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Carboxyethylgermanium sesquioxide

Product Name
Carboxyethylgermanium sesquioxide
CAS No.
12758-40-6
Chemical Name
Carboxyethylgermanium sesquioxide
Synonyms
99.7%;GE 132;SK-818;Serocion;REPAGERMANIUM;proxigermanium;Germanium Ge 132;ORGANIC GERMANIUM;Germanium Sesquoxide;GERMANIUM SESQUIOXIDE
CBNumber
CB2271237
Molecular Formula
C6H10Ge2O7
Formula Weight
339.37
MOL File
12758-40-6.mol
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Carboxyethylgermanium sesquioxide Property

Melting point:
320°C
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Aqueous Base (Sparingly)
pka
3.6(at 25℃)
form 
Solid
color 
White to Off-White
Specific Gravity
1.280
Odor
wh. odorless powd.
Water Solubility 
Slightly soluble in water.
Hydrolytic Sensitivity
4: no reaction with water under neutral conditions
Merck 
14,7795
InChIKey
XEABSBMNTNXEJM-UHFFFAOYSA-N
CAS DataBase Reference
12758-40-6(CAS DataBase Reference)
EPA Substance Registry System
2-(Carboxyethyl)germanium sesquioxide (12758-40-6)
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
2
RTECS 
UA2459750
TSCA 
Yes
HS Code 
2931.90.9051
Toxicity
LD50 i.p. in mice: 2.8 g/kg (Brutkiewicz)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
396265
Product name
Bis(2-carboxyethylgermanium(IV) sesquioxide)
Purity
99%
Packaging
5g
Price
$82.4
Updated
2024/03/01
TCI Chemical
Product number
B1367
Product name
Bis[2-carboxyethylgermanium(IV)] Sesquioxide
Purity
>98.0%(T)
Packaging
5g
Price
$86
Updated
2024/03/01
TCI Chemical
Product number
B1367
Product name
Bis[2-carboxyethylgermanium(IV)] Sesquioxide
Purity
>98.0%(T)
Packaging
25g
Price
$283
Updated
2024/03/01
Alfa Aesar
Product number
036758
Product name
Bis(carboxyethylgermanium) sesquioxide, 99.7%
Packaging
5g
Price
$62.65
Updated
2024/03/01
Alfa Aesar
Product number
036758
Product name
Bis(carboxyethylgermanium) sesquioxide, 99.7%
Packaging
25g
Price
$208.65
Updated
2024/03/01
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Carboxyethylgermanium sesquioxide Chemical Properties,Usage,Production

Description

Propagermanium, the first organogermanium compound marketed as a pharmaceutical, is indicated for the oral treatment of chronic hepatitis B. Propagermanium is reported to enhance production of interferon α/β in virus infected mice and in human peripheral blood mononuclear cells but does not inhibit the growth of various DNA or RNA viruses in vitro. Therefore, enhancement of the host immune system against virus infection was proposed to be responsible for its antiviral activity. Propagermanium also exhibits potent antitumor activity, reportedly via stimulation of T lymphocytes to produce a lyrnphokine (s), possibly interferon-y, which induces the generation and activation of cytotoxic macrophages leading to elimination of tumor cells. Propagermanium has been reported to regulate calcium metabolism and to alleviate cancerous pain and osteocope.

Originator

Sanwa Kagaku (Japan)

Uses

A bifunctional metalloligand with metal-C (Ge-C) bonds,bis(carboxyethylgermanium) sesquioxide, has been used to make two metal-organometallic frameworks (MOMFs). bis-(carboxyethylgermanium)sesquioxide is a as a promising anti-oxidative agent. Bis(carboxyethylgermanium) sesquioxide induce INF-γ and has undergone clinical trials with promising preclinical results.

Uses

Bis(2-carboxyethylgermanium(IV) sesquioxide) can be used as a precursor in the preparation of photoluminescent carbon dots, applicable as fluorescent probes in bioimaging applications.

Uses

antifungal and antiseptic

Definition

ChEBI: Propagermanium is an organogermanium compound.

brand name

Serosion

General Description

Bis(2-carboxyethylgermanium(IV) sesquioxide), also known as repagermanium, is a water-soluble organogermanium compound that exhibits immunostimulatory properties. It is also used as an ingredient in food and cosmetics.

Safety Profile

Moderately toxic by intravenous route. Experimental reproductive effects. See also GERMANIUM COMPOUNDS.

Carboxyethylgermanium sesquioxide Preparation Products And Raw materials

Raw materials

Preparation Products

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Carboxyethylgermanium sesquioxide Suppliers

Intatrade Chemicals Gmbh
Tel
--
Fax
--
Email
intatrade@intatrade.de
Country
Germany
ProdList
307
Advantage
58
Alfa Aesar, Thermo Fisher Scientific
Tel
--
Fax
--
Email
es@alfa.com
Country
Germany
ProdList
5123
Advantage
58
ChemPur GmbH
Tel
--
Fax
--
Email
info@ChemPur.de
Country
Germany
ProdList
2737
Advantage
50
CHEMOS GmbH & Co. KG
Tel
--
Fax
--
Email
chemos@chemos.de
Country
Germany
ProdList
6727
Advantage
58
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from Carboxyethylgermanium sesquioxide manufacturers

Hebei Chuanghai Biotechnology Co,.LTD
Product
Germanium Ge 132 12758-40-6
Price
US $1.70/KG
Min. Order
10KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-21
Hebei Weibang Biotechnology Co., Ltd
Product
Carboxyethylgermanium sesquioxide 12758-40-6
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2021-08-25
Henan Fengda Chemical Co., Ltd
Product
Carboxyethylgermanium sesquioxide 12758-40-6
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-22

12758-40-6, Carboxyethylgermanium sesquioxideRelated Search:


  • ORGANIC GERMANIUM
  • CARBOXYETHYLGERMANIUM SESQUIOXIDE
  • BIS(CARBOXYETHYLGERMANIUM SESQUIOXIDE)
  • BIS-BETA CARBOXYETHYLGERMANIUM SESQUIOXIDE
  • BETA-CARBOXYETHYLGERMANIUM OXIDE
  • BETA-CARBOXYETHYLGERMANIUM SESQUIOXIDE
  • BIS[2-CARBOXYETHYLGERMANIUM(IV)] SESQUIOXIDE
  • BIS(2-CARBOXYETHYLGERMANIUM SESQUIOXIDE)
  • GERMANIUM SESQUIOXIDE
  • GE 132
  • 3,3'-(1,3-DIOXO-1,3-DIGERMOXANEDIYL)BISPROPIONIC ACID
  • 3,3-(1,3-dioxo-1,3-digermoxanediyl)-bispropionic
  • REPAGERMANIUM
  • 99.7%
  • GERMANIUMSESQUIOXIDE,POWDER
  • proxigermanium
  • 1-PHENYL-2-CARBOXYLETHYLGERMANIUMSESQUISULPHIDE
  • Bis(carboxyethylgermanium) sesquioxide, 99.7%
  • 2-Carboxyethylgermanium sesquioxide
  • 3,3'-(1,3-Dioxo-1,3-digermoxanediyl)dipropionic acid
  • Germanium Sesquoxide
  • Propanoic acid, 3,3'-(1,3-dioxo-1,3-digermoxanediyl)bis
  • Serocion
  • 3-Oxygermylpropionic acid polymer
  • SK-818
  • 3,3'-(1,3-Dioxo-1,3-digerma-2-oxapropane-1,3-diyl)bispropionic acid
  • 3,3'-(1,3-Dioxodigermoxane-1,3-diyl)dipropionic acid
  • GerManiuM Sesquioxide USP
  • Bis(2-carboxyethylgermanium(IV) sesquioxide), 99.5%
  • organogermanium compound
  • Bis[2-carboxyethylgermanium(IV)] Sesquioxide &gt
  • Carboxyethylgermanium sesquioxide ISO 9001:2015 REACH
  • Germanium Ge 132
  • Bis(2-carboxyethylgermanium(IV) sesquioxide),99.95%
  • Dipropanoic acid germanium sequioxide
  • 12758-40-6
  • OGeOCH2CH2CO2H2
  • C6H10O7Ge2
  • C6H10GeO7
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Ge (Germanium) Compounds
  • Semimetal Compounds
  • Classes of Metal Compounds
  • Organometallic Reagents
  • Others
  • Organogermanium
  • Immune Cell Signaling and Blood
  • Immune System Regulation
  • Immunomodulators and Antibiotics
  • Nutritional Supplements
  • Ge (Germanium) Compounds
  • Classes of Metal Compounds
  • Semimetal Compounds