PFI-1

Product Name: PFI-1
CAS No.: 1403764-72-6
Chemical Name: PFI-1
Synonyms: PFI-1;CS-709;PFI-1cas;PF-6405761;PFI 1;PFI1;PF-06405761;PFI-1 USP/EP/BP;PFI-1 (PF-6405761);PFI-1 (PF-06405761);PFI-1;PFI-1;PFI 1;PFI1
CBNumber: CB22655765
Molecular Formula: C16H17N3O4S
Formula Weight: 347.39
MOL File: 1403764-72-6.mol

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PFI-1 Property

storage temp.: Sealed in dry,2-8°C
solubility: DMSO: ≥10mg/mL
form: powder
color: white to beige

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0352
Product name: PFI-1
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $122
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0352
Product name: PFI-1
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $393
Updated: 2024/03/01

Cayman Chemical

Product number: 11155
Product name: PFI-1
Purity: ≥98%
Packaging: 1mg
Price: $38
Updated: 2024/03/01

Cayman Chemical

Product number: 11155
Product name: PFI-1
Purity: ≥98%
Packaging: 5mg
Price: $104
Updated: 2024/03/01

Cayman Chemical

Product number: 11155
Product name: PFI-1
Purity: ≥98%
Packaging: 10mg
Price: $166
Updated: 2024/03/01

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PFI-1 Chemical Properties,Usage,Production

Description

PFI 1 is a BET bromodomain inhibitor that exhibits inhibitory activity at BRD2 and BRD4. PFI-1 is a selective BET bromodomain inhibitor with activity at BRD2 (IC50 = 98 nM) and BRD4 (IC50 = 220 nM). PFI 1 induces apoptosis and G1 cell cycle arrest in BET inhibitor-sensitive cell lines (MV4;11). PFI 1 also downregulates Aurora B expression in MV4;11 cells.

Uses

PFI-1 is used as a selective protein interaction inhibitor targetting BET bromodomains, used as regulators required for efficient expression of several growth promoting and anti-apoptotic genes.

Definition

ChEBI: 2-methoxy-N-(3-methyl-2-oxo-1,4-dihydroquinazolin-6-yl)benzenesulfonamide is a member of quinazolines.

storage

Store at RT

PFI-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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PFI-1 Suppliers

Canada 1 China 101 India 1 United Kingdom 2 United States 16 Global 121

ApexBio Technology LLC

Tel: +1-832-696-8203
Fax: +1-832-641-3177
Email: info@apexbt.com
Country: United States
ProdList: 477
Advantage: 60

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38632
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

Creative Enzymes

Tel: --
Fax: --
Email: info@creative-enzymes.com
Country: United States
ProdList: 6057
Advantage: 58

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

NE Scientific

Tel: --
Fax: --
Country: United States
ProdList: 5030
Advantage: 55

LKT Laboratories, Inc.

Tel: --
Fax: --
Email: info@lktlabs.com
Country: United States
ProdList: 2164
Advantage: 64

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View Lastest Price from PFI-1 manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: PFI-1 1403764-72-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

1403764-72-6, PFI-1Related Search:

I-BET151 (GSK1210151A) (+)-JQ1 BroMosporine RVX-208 OTX015 I-BET-762

PFI-1

PFI-1 (PF-6405761)

PFI-1 (PF-06405761)

PFI 1;PFI1

CS-709

PF-06405761

Benzenesulfonamide, 2-methoxy-N-(1,2,3,4-tetrahydro-3-methyl-2-oxo-6-quinazolinyl)-

2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide PFI-1 (PF-6405761)

2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydro-quinazolin-6-yl)-bezenesulfonamide

PFI-1;PFI-1;PFI 1;PFI1

PF-6405761

PFI-1 USP/EP/BP

PFI-1cas

PFI1 PFI-1 PF-06405761 PF06405761

Inhibitor,inhibit,Apoptosis,PFI-1,Autophagy,Epigenetic Reader Domain

1403764-72-6

Inhibitors

Inhibitor