(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester

Product Name: (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester
CAS No.: 1168150-46-6
Chemical Name: (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester
Synonyms: (3E)-2;Nintedanib-017;BIBF1120 Intermediate4;Nintedanib impurities3;Nintedanib Impurity 125;Nintedanib Intermediate 4;Nintedanib ethanesulfonate intermediates;oxo-1h-indole-6-carboxylic acid methyl ester;3E-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-...;methyl (E)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
CBNumber: CB92671010
Molecular Formula: C18H15NO4
Formula Weight: 309.32
MOL File: 1168150-46-6.mol

More

Less

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Property

Boiling point:: 523.8±50.0 °C(Predicted)
Density: 1.273±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 10.62±0.20(Predicted)
form: Solid
color: Light Yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: M322025
Product name: (E)-Methyl3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Packaging: 100mg
Price: $110
Updated: 2021/12/16

TRC

Product number: M322025
Product name: (E)-Methyl3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Packaging: 250mg
Price: $225
Updated: 2021/12/16

TRC

Product number: M322025
Product name: (E)-Methyl3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Packaging: 500mg
Price: $425
Updated: 2021/12/16

TRC

Product number: M322025
Product name: (E)-Methyl3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Packaging: 1g
Price: $795
Updated: 2021/12/16

AK Scientific

Product number: 0001AP
Product name: Methyl(3E)-3-[methoxy(phenyl)methylene]-2-oxo-6-indolinecarboxylate
Packaging: 25mg
Price: $39
Updated: 2021/12/16

More

Less

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Chemical Properties,Usage,Production

Uses

(E)-Methyl 3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is an intermediate of (E)-Intedanib [I666670]. It is also used as a reactant in the preparation of deuterated derivatives of Nintedanib (N478290), which is angiokinase inhibitor with antitumor activity.

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Suppliers

China 128 India 6 United Kingdom 1 United States 4 Global 139

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 4996
Advantage: 50

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9442
Advantage: 58

SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.

Tel: 021-34666753 13311639313
Fax: +86-21-34979012
Email: info@shyrchem.com
Country: China
ProdList: 570
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41132
Advantage: 60

Chengdu Climb Pharmaceutical Technology Co., Ltd.

Tel: 028-87608726 13540107218
Fax: 028-87608725
Email: sales@cdclimb.com
Country: China
ProdList: 104
Advantage: 58

Jinan XuanDe Chemical Co., Ltd.

Tel: 0531-88803958; 18866891188
Fax: 0531-82777287
Email: zhaojiangxia@shiningpharm.com
Country: China
ProdList: 264
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Shanghai SE Pharm Co., Ltd

Tel: 18112588827
Email: sales4@sepharm.com.cn
Country: China
ProdList: 306
Advantage: 60

Lihe Wuhan New Chemical Materials Co., Ltd.

Tel: 027-88395709
Fax: 027-88391805
Country: China
ProdList: 430
Advantage: 50

More

Less

View Lastest Price from (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester manufacturers

Nanjing Fred Technology Co., Ltd

Product: (E)-methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 1168150-46-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2023-12-19

Henan Aochuang Chemical Co.,Ltd.

Product: (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester 1168150-46-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-30

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: methyl (E)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 1168150-46-6
Price: US $100.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 98%
Supply Ability: 10KG
Release date: 2021-09-13

1168150-46-6, (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl esterRelated Search:

Methyl 2-oxoindole-6-carboxylate 1-Chloro-4-(trimethoxymethyl)benzene Methyl 1-acetyl-2-oxoindoline-6-carboxylate N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide BIBF 1202 (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Avibactam sodium Nintedanib 1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester Avibactam INT 1 BIBF-1120 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE Nintedanib Ethanesulfonate Salt 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide 2-broMo-N-Methyl-N-(4-nitrophenyl)acetaMide

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester

BIBF1120 Intermediate4

Nintedanib ethanesulfonate intermediates

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl este

methyl (E)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-, methyl ester, (3E)-

Nintedanib Intermediate 4

(3E)-2

3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester

Nintedanib-017

oxo-1h-indole-6-carboxylic acid methyl ester

Nintedanib Impurity 125

3E-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-...

Nintedanib impurities3

1168150-46-6