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ChemicalBook > CAS DataBase List > 2-AMINO-4,6-DICHLOROBENZOIC ACID

2-AMINO-4,6-DICHLOROBENZOIC ACID

Uses
Product Name
2-AMINO-4,6-DICHLOROBENZOIC ACID
CAS No.
20776-63-0
Chemical Name
2-AMINO-4,6-DICHLOROBENZOIC ACID
Synonyms
BUTTPARK 49\07-45;2-AMINO-4,6-DICHLOROBENZOIC ACID;Benzoic acid, 2-amino-4,6-dichloro-;2-AMINO-4,6-DICHLOROBENZOIC ACID FOR SYN;2-Amino-4,6-dichlorobenzoic acid for synthesis;2-AMINO-4,6-DICHLOROBENZOIC ACID ISO 9001：2015 REACH
CBNumber
CB2258159
Molecular Formula
C7H5Cl2NO2
Formula Weight
206.03
MOL File
20776-63-0.mol
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2-AMINO-4,6-DICHLOROBENZOIC ACID Property

Melting point:
178.0-178.5 °C (decomp)
Boiling point:
375.2±42.0 °C(Predicted)
Density 
1.607±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
1.25g/l
pka
3.42±0.25(Predicted)
form 
solid
Appearance
Light yellow to light brown Solid
PH
2.3 (H2O, 20℃)
Water Solubility 
1.25g/L
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Safety

Risk Statements 
36
Safety Statements 
26
WGK Germany 
WGK 3 highly water endangering
HS Code 
2922 49 85
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.15106
Product name
2-Amino-4,6-dichlorobenzoic acid
Purity
for synthesis
Packaging
10g
Price
$605
Updated
2025/07/31
TRC
Product number
A597153
Product name
2-Amino-4,6-dichlorobenzoic acid
Packaging
50mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA140841
Product name
2-Amino-4,6-dichlorobenzoic acid
Packaging
100mg
Price
$55
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA140841
Product name
2-Amino-4,6-dichlorobenzoic acid
Packaging
250mg
Price
$110
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA140841
Product name
2-Amino-4,6-dichlorobenzoic acid
Packaging
500mg
Price
$190
Updated
2021/12/16
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2-AMINO-4,6-DICHLOROBENZOIC ACID Chemical Properties,Usage,Production

Uses

2-Amino-4,6-dichlorobenzoic acid is a carboxylic acid derivative, which is mainly used in the synthesis of pharmaceutical intermediates.

Synthesis

18711-15-4

20776-63-0

General procedure for the synthesis of 2-amino-4,6-dichlorobenzoic acid from 4,6-dichlorodihydroindole-2,3-dione: 3) Preparation of intermediate I-3; At room temperature, Intermediate I-2 (5.0 g, 23.1 mmol) prepared from Example I (2) of the above isolation was dissolved in 75 mL of 1N NaOH (aq), and hydrogen peroxide (28% v/v, 10 mL) was added in batches. The reaction mixture was stirred for 2 hours and then filtered to remove the insoluble dark brown solid. Subsequently, the filtrate was carefully acidified with hydrochloric acid to pH 2. The yellow precipitate formed was collected, washed with water and dried under vacuum. The target compound 2-amino-4,6-dichlorobenzoic acid (3.90 g, 82% yield) was obtained as an ivory colored solid by recrystallization from benzene. TLC Rf = 0.1 (EtOAc:hexane = 1:1); Melting point 188-189°C; 1H NMR (DMSO-d6) δ 6.76 (d, J=1.9Hz, 1H, ArH), 6.85 (d, J=1.9Hz, 1H, ArH); MS (EI) m/e 206 [M+], 162 [M+-CO2].

References

[1] Patent: US2006/84676, 2006, A1. Location in patent: Page/Page column 7
[2] Patent: EP1650190, 2006, A1. Location in patent: Page/Page column 10
[3] Patent: WO2008/4716, 2008, A1. Location in patent: Page/Page column 25-26
[4] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 2, p. 738 - 743
[5] Patent: US2009/203708, 2009, A1. Location in patent: Page/Page column 8

2-AMINO-4,6-DICHLOROBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-4,6-DICHLOROBENZOIC ACID Suppliers

China 48 Germany 2 India 1 Russia 1 Ukraine 1 United Kingdom 2 United States 6 Global 61
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Butt Park Ltd.
Tel
--
Fax
--
Email
113707.50@compuserve.com
Country
United Kingdom
ProdList
6078
Advantage
30
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View Lastest Price from 2-AMINO-4,6-DICHLOROBENZOIC ACID manufacturers

Career Henan Chemical Co
Product
2-AMINO-4,6-DICHLOROBENZOIC ACID 20776-63-0
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2020-01-12

20776-63-0, 2-AMINO-4,6-DICHLOROBENZOIC ACIDRelated Search:

2-AMINO-4,6-DICHLOROBENZOIC ACID 4-Amino-3,5-dichlorobenzoic acid methyl ester 2-AMINO-3,5-DICHLOROBENZOIC ACID 4-AMINO-3,5-DICHLOROBENZOIC ACID, 98+%,4-AMINO-3,5-DICHLOROBENZOIC ACID 2-AMINO-3,6-DICHLOROBENZOIC ACID 3-AMINO-2,5-DICHLOROBENZOIC ACID,250MG,&,3-AMINO-2,5-DICHLOROBENZOIC ACID 2-Amino-6-chlorobenzoic acid 2-AMINO-5,6-DICHLOROBENZOIC ACID Benzoic acid, 5-amino-2,3-dichloro- (9CI) 3-AMINO-2,5-DICHLOROBENZOIC ACID METHYL ESTER,CHLORAMBEN:3-AMINO-2,5-DICHLOROBENZOIC ACID 3-AMINO-4,5-DICHLOROBENZOIC ACID,2-AMINO-4,5-DICHLOROBENZOIC ACID (2-AMINO-6-CHLORO-PHENYL)-METHANOL 4-AMINO-3,5-DICHLOROBENZOIC ACID ETHYL ESTER 3-Amino-2,5-dichlorobenzoic acid ammonium salt 5-AMINO-2,4-DICHLOROBENZOIC ACID 3-Amino-2,6-dichlorobenzoic acid 4-Amino-2,3-dichlorobenzoic acid 4-amino-2,6-dichlorobenzoic acid

  • 2-AMINO-4,6-DICHLOROBENZOIC ACID
  • BUTTPARK 49\07-45
  • 2-AMINO-4,6-DICHLOROBENZOIC ACID FOR SYN
  • 2-Amino-4,6-dichlorobenzoic acid for synthesis
  • Benzoic acid, 2-amino-4,6-dichloro-
  • 2-AMINO-4,6-DICHLOROBENZOIC ACID ISO 9001：2015 REACH
  • 20776-63-0