FLLL31

ChemicalBook > CAS DataBase List > FLLL31

Product Name: FLLL31
CAS No.: 52328-97-9
Chemical Name: FLLL31
Synonyms: FLLL31;FLLL31 >=98% (HPLC);Tetramethylcurcumin;FLLL31;FLLL-31;FLLL 31;(E,E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethyl-1,6-heptadiene-3,5-dione;(1E,6E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethyl-1,6-heptadiene-3,5-dione;(1E,6E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethylhepta-1,6-diene-3,5-dione;1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4,4-dimethyl-, (1E,6E)-;pancreatic,FLLL-31,domain,FLLL 31,Apoptosis,Inhibitor,STAT,Tetramethylcurcumin,cancer,kinase,Curcumin,Janus,Src,anti-inflammatory,FLLL31,breast,inhibit,homology-2
CBNumber: CB22731058
Molecular Formula: C25H28O6
Formula Weight: 424.49
MOL File: 52328-97-9.mol

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FLLL31 Property

Boiling point:: 594.5±50.0 °C(Predicted)
Density: 1.140±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: ≥10mg/mL
form: powder
color: yellow

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: F9057
Product name: FLLL31
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $134
Updated: 2024/03/01

Sigma-Aldrich

Product number: F9057
Product name: FLLL31
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $436
Updated: 2024/03/01

Usbiological

Product number: 301048
Product name: Tetramethylcurcumin
Packaging: 20mg
Price: $665
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb259527
Product name: Tetramethylcurcumin
Purity: 98%
Packaging: 20mg
Price: $596.7
Updated: 2021/12/16

ChemScene

Product number: CS-0022792
Product name: Tetramethylcurcumin
Packaging: 5mg
Price: $235
Updated: 2021/12/16

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FLLL31 Chemical Properties,Usage,Production

Biological Activity

Tetramethylcurcumin (FLLL31) is derived from curcumin and specifically inhibits phosphorylation of STAT3 by selectively binding to Janus kinase 2 and the STAT3 Src homology 2 domain. Tetramethylcurcumin has anti-inflammatory and anticancer effects.

in vitro

Tetramethylcurcumin (FLLL31; 2.5 and 5 μM; for 24 hours) downregulas STAT3 phosphorylation and DNA-binding activity in MDA-MB-231 breast and PANC-1 pancreatic cancer cells.
Tetramethylcurcumin inhibits cell viability , cell invasion. Tetramethylcurcumin is an effective inhibitor of STAT3 phosphorylation, DNA-binding activity, and transactivation in vitro, leading to the impediment of multiple oncogenic processes and the induction of apoptosis in pancreatic and breast cancer cell lines.

target

STAT3

FLLL31 Preparation Products And Raw materials

Raw materials

Preparation Products

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FLLL31 Suppliers

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52328-97-9, FLLL31Related Search:

2,2-DIMETHYLTETRAHYDROFURAN Curcumin (3S,5S)-1,7-BIS(4-HYDROXY-3-METHOXYPHENYL)HEPTANE-3,5-DIOL DihydrocurcuMin 5"-MethoxyhexahydrocurcuMin BIS(4-HYDROXYCINNAMOYL)METHANE Tetrahydrocurcumin HEXAHYDROCURCUMIN DEMETHOXYCURCUMIN ASC-J9

FLLL31

Tetramethylcurcumin

(E,E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethyl-1,6-heptadiene-3,5-dione

(1E,6E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethyl-1,6-heptadiene-3,5-dione

FLLL31;FLLL-31;FLLL 31

1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4,4-dimethyl-, (1E,6E)-

FLLL31 >=98% (HPLC)

(1E,6E)-1,7-Bis(3,4-dimethoxyphenyl)-4,4-dimethylhepta-1,6-diene-3,5-dione

pancreatic,FLLL-31,domain,FLLL 31,Apoptosis,Inhibitor,STAT,Tetramethylcurcumin,cancer,kinase,Curcumin,Janus,Src,anti-inflammatory,FLLL31,breast,inhibit,homology-2

52328-97-9