2-Amino-3-pyridinecarboxaldehyde
- Product Name
- 2-Amino-3-pyridinecarboxaldehyde
- CAS No.
- 7521-41-7
- Chemical Name
- 2-Amino-3-pyridinecarboxaldehyde
- Synonyms
- 2-AMINONICOTINALDEHYDE;3-PYRIDINECARBOXALDEHYDE, 2-AMINO-;3-formylpyridin-2-amine;2-AMINO-3-FORMYLPYRIDINE;2-aminonicotinaldehyde 1;2-Aminonicotinaldehyde 99%;2-Aminonicotinaldehyde >2-Aminopyridine-3-carboxaL;2-AMINO-PYRIDIN-3-CARBALDEHYDE;2-Amino-3-pyridinecarbaldehyde
- CBNumber
- CB2272966
- Molecular Formula
- C6H6N2O
- Formula Weight
- 122.12
- MOL File
- 7521-41-7.mol
2-Amino-3-pyridinecarboxaldehyde Property
- Melting point:
- 98-102 °C (lit.)
- Boiling point:
- 290.7±25.0 °C(Predicted)
- Density
- 1.264±0.06 g/cm3(Predicted)
- Flash point:
- >300℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Soluble in Ether, Ethyl acetate, Chloroform (Slightly), Methanol (Slightly)
- pka
- 4.99±0.36(Predicted)
- form
- Powder, Crystals and/or Chunks
- color
- Yellow to light brown
- Water Solubility
- insoluble
- Sensitive
- Air Sensitive
- BRN
- 109598
- InChIKey
- NXMFJCRMSDRXLD-UHFFFAOYSA-N
- CAS DataBase Reference
- 7521-41-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36-36/37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- PackingGroup
- II
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 639109
- Product name
- 2-Amino-3-pyridinecarboxaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $97.6
- Updated
- 2023/06/20
- Product number
- 639109
- Product name
- 2-Amino-3-pyridinecarboxaldehyde
- Purity
- 97%
- Packaging
- 5g
- Price
- $438
- Updated
- 2023/06/20
- Product number
- A1818
- Product name
- 2-Aminonicotinaldehyde
- Purity
- >97.0%(GC)
- Packaging
- 1g
- Price
- $52
- Updated
- 2024/03/01
- Product number
- A1818
- Product name
- 2-Aminonicotinaldehyde
- Purity
- >97.0%(GC)
- Packaging
- 5g
- Price
- $154
- Updated
- 2024/03/01
- Product number
- L19620
- Product name
- 2-Aminopyridine-3-carboxaldehyde, 98%
- Packaging
- 1g
- Price
- $45.65
- Updated
- 2024/03/01
2-Amino-3-pyridinecarboxaldehyde Chemical Properties,Usage,Production
Chemical Properties
yellow crystals
Uses
2-Aminonicotinaldehyde is commonly employed as a starting material for a wide variety of N-heterocyclic compounds (e.g. β-nicotyrine [N445000]) . 2-Aminonicotinaldehyde is also used as a reagent to synthesize hydrazones (e.g.thionaphthenquinone 3-hydrazone [T367720]), which possess antituburcular properties.
Preparation
Preparative Methods of 2-Amino-3-pyridinecarboxaldehyde: the reagent is best when freshly prepared. A multistep procedure starting from 2-amino-3-
picoline has been improved upon by a simple two-step approach. Sulfamation of nicotinamide with ammonium
sulfamate (both commercially available) provides 2-(3′-pyridyl)pyrido[2,3-d]pyridimine which may be
hydrolyzed in 2 N HCl to provide the reagent (eq 1)[1]. Substituted derivatives of the reagent may be prepared via
a similar intermediate.
storage
2-Amino-3-pyridinecarboxaldehyde is somewhat more stable than 2-Aminobenzaldehyde and may be stored for up to several months at 0 °C under an inert atmosphere. Sublimation is a convenient method for the separation of higher oligomers which may accumulate during storage. Use in a fume hood.
References
1. (a) Caluwe, P. T 1980, 36, 2359. (b) Cheng, C.-C.; Yan, S.-J. OR 1982, 28, 37. (c) Thummel, R. P. SL 1992, 1.
2-Amino-3-pyridinecarboxaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-3-pyridinecarboxaldehyde manufacturers
- Product
- 2-Amino-3-pyridinecarboxaldehyde 7521-41-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-31
- Product
- 2-Amino-3-pyridinecarboxaldehyde 7521-41-7
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-29
- Product
- 2-Amino-3-pyridinecarboxaldehyde 7521-41-7
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2024-08-15