Isojacareubin
- Product Name
- Isojacareubin
- CAS No.
- 50597-93-8
- Chemical Name
- Isojacareubin
- Synonyms
- Isojacareubin;6,10,11-Trihydroxy-3,3-dimethylpyrano[2,3-c]xanthen-7(3H)-one;3H,7H-Pyrano[2,3-c]xanthen-7-one, 6,10,11-trihydroxy-3,3-dimethyl-
- CBNumber
- CB22725422
- Molecular Formula
- C18H14O6
- Formula Weight
- 326.3
- MOL File
- 50597-93-8.mol
Isojacareubin Property
- form
- Solid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- AS116737
- Product name
- Isojacareubin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $348
- Updated
- 2021/12/16
- Product number
- CSN14537
- Product name
- Isojacareubin
- Packaging
- 1mg
- Price
- $351
- Updated
- 2021/12/16
- Product number
- CD32001208
- Product name
- Isojacareubin
- Purity
- 95+%
- Packaging
- 5mg
- Price
- $723
- Updated
- 2021/12/16
- Product number
- CSN14537
- Product name
- Isojacareubin
- Packaging
- 5mg
- Price
- $877
- Updated
- 2021/12/16
Isojacareubin Chemical Properties,Usage,Production
Uses
Isojacareubin can be isolated from Hypericum japonicum. Isojacareubin covalently inhibits SARS-CoV-2 3CLpro. Isojacareubin also has anti-helicobacter activity. Isojacareubin inhibits PKC, and suppresses hepatocellular carcinoma metastasis and induces apoptosis[1][2][3].
References
[1] Kyoko Ishiguro, et al. An isopentenylated flavonol from Hypericum japonicum. Phytochemistry. 1993. 32 (6), 1583-1585.
[2] Khan A, et al. Discovery of Isojacareubin as a covalent inhibitor of SARS-CoV-2 main protease using structural and experimental approaches. J Med Virol. 2023 Feb;95(2):e28542. DOI:10.1002/jmv.28542
[3] Yuan X, et al. Inhibition of protein kinase C by isojacareubin suppresses hepatocellular carcinoma metastasis and induces apoptosis in vitro and in vivo. Sci Rep. 2015 Aug 6;5:12889. DOI:10.1038/srep12889
Isojacareubin Preparation Products And Raw materials
Raw materials
Preparation Products
Isojacareubin Suppliers
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View Lastest Price from Isojacareubin manufacturers
- Product
- Isojacareubin 50597-93-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 5mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-06