BIBF 1202

ChemicalBook > CAS DataBase List > BIBF 1202

Product Name: BIBF 1202
CAS No.: 894783-71-2
Chemical Name: BIBF 1202
Synonyms: CS-1313;BIBF 1202;Nintedanib-1;Nintedanib-010;Intedanib Impurity A;Nintedanib impurity A;Nintedanib impuritiesA;Nintedanib Impurity N1;Nintedanib impurities26;Nintedanib Carboxylic Acid
CBNumber: CB22705077
Molecular Formula: C30H31N5O4
Formula Weight: 525.6
MOL File: 894783-71-2.mol

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BIBF 1202 Property

Melting point:: >216°C (dec.)
Boiling point:: 759.5±60.0 °C(Predicted)
Density: 1.331±0.06 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Aqueous Base (Slightly, Heated)
pka: 3.94±0.20(Predicted)
form: Solid
color: Light Yellow to Yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27176
Product name: BIBF 1202
Packaging: 1mg
Price: $40
Updated: 2024/03/01

Cayman Chemical

Product number: 27176
Product name: BIBF 1202
Packaging: 10mg
Price: $197
Updated: 2024/03/01

Cayman Chemical

Product number: 27176
Product name: BIBF 1202
Packaging: 5mg
Price: $139
Updated: 2024/03/01

TRC

Product number: N478285
Product name: NintedanibCarboxylicAcid
Packaging: 50mg
Price: $750
Updated: 2021/12/16

ChemScene

Product number: CS-3025
Product name: BIBF1202
Purity: 99.29%
Packaging: 1mg
Price: $228
Updated: 2021/12/16

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BIBF 1202 Chemical Properties,Usage,Production

Description

BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC₅₀ value of 62 nM.

Uses

Nintedanib Carboxylic Acid is a related compound of Intedanib (I666650), an indolinone derivative that inhibits angiokinase and an antitumor agent.

BIBF 1202 Preparation Products And Raw materials

Raw materials

Preparation Products

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894783-71-2, BIBF 1202Related Search:

Nintedanib N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID ETHYL ESTER (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 1-Chloro-4-(trimethoxymethyl)benzene Methyl 4-chloro-3-nitrobenzoate 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE 4'-Amino-N-methylacetanilide Ethanesulfonic acid ethyl ester (3E)-1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylic Acid Methyl Ester N-(4-aMinophenyl)-2-chloro-N-MethylacetaMide 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Methyl 1-acetyl-2-oxoindoline-6-carboxylate Nintedanib Impurity 15 P-ANISALDEHYDE DIMETHYL ACETAL Methyl oxindole-5-carboxylate

(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid

Nintedanib impurity A

Intedanib Impurity A

Nintedanib Carboxylic Acid

Nintedanib-010

BIBF 1202

(3Z)-2,3-Dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid

Nintedanib-1

CS-1313

Nintedanib impurity 9/Nintedanib Carboxylic Acid/(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl) methylene)-2-oxoindoline-6-carboxylic acid

1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, (3Z)-

Nintedanib impurities26

Nintedanib impuritiesA

Nintedanib Impurity 6Q: What is Nintedanib Impurity 6 Q: What is the CAS Number of Nintedanib Impurity 6 Q: What is the storage condition of Nintedanib Impurity 6 Q: What are the applications of Nintedanib Impurity 6

NintedanibImpurity6-13C-d3

(3Z)-3-[[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]anilino]-phenyl-methylene]-2-oxo-indoline-6-carboxylic acid

Vascular endothelial growth factor receptor|||BIBF-1202|||Inhibitor

Nintedanib Impurity N1

894783-71-2

C30H31N5O4