ChemicalBook > CAS DataBase List > 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one

1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one

Product Name
1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one
CAS No.
1469337-95-8
Chemical Name
1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one
Synonyms
105456;CS-1676;K-Ras G12C-IN-12;G12C INHIBITOR 12;K RAS INHIBITOR 12;K-Ras(G12C) inhibitor;K-Ras(G12C) inhibitor 12;K RAS INHIBITOR 12; G12C INHIBITOR 12;K-Ras(G12C) inhibitor 12, 10 mM in DMSO;1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)amino]acetyl]-1-piperazinyl]-2-propen-1-one
CBNumber
CB22684363
Molecular Formula
C15H17ClIN3O3
Formula Weight
449.67
MOL File
1469337-95-8.mol
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1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Property

Boiling point:
680.2±55.0 °C(Predicted)
Density 
1.736±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
≥8.98 mg/mL in DMSO with gentle warming
form 
solid
pka
8.60±0.50(Predicted)
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20118
Product name
K-Ras(G12C) Inhibitor 12
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
20118
Product name
K-Ras(G12C) Inhibitor 12
Purity
≥95%
Packaging
5mg
Price
$145
Updated
2024/03/01
Cayman Chemical
Product number
20118
Product name
K-Ras(G12C) Inhibitor 12
Purity
≥95%
Packaging
10mg
Price
$275
Updated
2024/03/01
Cayman Chemical
Product number
20118
Product name
K-Ras(G12C) Inhibitor 12
Purity
≥95%
Packaging
25mg
Price
$571
Updated
2024/03/01
ChemScene
Product number
CS-5104
Product name
K-Ras(G12C)inhibitor12
Purity
>98.0%
Packaging
50mg
Price
$900
Updated
2021/12/16
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1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Chemical Properties,Usage,Production

References

[1]. ostrem jm1, peters u, sos ml, et al. k-ras(g12c) inhibitors allosterically control gtp affinity and effector interactions. nature, 2013, 503(7477): 548-551.

1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Suppliers

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1469337-95-8, 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-oneRelated Search:

lysyllysine Everolimus K-Ras inhibitor K-Ras(G12C) inhibitor 9 K-Ras(G12C) inhibitor 6 CHIR-99021 Olaparib

  • 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one
  • 2-Propen-1-one, 1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)aMino]acetyl]-1-piperazinyl]-
  • K-Ras G12C-IN-12
  • 105456
  • CS-1676
  • G12C INHIBITOR 12
  • K RAS INHIBITOR 12
  • K RAS INHIBITOR 12; G12C INHIBITOR 12
  • K-Ras(G12C) inhibitor 12
  • 1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)amino]acetyl]-1-piperazinyl]-2-propen-1-one
  • 1-[4-[2-(4-chloro-2-hydroxy-5-iodoanilino)acetyl]piperazin-1-yl]prop-2-en-1-one k-ras(g12c)inhibitor6
  • K-Ras(G12C) inhibitor
  • 1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one USP/EP/BP
  • Apoptosis,K-Ras(G-12C) inhibitor 12,inhibit,Inhibitor,Ras,KRas(G12C) inhibitor 12,K-Ras(G12C) inhibitor 12,K Ras(G12C) inhibitor 12
  • K-Ras(G12C) inhibitor 12, 10 mM in DMSO
  • 1469337-95-8
  • C15H17ClIN3O3
  • Inhibitors