Carboxyethylgermanium sesquioxide
- Product Name
- Carboxyethylgermanium sesquioxide
- CAS No.
- 12758-40-6
- Chemical Name
- Carboxyethylgermanium sesquioxide
- Synonyms
- 99.7%;GE 132;SK-818;Serocion;REPAGERMANIUM;proxigermanium;Germanium Ge 132;ORGANIC GERMANIUM;Germanium Sesquoxide;GERMANIUM SESQUIOXIDE
- CBNumber
- CB2271237
- Molecular Formula
- C6H10Ge2O7
- Formula Weight
- 339.42
- MOL File
- 12758-40-6.mol
Carboxyethylgermanium sesquioxide Property
- Melting point:
- 320°C
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- Aqueous Base (Sparingly)
- pka
- 3.6(at 25℃)
- form
- Solid
- color
- White to Off-White
- Specific Gravity
- 1.280
- Odor
- wh. odorless powd.
- Water Solubility
- Slightly soluble in water.
- Hydrolytic Sensitivity
- 4: no reaction with water under neutral conditions
- Merck
- 14,7795
- InChIKey
- XEABSBMNTNXEJM-UHFFFAOYSA-N
- CAS DataBase Reference
- 12758-40-6(CAS DataBase Reference)
- EPA Substance Registry System
- 2-(Carboxyethyl)germanium sesquioxide (12758-40-6)
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- WGK Germany
- 2
- RTECS
- UA2459750
- TSCA
- Yes
- HS Code
- 2931.90.9051
- Toxicity
- LD50 i.p. in mice: 2.8 g/kg (Brutkiewicz)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H303May be harmfulif swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 396265
- Product name
- Bis(2-carboxyethylgermanium(IV) sesquioxide)
- Purity
- 99%
- Packaging
- 5g
- Price
- $82.4
- Updated
- 2024/03/01
- Product number
- B1367
- Product name
- Bis[2-carboxyethylgermanium(IV)] Sesquioxide
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $86
- Updated
- 2024/03/01
- Product number
- B1367
- Product name
- Bis[2-carboxyethylgermanium(IV)] Sesquioxide
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $283
- Updated
- 2024/03/01
- Product number
- 036758
- Product name
- Bis(carboxyethylgermanium) sesquioxide, 99.7%
- Packaging
- 5g
- Price
- $62.65
- Updated
- 2024/03/01
- Product number
- 036758
- Product name
- Bis(carboxyethylgermanium) sesquioxide, 99.7%
- Packaging
- 25g
- Price
- $208.65
- Updated
- 2024/03/01
Carboxyethylgermanium sesquioxide Chemical Properties,Usage,Production
Description
Propagermanium, the first organogermanium compound marketed as a pharmaceutical, is indicated for the oral treatment of chronic hepatitis B. Propagermanium is reported to enhance production of interferon α/β in virus infected mice and in human peripheral blood mononuclear cells but does not inhibit the growth of various DNA or RNA viruses in vitro. Therefore, enhancement of the host immune system against virus infection was proposed to be responsible for its antiviral activity. Propagermanium also exhibits potent antitumor activity, reportedly via stimulation of T lymphocytes to produce a lyrnphokine (s), possibly interferon-y, which induces the generation and activation of cytotoxic macrophages leading to elimination of tumor cells. Propagermanium has been reported to regulate calcium metabolism and to alleviate cancerous pain and osteocope.
Originator
Sanwa Kagaku (Japan)
Uses
A bifunctional metalloligand with metal-C (Ge-C) bonds,bis(carboxyethylgermanium) sesquioxide, has been used to make two metal-organometallic frameworks (MOMFs). bis-(carboxyethylgermanium)sesquioxide is a as a promising anti-oxidative agent. Bis(carboxyethylgermanium) sesquioxide induce INF-γ and has undergone clinical trials with promising preclinical results.
Uses
Bis(2-carboxyethylgermanium(IV) sesquioxide) can be used as a precursor in the preparation of photoluminescent carbon dots, applicable as fluorescent probes in bioimaging applications.
Uses
antifungal and antiseptic
Definition
ChEBI: Propagermanium is an organogermanium compound.
brand name
Serosion
General Description
Bis(2-carboxyethylgermanium(IV) sesquioxide), also known as repagermanium, is a water-soluble organogermanium compound that exhibits immunostimulatory properties. It is also used as an ingredient in food and cosmetics.
Safety Profile
Moderately toxic by intravenous route. Experimental reproductive effects. See also GERMANIUM COMPOUNDS.
Carboxyethylgermanium sesquioxide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Carboxyethylgermanium sesquioxide manufacturers
- Product
- Carboxyethylgermanium sesquioxide 12758-40-6
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-22
- Product
- Carboxyethylgermanium sesquioxide 12758-40-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-18
- Product
- Germanium Ge 132 12758-40-6
- Price
- US $1.70/g/Bag
- Min. Order
- 10g
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2021-07-01