ChemicalBook > CAS DataBase List > Furowanin A

Furowanin A

Product Name
Furowanin A
CAS No.
911004-72-3
Chemical Name
Furowanin A
Synonyms
Furowanin A;6-(3,4-Dihydroxyphenyl)-2,3-dihydro-4-hydroxy-2-(1-hydroxy-1-methylethyl)-9-(3-methyl-2-buten-1-yl)-5H-furo[3,2-g][1]benzopyran-5-one;5H-Furo[3,2-g][1]benzopyran-5-one, 6-(3,4-dihydroxyphenyl)-2,3-dihydro-4-hydroxy-2-(1-hydroxy-1-methylethyl)-9-(3-methyl-2-buten-1-yl)-
CBNumber
CB22611194
Molecular Formula
C25H26O7
Formula Weight
438.47
MOL File
911004-72-3.mol
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Furowanin A Property

solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom
Product number
CFN97918
Product name
FurowaninA
Packaging
5mg
Price
$553
Updated
2021/12/16
Crysdot
Product number
CD32000138
Product name
FurowaninA
Purity
95+%
Packaging
5mg
Price
$860
Updated
2021/12/16
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Furowanin A Chemical Properties,Usage,Production

Description

Furowanin A shows significant cytotoxicity against HL-60 cells. Furowanin A induces that Caspase-9 and caspase-3 inhibitors suppresses apoptosis.

Uses

Furowanin A is a flavonoid with anti-neoplastic effects. Furowanin A inhibits STAT3/Mcl-1 axis to suppress proliferation, block cell cycle progression, induce apoptosis and promote autophagy. Furowanin A potently inhibits colorectal cancer (CRC) cells[1].

target

Caspase

IC 50

Mcl-1; STAT3

References

[1] Ma Z, et al. Furowanin A-induced autophagy alleviates apoptosis and promotes cell cycle arrest via inactivation STAT3/Mcl-1 axis in colorectal cancer. Life Sci. 2019 Feb 1;218:47-57. DOI:10.1016/j.lfs.2018.12.027

Furowanin A Preparation Products And Raw materials

Raw materials

Preparation Products

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Furowanin A Suppliers

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911004-72-3, Furowanin ARelated Search:

(4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one alpha-Cyperone beta-Eudesmol MOSLOFLAVONE hydroxygenkwanin alpha-Terpineol Artemether 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Hydroxyecdysone beta-Sitosterol

  • 6-(3,4-Dihydroxyphenyl)-2,3-dihydro-4-hydroxy-2-(1-hydroxy-1-methylethyl)-9-(3-methyl-2-buten-1-yl)-5H-furo[3,2-g][1]benzopyran-5-one
  • Furowanin A
  • 5H-Furo[3,2-g][1]benzopyran-5-one, 6-(3,4-dihydroxyphenyl)-2,3-dihydro-4-hydroxy-2-(1-hydroxy-1-methylethyl)-9-(3-methyl-2-buten-1-yl)-
  • 911004-72-3