Methyl 1-acetyl-2-oxoindoline-6-carboxylate

Product Name: Methyl 1-acetyl-2-oxoindoline-6-carboxylate
CAS No.: 676326-36-6
Chemical Name: Methyl 1-acetyl-2-oxoindoline-6-carboxylate
Synonyms: Nintedanib-002;methyl-1-acetyl2-oxoindole-6-carboxylate;Methyl 1-acetyl-2-oxoindoline-6-carboxylate;methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate;Methyl 1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylate;Methyl 1-acetyI-2-oxo-2,3-dihydro-1H-indoIe-6-carboxyIate;TIANFU-CHEM - Methyl 1-acetyl-2-oxoindoline-6-carboxylate;1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methy...;Nintedanib impurity 1/Methyl 1-Acetyl-2-oxoindoline-6-carboxylate;1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
CBNumber: CB82520764
Molecular Formula: C12H11NO4
Formula Weight: 233.22
MOL File: 676326-36-6.mol

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Methyl 1-acetyl-2-oxoindoline-6-carboxylate Property

Boiling point:: 489.5±45.0 °C(Predicted)
Density: 1.330
solubility: DMSO (Slightly), Methanol (Slightly)
pka: -1.94±0.20(Predicted)
form: Solid
color: Off-White to Pale Red

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M330593
Product name: Methyl1-Acetyl-2-oxoindoline-6-carboxylate
Packaging: 1g
Price: $545
Updated: 2021/12/16

Matrix Scientific

Product number: 131561
Product name: Methyl1-acetyl-2-oxoindoline-6-carboxylate
Purity: 97%
Packaging: 5g
Price: $1432
Updated: 2021/12/16

Matrix Scientific

Product number: 131561
Product name: Methyl1-acetyl-2-oxoindoline-6-carboxylate
Purity: 97%
Packaging: 10g
Price: $2160
Updated: 2021/12/16

ChemScene

Product number: CS-M2961
Product name: methyl1-acetyl-2-oxoindoline-6-carboxylate
Packaging: 1g
Price: $150
Updated: 2021/12/16

ChemScene

Product number: CS-M2961
Product name: methyl1-acetyl-2-oxoindoline-6-carboxylate
Packaging: 5g
Price: $500
Updated: 2021/12/16

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Methyl 1-acetyl-2-oxoindoline-6-carboxylate Chemical Properties,Usage,Production

Uses

Methyl 1-Acetyl-2-oxoindoline-6-carboxylate is a reagent used in the preparation of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

Methyl 1-acetyl-2-oxoindoline-6-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 1-acetyl-2-oxoindoline-6-carboxylate Suppliers

China 78 India 4 United Kingdom 1 United States 7 Global 90

Shanghai Boyle Chemical Co., Ltd.

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SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.

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View Lastest Price from Methyl 1-acetyl-2-oxoindoline-6-carboxylate manufacturers

Career Henan Chemical Co

Product: Methyl 1-acetyl-2-oxoindoline-6-carboxylate 676326-36-6
Price: US $1.80-3.60/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 88kg
Release date: 2019-07-31

676326-36-6, Methyl 1-acetyl-2-oxoindoline-6-carboxylateRelated Search:

BIBF 1202 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID ETHYL ESTER N-(4-aMinophenyl)-2-chloro-N-MethylacetaMide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester 1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester METHYL OXINDOLE-7-CARBOXYLATE 1-Chloro-4-(trimethoxymethyl)benzene N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide P-ANISALDEHYDE DIMETHYL ACETAL Methyl oxindole-5-carboxylate N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Nintedanib Methyl 4-chloro-3-nitrobenzoate 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE

Methyl 1-acetyl-2-oxoindoline-6-carboxylate

1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methyl ester

Nintedanib-002

1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester

methyl-1-acetyl2-oxoindole-6-carboxylate

Nintedanib impurity 1/Methyl 1-Acetyl-2-oxoindoline-6-carboxylate

1H-Indole-6-carboxylic acid, 1-acetyl-2,3-dihydro-2-oxo-, methyl ester

methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate

Methyl 1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylate

1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methy...

TIANFU-CHEM - Methyl 1-acetyl-2-oxoindoline-6-carboxylate

Methyl 1-acetyI-2-oxo-2,3-dihydro-1H-indoIe-6-carboxyIate

Methyl 1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylate(Nintedanib N-acyl oxindole)

676326-36-6