillation to separate methylacrylate and Methyl 2,3-dichloropropanoate. The contents were subjected to vacuum distillation. Methyl 2,3-dichloropropanoate was collected distilling at 70°C with 15mm.Yield (%):77.2, Purity (%) = 98.

Methyl 2,3-dichloropropionate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 2,3-dichloropropionate Suppliers

Americas 1 Belgium 1 China 128 Europe 2 Germany 4 India 2 Japan 4 Switzerland 1 United Kingdom 6 United States 14 Global 163

Wuhan kemike Biomedical Technology Co., Ltd

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Nanjing Winsome Chemical Limited

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HANGZHOU LOOP BIOTECH CO., LTD.

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Shandong Mopai Biotechnology Co., Ltd

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J & K SCIENTIFIC LTD.

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Meryer (Shanghai) Chemical Technology Co., Ltd.

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3B Pharmachem (Wuhan) International Co.,Ltd.

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Country: China
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Alfa Aesar

Tel: 400-6106006
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Email: saleschina@alfa-asia.com
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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
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ProdList: 24529
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Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44688
Advantage: 61

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View Lastest Price from Methyl 2,3-dichloropropionate manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Methyl 2,3-dichloropropionate 3674-09-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-11-28

Shaanxi Dideu Medichem Co. Ltd

Product: Methyl 2,3-dichloropropionate 3674-09-7
Price: US $1.00/Kg
Min. Order: 1Kg
Purity: 98%
Supply Ability: 20T
Release date: 2024-07-19

Henan Fengda Chemical Co., Ltd

Product: Methyl 2,3-dichloropropanoate 3674-09-7
Price: US $200.00-1.00/KG
Min. Order: 1KG
Purity: 99%, 99.5% Sublimated
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-30

3674-09-7, Methyl 2,3-dichloropropionateRelated Search:

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METHYL 2,3-DICHLOROPROPIONATE

METHYL-A,B-DICHLOROPROPIONATE

METHYL ALPHA,BETA-DICHLOROPROPIONATE

2,3-DICHLOROPROPIONIC ACID METHYL ESTER

2,3-dichloro-propanoicacimethylester

Methyl 2,3-dichloropropanoate

Propionic acid, 2,3-dichloro-, methyl ester

METHYL-2,3-DICHLOROPROPIONATE, 1000MG, N EAT

Methyl 2,3-dichloropropionate, tech., 70%

Propanoic acid, 2,3-dichloro-, methyl ester

2,3-dichloro-propanoic acid methyl ester

Methyl 2,3-dichloropropionate,98%

Methyl 2,3-dichloropropionate,70%,tech.

Methyl 2,3-dichloropropionate, tech., 70% 25ML

METHYL 2,3-DICHLOROPROPIONATE FOR SYNTHE

Methyl2,3-Dichloropropionate&gt

2,3-dichloropropionate

Propanoic acid, 2,3-dichloro-, methyl ester (9CI, ACI)

2,3-dichloro-Propanoic acid methyl ester (9CI ACI)

2,3-Dichloropropionic Acid Methyl Este

3674-09-7

648-19-2

674-09-7

3674-09-07

ClCH2CHClCOOCH3

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