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BIBF 1202

Product Name
BIBF 1202
CAS No.
894783-71-2
Chemical Name
BIBF 1202
Synonyms
CS-1313;BIBF 1202;Nintedanib-1;Nintedanib-010;Intedanib Impurity A;Nintedanib impurity A;Nintedanib impuritiesA;Nintedanib Impurity N1;Nintedanib impurities26;Nintedanib Carboxylic Acid
CBNumber
CB22705077
Molecular Formula
C30H31N5O4
Formula Weight
525.6
MOL File
894783-71-2.mol
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BIBF 1202 Property

Melting point:
>216°C (dec.)
Boiling point:
759.5±60.0 °C(Predicted)
Density 
1.331±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Aqueous Base (Slightly, Heated)
pka
3.94±0.20(Predicted)
form 
Solid
color 
Light Yellow to Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27176
Product name
BIBF 1202
Packaging
1mg
Price
$40
Updated
2024/03/01
Cayman Chemical
Product number
27176
Product name
BIBF 1202
Packaging
10mg
Price
$197
Updated
2024/03/01
Cayman Chemical
Product number
27176
Product name
BIBF 1202
Packaging
5mg
Price
$139
Updated
2024/03/01
TRC
Product number
N478285
Product name
NintedanibCarboxylicAcid
Packaging
50mg
Price
$750
Updated
2021/12/16
ChemScene
Product number
CS-3025
Product name
BIBF1202
Purity
99.29%
Packaging
5mg
Price
$900
Updated
2021/12/16
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BIBF 1202 Chemical Properties,Usage,Production

Description

BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.

Uses

Nintedanib Carboxylic Acid is a related compound of Intedanib (I666650), an indolinone derivative that inhibits angiokinase and an antitumor agent.

BIBF 1202 Preparation Products And Raw materials

Raw materials

Preparation Products

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BIBF 1202 Suppliers

China 87 India 3 United Kingdom 1 United States 9 Global 100
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Beijing Comparison Pharmaceutical Technology Co., Ltd
Tel
010-52878169 15701683040
Email
sales@bjcomparison.com
Country
China
ProdList
4678
Advantage
58
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7553
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17982
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9911
Advantage
50
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4121
Advantage
55
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-58362220 15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7715
Advantage
55
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9254
Advantage
55

894783-71-2, BIBF 1202Related Search:

Nintedanib N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID ETHYL ESTER (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 1-Chloro-4-(trimethoxymethyl)benzene Methyl 4-chloro-3-nitrobenzoate 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE 4'-Amino-N-methylacetanilide Ethanesulfonic acid ethyl ester (3E)-1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylic Acid Methyl Ester N-(4-aMinophenyl)-2-chloro-N-MethylacetaMide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Methyl 1-acetyl-2-oxoindoline-6-carboxylate Nintedanib Impurity 15 P-ANISALDEHYDE DIMETHYL ACETAL Methyl oxindole-5-carboxylate

  • (Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid
  • Nintedanib impurity A
  • Intedanib Impurity A
  • Nintedanib Carboxylic Acid
  • Nintedanib-010
  • BIBF 1202
  • (3Z)-2,3-Dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid
  • Nintedanib-1
  • CS-1313
  • Nintedanib impurity 9/Nintedanib Carboxylic Acid/(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl) methylene)-2-oxoindoline-6-carboxylic acid
  • 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, (3Z)-
  • Nintedanib impurities26
  • Nintedanib impuritiesA
  • Nintedanib Impurity 6Q: What is Nintedanib Impurity 6 Q: What is the CAS Number of Nintedanib Impurity 6 Q: What is the storage condition of Nintedanib Impurity 6 Q: What are the applications of Nintedanib Impurity 6
  • NintedanibImpurity6-13C-d3
  • (3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenyl-methylene]-2-oxo-indoline-6-carboxylic acid
  • Nintedanib Impurity N1
  • 894783-71-2
  • C30H31N5O4