ChemicalBook > CAS DataBase List > Methyl 1-acetyl-2-oxoindoline-6-carboxylate

Methyl 1-acetyl-2-oxoindoline-6-carboxylate

Product Name
Methyl 1-acetyl-2-oxoindoline-6-carboxylate
CAS No.
676326-36-6
Chemical Name
Methyl 1-acetyl-2-oxoindoline-6-carboxylate
Synonyms
Nintedanib-002;methyl-1-acetyl2-oxoindole-6-carboxylate;Methyl 1-acetyl-2-oxoindoline-6-carboxylate;methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate;Methyl 1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylate;Methyl 1-acetyI-2-oxo-2,3-dihydro-1H-indoIe-6-carboxyIate;TIANFU-CHEM - Methyl 1-acetyl-2-oxoindoline-6-carboxylate;1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methy...;Nintedanib impurity 1/Methyl 1-Acetyl-2-oxoindoline-6-carboxylate;1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
CBNumber
CB82520764
Molecular Formula
C12H11NO4
Formula Weight
233.22
MOL File
676326-36-6.mol
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Methyl 1-acetyl-2-oxoindoline-6-carboxylate Property

Boiling point:
489.5±45.0 °C(Predicted)
Density 
1.330
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
-1.94±0.20(Predicted)
form 
Solid
color 
Off-White to Pale Red
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M330593
Product name
Methyl1-Acetyl-2-oxoindoline-6-carboxylate
Packaging
1g
Price
$545
Updated
2021/12/16
Matrix Scientific
Product number
131561
Product name
Methyl1-acetyl-2-oxoindoline-6-carboxylate
Purity
97%
Packaging
5g
Price
$1432
Updated
2021/12/16
Matrix Scientific
Product number
131561
Product name
Methyl1-acetyl-2-oxoindoline-6-carboxylate
Purity
97%
Packaging
10g
Price
$2160
Updated
2021/12/16
ChemScene
Product number
CS-M2961
Product name
methyl1-acetyl-2-oxoindoline-6-carboxylate
Packaging
1g
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-M2961
Product name
methyl1-acetyl-2-oxoindoline-6-carboxylate
Packaging
5g
Price
$500
Updated
2021/12/16
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Methyl 1-acetyl-2-oxoindoline-6-carboxylate Chemical Properties,Usage,Production

Uses

Methyl 1-Acetyl-2-oxoindoline-6-carboxylate is a reagent used in the preparation of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.

Methyl 1-acetyl-2-oxoindoline-6-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methyl 1-acetyl-2-oxoindoline-6-carboxylate manufacturers

Career Henan Chemical Co
Product
Methyl 1-acetyl-2-oxoindoline-6-carboxylate 676326-36-6
Price
US $1.80-3.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
88kg
Release date
2019-07-31

676326-36-6, Methyl 1-acetyl-2-oxoindoline-6-carboxylateRelated Search:

BIBF 1202 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID ETHYL ESTER N-(4-aMinophenyl)-2-chloro-N-MethylacetaMide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester 1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester METHYL OXINDOLE-7-CARBOXYLATE 1-Chloro-4-(trimethoxymethyl)benzene N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide P-ANISALDEHYDE DIMETHYL ACETAL Methyl oxindole-5-carboxylate N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide Nintedanib Methyl 4-chloro-3-nitrobenzoate 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE

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  • 1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
  • methyl-1-acetyl2-oxoindole-6-carboxylate
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  • 1H-Indole-6-carboxylic acid, 1-acetyl-2,3-dihydro-2-oxo-, methyl ester
  • methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate
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  • 1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methy...
  • TIANFU-CHEM - Methyl 1-acetyl-2-oxoindoline-6-carboxylate
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  • Methyl 1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylate(Nintedanib N-acyl oxindole)
  • 676326-36-6