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Nintedanib

Product Name
Nintedanib
CAS No.
1174335-83-1
Chemical Name
Nintedanib
Synonyms
Methyl (E)-1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;(3E)-1-(2-Chloroacetyl)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester;Nintedanib impurities2;Nintedanib Impurity 148;Intedanib(Nintedanib) Impurity 17;Nintedanib Impurity 2 (Intedanib Impurity 2);(E)-1-cholroacetyl-3-(methoxy(phenyl)methylene)-2-indolone-6-methylformate;methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;methyl-1 -(chloroacetyl)-3- [methoxy(phenyl)methylene]-2-oxoindoline-6-carboxylate;(E)-methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
CBNumber
CB22741480
Molecular Formula
C20H16ClNO5
Formula Weight
385.8
MOL File
1174335-83-1.mol
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Nintedanib Property

Boiling point:
571.9±50.0 °C(Predicted)
Density 
1.374±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
pka
-2.57±0.20(Predicted)
Appearance
Light yellow to yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-M3032
Product name
1H-Indole-6-carboxylicacid,1-(2-chloroacetyl)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-,methylester,(3E)-
Packaging
100mg
Price
$258
Updated
2021/12/16

Nintedanib Preparation Products And Raw materials

Raw materials

Preparation Products

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Nintedanib Suppliers

China 43 India 2 United Kingdom 1 United States 1 Global 47
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Quality Control Solutions Ltd.
Tel
0755-66853366 13670046396
Fax
0755-28363542
Email
orders@qcsrm.com
Country
China
ProdList
18422
Advantage
56
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
4876
Advantage
55
Changzhou Fang Nan Medical Technology Co., Ltd.
Tel
0519-85283268
Country
China
ProdList
116
Advantage
55
ShangHai Movin Pharmaceutical Co., Ltd.
Tel
13681854265
Email
info@moenpharm.com
Country
China
ProdList
484
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shanghai Brain Biotechnology Co., Ltd.
Tel
13564638271
Email
shhjiang1977@163.com
Country
China
ProdList
2989
Advantage
55
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10029
Advantage
58
Hubei widely chemical technology Co., Ltd.
Tel
027-83991130 18627774460
Fax
027-83991130
Email
1718093273@QQ.COM
Country
China
ProdList
1647
Advantage
58
Heta Pharm & Chem CO.,Ltd.
Tel
+86-571-88298691 89905385
Fax
+86-571-87353175
Email
sales@hetapharm.com
Country
China
ProdList
72
Advantage
60

1174335-83-1, NintedanibRelated Search:

N-(4-aMinophenyl)-2-chloro-N-MethylacetaMide Nintedanib Ethanesulfonic acid ethyl ester BIBF 1202 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID ETHYL ESTER Nintedanib Impurity 17 (Intedanib Impurity 17) Nintedanib Impurity 5 (Intedanib Impurity 5) Nintedanib Impurity 3 (Intedanib Impurity 3) (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Nintedanib Impurity E (Intedanib Impurity E) Nintedanib Impurity 24 Nintedanib Impurity 16 Nintedanib Impurity G (Intedanib Impurity G) Methyl ethanesulfonate (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Nintedanib Impurity 15 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate (3E)-1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylic Acid Methyl Ester

  • methyl-1 -(chloroacetyl)-3- [methoxy(phenyl)methylene]-2-oxoindoline-6-carboxylate
  • 1H-Indole-6-carboxylic acid, 1-(2-chloroacetyl)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-, methyl ester, (3E)-
  • (3E)-1-(2-Chloroacetyl)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester
  • methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
  • 1-(2-chloroacetyl)-3-[1-methoxy-1-phenylmeth-(E)-ylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
  • Nintedanib Impurity 2 (Intedanib Impurity 2)
  • (E)-methyl 1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
  • Methyl (E)-1-(2-chloroacetyl)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
  • (E)-1-cholroacetyl-3-(methoxy(phenyl)methylene)-2-indolone-6-methylformate
  • Nintedanib impurities2
  • Intedanib(Nintedanib) Impurity 17
  • Methyl (3E)-1-(2-chloroacetyl)-2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylate
  • Nintedanib Impurity 148
  • 1174335-83-1