Ertugliflozin

Product Name: Ertugliflozin
CAS No.: 1210344-57-2
Chemical Name: Ertugliflozin
Synonyms: Ertugliflozin;(1S,2S,3S,4R,5S)-(2,3,4-TRIS-BENZYLOXY-5-(4-CHLORO-3-(4-ETHOXY-BENZYL)-PHENYL)-68-DIOXA-BICYCLO(3.2.1)OCT-1-YL)-METHANOL;(1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol;(1S,2S,3S,4R,5S)-5-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol;1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-beta-L-idopyranose PF-04971729(Ertugliflozin);CS-186;MK-8835;PF-04971729;Epagliflozin;PF 04971729-00
CBNumber: CB22583105
Molecular Formula: C22H25ClO7
Formula Weight: 436.88
MOL File: 1210344-57-2.mol

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Ertugliflozin Property

Melting point:: 65 - 66oC
Boiling point:: 630.5±55.0 °C(Predicted)
Density: 1.455
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 12.95±0.70(Predicted)
form: Solid
color: White to Off-White
InChIKey: MCIACXAZCBVDEE-RDZQEHASNA-N
SMILES: [C@@]12(C3C=CC(Cl)=C(CC4C=CC(OCC)=CC=4)C=3)OC[C@@](CO)([C@@H](O)[C@H](O)[C@H]1O)O2 |&1:0,20,23,25,27,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 21507
Product name: Ertugliflozin
Purity: ≥98%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 21507
Product name: Ertugliflozin
Purity: ≥98%
Packaging: 5mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 21507
Product name: Ertugliflozin
Purity: ≥98%
Packaging: 10mg
Price: $283
Updated: 2024/03/01

Cayman Chemical

Product number: 21507
Product name: Ertugliflozin
Purity: ≥98%
Packaging: 25mg
Price: $618
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: INB0001388
Product name: (1R,2S,3S,4R,5R)-5-(4-CHLORO-3-(4-ETHOXYBENZYL)PHENYL)-1-(HYDROXYMETHYL)-6,8-DIOXABICYCLO[3.2.1]OCTANE-2,3,4-TRIOL
Purity: 95.00%
Packaging: 0.025G
Price: $671
Updated: 2021/12/16

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Ertugliflozin Chemical Properties,Usage,Production

Uses

Ertugliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor used to treat type 2 diabetes.

Definition

ChEBI: Ertugliflozin is a diarylmethane.

Application

Ertugliflozin is a medication prescribed by veterinarians to help control insulin (blood sugar) levels in horses and ponies with insulin dysregulation (ID), equine metabolic syndrome (EMS), refractory hyperinsulinemia (high blood sugar), and hyperinsulinemic-associated laminitis (HAL), especially for horses that don't respond to changes in diet or other accepted management practices for metabolic syndromes. Ertugliflozin is not FDA-approved for equine use. It falls into the sodium-glucose co-transport-2 (SGLT2) inhibitors category and is administered orally at 0.05?mg/kg once daily for at least 30?days.

Mode of action

Ertugliflozin works by inhibiting the SGLT2 protein, which aids in the reabsorption of glucose in the kidneys, leading to excretion of more glucose through urine. Once daily doses of ertugliflozin have been shown to: Lower blood sugar levels, Correct insulin to normal or near-normal levels, and Reduce abnormal fat pads.

Ertugliflozin Preparation Products And Raw materials

Raw materials

Preparation Products

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Ertugliflozin Suppliers

China 191 India 8 United States 13 Global 212

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
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BOC Sciences

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Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Musechem

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Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

InvivoChem

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Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
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Cckinase, Inc.

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Email: sales@cckinase.com
Country: United States
ProdList: 2738
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BOC Sciences

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Country: United States
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Protheragen-ING

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Aladdin Scientific

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TargetMol Chemicals Inc.

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ApexBio Technology

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Country: United States
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Cayman Chemical Company

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Country: United States
ProdList: 6213
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Matrix Scientific

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ProdList: 6632
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View Lastest Price from Ertugliflozin manufacturers

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Product: Ertugliflozin 1210344-57-2
Price: US $0.00/g
Min. Order: 1g
Purity: More Than 99%
Supply Ability: 100kg/Month
Release date: 2024-12-12

Baoji Guokang Bio-Technology Co., Ltd.

Product: PF-04971729 1210344-57-2
Price: US $412.00/g/Bag
Min. Order: 1g
Purity: 99%
Supply Ability: 1kg
Release date: 2021-06-04

Nanjing Fred Technology Co., Ltd

Product: Ertugliflozin 1210344-57-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%, Single impurity＜0.1
Supply Ability: 1 ton
Release date: 2024-01-04

1210344-57-2, ErtugliflozinRelated Search:

Atazanavir Vincristine Rivaroxaban Pioglitazone hydrochloride VIGABATRIN Lorlatinib (PF-06463922) (2S,3R,4S,5S,6R)-2-(3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxyMethyl)-2-Methoxy-2H-pyran-3,4,5-triol 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Canagliflozin heMihydrate 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone Ipragliflozin 1-Chloro-2-(4-ethoxybenzyl)-4-iodobenzene 2,3,4,6-TETRA-O-PIVALOYL-ALPHA-D-GLUCOPYRANOSYL BROMIDE Dapagliflozin Canagliflozin Empagliflozin Vildagliptin TOFOGLIFLOZIN

PF-04971729/PF04971729

1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-beta-L-idopyranose

Ertugliflozin, >=98%

Ertugliflozin : PF 04971729-00

Leuco methylthioninium

(1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

Ertugliflozin Base

(1S,2S,3S,4R,5S)-(2,3,4-TRIS-BENZYLOXY-5-(4-CHLORO-3-(4-ETHOXY-BENZYL)-PHENYL)-68-DIOXA-BICYCLO(3.2.1)OCT-1-YL)-METHANOL

PF 04971729-00

PF-04971729/Ertugliflozin

1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-beta-L-idopyranose PF-04971729(Ertugliflozin)

Ertugliflozin MK-8835

PF-04971729

Ertugliflozin

Ertugliflozin/PF-04971729

(1S,2S,3S,4R,5S)-5-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-

CS-186

PF04971729;PF 04971729 (ERTUGLIFLOZIN)

ERTUGLIFLOZIN;PF04971729;PF 04971729

MK-8835

1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose

PF-04971729 USP/EP/BP

Ertugliflozin D4

MK-8835， PF-04971729

Ertugliflozin Intermediate PF05

Epagliflozin

Empagliflozin Impurity 225

Leuco methylthioninium Impurity

Ertugliflozin, 10 mM in DMSO

1210344-57-2

C22H25ClO7

C22H25CIO7

API