ChemicalBook > CAS DataBase List > 2'-O-Methylguanosine

2'-O-Methylguanosine

Product Name
2'-O-Methylguanosine
CAS No.
2140-71-8
Chemical Name
2'-O-Methylguanosine
Synonyms
2'-OMe-G;2'-OMe-G;2'-OMe-Gr;2'-OMe-rG;2'-OMe-Gr;2'-OMe Guanosine;2'-OMe Guanosine;2'-O-METHYLGUANOSINE;2'-O-Methylguanosine;2 '- Methoxyguanosine
CBNumber
CB2276641
Molecular Formula
C11H15N5O5
Formula Weight
297.27
MOL File
2140-71-8.mol
More
Less

2'-O-Methylguanosine Property

Melting point:
227-231°C (dec.)
Density 
1.98±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Aqueous Base (Slightly), DMSO (Slightly),
pka
9?+-.0.20(Predicted)
form 
Powder
color 
White to Off-white
λmax
256 (pH 1)；258 (pH 11)
InChI
InChI=1S/C11H15N5O5/c1-20-7-6(18)4(2-17)21-10(7)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1
InChIKey
OVYNGSFVYRPRCG-KQYNXXCUSA-N
SMILES
OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)[C@H](OC)[C@@H]1O
CAS DataBase Reference
2140-71-8(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-22
Safety Statements 
26-36-60-36/37
HS Code 
29349990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
M2318
Product name
2'-O-Methylguanosine Hydrate
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$280
Updated
2024/03/01
TCI Chemical
Product number
M2318
Product name
2'-O-Methylguanosine Hydrate
Purity
>98.0%(HPLC)(T)
Packaging
200mg
Price
$89
Updated
2024/03/01
Alfa Aesar
Product number
J65770
Product name
2'-O-Methylguanosine, 99%
Packaging
1g
Price
$82.4
Updated
2024/03/01
Alfa Aesar
Product number
J65770
Product name
2'-O-Methylguanosine
Purity
99%
Packaging
250mg
Price
$20.2
Updated
2021/12/16
Cayman Chemical
Product number
21039
Product name
2'-O-Methylguanosine
Purity
≥98%
Packaging
250mg
Price
$57
Updated
2024/03/01
More
Less

2'-O-Methylguanosine Chemical Properties,Usage,Production

Description

2''-O-Methylguanosine is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase, using S-adenosyl-L-methionine (Item Nos. 16376 | 13956) as a substrate. Through its interaction with other modified nucleosides, 2''-O-methylguanosine is thought to stabilize the structure of the tRNA. 2''-O-Methylguanosine can also be found in rRNA. Normal and modified nucleosides, including 2''-O-methylguanosine, have been shown to be secreted by a natural suppressor cell line and induce apoptosis in K562/Molt4 target cells.

Chemical Properties

White Solid

Uses

Guanosine analog. Used for preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase.

Definition

ChEBI: Guanosine with the hydrogen on the hydroxyl at position C-2' substituted with a methyl group.

Synthesis

8-Thio-2'-O-methylguanosine (1 mmole) is dissolved in water and the solution is heated at reflux with Raney nickel for 6 h. The product is isolated by passing the solution through a short pad of celite and is further crystallizing to afford 2'-O-methylguanosine.

2'-O-Methylguanosine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2'-O-Methylguanosine Suppliers

Americas 1 Canada 2 China 210 Europe 1 Germany 2 India 8 Japan 1 Poland 1 Slovakia 1 South Korea 1 United Kingdom 6 United States 22 Global 256
Zhengzhou Chemprize Biotech Co., Ltd.
Tel
15981919713
Email
sales@chemprize.com
Country
China
ProdList
408
Advantage
58
Nanjing Baifuli Technology Co., Ltd.
Tel
25-25-58740604 15951658055
Fax
+86-25-58356858
Email
sales@unisyn.cn
Country
China
ProdList
561
Advantage
58
Wuhu Nuowei Chemical Technology Co., Ltd
Tel
0553-8233716 18055326116
Email
kendoll@cqpharm.com
Country
China
ProdList
645
Advantage
58
Jiangsu Synthgene Biotechnology Co.,Ltd.
Tel
18136497538
Email
znf@syngenebio.com
Country
China
ProdList
901
Advantage
58
Aikon International Limited
Tel
025-66113011 13155353615
Fax
(7)02557626880
Email
qzhang@aikonchem.com
Country
China
ProdList
15394
Advantage
58
Shandong utilizing biological technology co., LTD
Tel
15966937598
Fax
3407640895 3071519937
Email
3407650895@qq.com
Country
China
ProdList
1176
Advantage
58
Wuhu Huaren Science and Technology Co., Ltd.
Tel
0553-0553-0553-5842013-801-801 18155347026
Fax
086-553-5843138
Email
jinhuaren@huarensh.com
Country
China
ProdList
295
Advantage
64
HeFei ShenShen Medical Technology Co.,Ltd
Tel
15375050680; 15375050680
Email
gdz2.71828@163.com
Country
China
ProdList
17
Advantage
58
Allbiosyn Biotechnology Co.,LTD
Tel
18666985712
Email
info@allbiosyn.com
Country
China
ProdList
285
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Hongene Biotech Corporation
Tel
021-64757213
Fax
86-21-64700613
Email
info@hongene.com
Country
China
ProdList
672
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4552
Advantage
62
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Nanjing Credit Trading Co.,Ltd
Tel
025-52164950
Fax
025-86800069
Email
Googlexu_0114@sina.com
Country
China
ProdList
644
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11481
Advantage
59
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6479
Advantage
50
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4891
Advantage
55
Shanghai Synchem Pharma Co., ltd
Tel
21-619849051-1 18521059765
Email
synchempharma@aliyun.com
Country
China
ProdList
6463
Advantage
55
Wuhu Nuowei Chemical Technology Co., Ltd
Tel
0553-8233716 18055326116
Email
sales@nuowei-chem.com
Country
China
ProdList
951
Advantage
55
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Lancrix Chemicals
Tel
86-21-50817262
Fax
86-21-57712035
Email
sales@lancrix.com
Country
China
ProdList
1502
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Wuhan Wsem Biological Co., Ltd.
Tel
027-83778876 13667159345
Fax
027-83778876
Email
13667159345@163.com
Country
China
ProdList
1991
Advantage
55
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
Tel
027-50664929, 13971561712
Fax
027-50664927 / QQ: 3452835437
Email
hubxys2001@163.com
Country
China
ProdList
1437
Advantage
55
Hubei Hongxin Ruiyu Fine Chemical Co., Ltd.
Tel
027-65526929 15102793023
Fax
027-65526669
Email
hbhxry@foxmail.com
Country
China
ProdList
2006
Advantage
55
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
10007
Advantage
58
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9967
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19800
Advantage
60
LinkChem Co.,Ltd.
Tel
021-021-58950110 13124863828
Fax
021-20922272
Email
sales@linkchem.cn
Country
China
ProdList
2981
Advantage
58
Shanghai BaiShun Biological Technology Co., Ltd
Tel
021-37581181
Fax
021-57456066
Email
sales@chem-mall.com
Country
China
ProdList
10330
Advantage
58
Jiaxing Deyi Chemical Co., Ltd.
Tel
0573-86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8025
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
16509
Advantage
58
More
Less

View Lastest Price from 2'-O-Methylguanosine manufacturers

Hefei Huana Biomedical Technology Co.,Ltd.
Product
2'-O-Methylguanosine 2140-71-8
Price
US $0.00/g
Min. Order
1g
Purity
98%
Supply Ability
100kg
Release date
2023-05-10
Yunbio Tech Co.,Ltd.
Product
2'-O-Methylguanosine 2140-71-8
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
300KG per month
Release date
2023-03-04
Zhejiang Hengkang Pharmaceutical Co., Ltd.
Product
2'-O-Methylguanosine 2140-71-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
500kg per month
Release date
2022-12-27

2140-71-8, 2'-O-MethylguanosineRelated Search:

5'-Guanylic acid Methyl hesperidin Guanosine Guanosine 5'-monophosphate disodium salt Acyclovir 7,8-Dihydro-7-methylguanosine 2',3'-O-Isopropylideneguanosine 2',3',5'-Triacetylguanosine 1-METHYLGUANOSINE N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite N2-Isobutyryl-2'-O-Methyl-guanosine 2'-O-Methyl-N2-dimethylformamide-5'-O-DMT-Guanosine 2-Methylguanosine,N2-METHYLGUANOSINE,N-Methylguanosine N2-dimethylformamidine-2'-O-Methyl-guanosine 2'-O-Methyl-N2-Isobutyryl-5'-O-DMT-Guanosine 2'-C-Methylguanosine 2'-(N-Methylanthraniloyl)guanosine 3',5'-Cyclicmonophosphate, Sodium Salt 2',3',5-TRI-O-ACETYL-8-BROMOGUANOSINE

  • 2'-OMe-G
  • 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-3-methoxy-5-methylol-tetrahydrofuran-2-yl]-3H-purin-6-one
  • 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-3H-purin-6-one
  • 2-azanyl-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxy-oxolan-2-yl]-3H-purin-6-one
  • 2'-OMe Guanosine
  • 2'-O-METHYLGUANOSINE
  • 2'-O-Methyl-D-guanosine
  • 2'-O-Methyl Guanosine, >=99%
  • 2-aMino-9-[(2R,3R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)-3-Methoxyoxolan-2-yl]-6,9-dihydro-1H-purin-6-one
  • 2'-O-Methylguanosine Hydrate
  • 2'-OMe-Gr
  • 2'-O-MethylguanosineHydrate&gt
  • Guanosine, 2'-O-methyl-
  • 2'-OMe-rG
  • 2'-O-Methylguanosine USP/EP/BP
  • 2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one
  • 2’-O-Methylguanosine,RNA modified nucleoside Gm
  • Apoptosis,2’ OMe Guanosine,rRNA,inhibit,2’OMeGuanosine,Inhibitor,Nucleoside Antimetabolite/Analog,tRNA
  • 2 '- Methoxyguanosine
  • 2'-O-Methylguanosine
  • 2'-OMe Guanosine
  • 2'-OMe-G
  • 2'-OMe-Gr
  • 2'- 0 -Methylguanosine
  • 2140-71-8
  • C11H15N5O5xH2O
  • C11H15N5O5H2O
  • Nucleotides
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Heterocycles
  • Nucleosides
  • Modified（deoxy）nucleoside
  • Nucleosides-2'-OMe Nucleosides