ETHYL 2-(2-FORMYLAMINO-1,3-THIAZOL-4-YL)-2-OXOACETATE

Product Name: ETHYL 2-(2-FORMYLAMINO-1,3-THIAZOL-4-YL)-2-OXOACETATE
CAS No.: 64987-03-7
Chemical Name: ETHYL 2-(2-FORMYLAMINO-1,3-THIAZOL-4-YL)-2-OXOACETATE
Synonyms: EFTG;LABOTEST-BB LT00441209;Ethyl-2-(2-ForMylaMinothiazol-;ethyl 2-formamido-α-oxothiazol-4-acetate;ethyl 2-formamido-a-oxothiazol-4-acetate;ETHYL 2-(FORMYLAMINO)-4-THIAZOLEGLYOXYLATE;ethyl 2-(formylamino)-4-thiazoleglyoxalate;ETHYL 2-(FORMYLAMINO)THIAZOL-4-YLGLYOXYLATE;ethyl 2-formamido-alpha-oxothiazol-4-acetate;Ethyl2-(2-formamidothiazol-4-yl)-2-oxoacetate
CBNumber: CB2284428
Molecular Formula: C8H8N2O4S
Formula Weight: 228.23
MOL File: 64987-03-7.mol

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ETHYL 2-(2-FORMYLAMINO-1,3-THIAZOL-4-YL)-2-OXOACETATE Property

Melting point:: 232-234 °C
Boiling point:: 381.3±34.0 °C(Predicted)
Density: 1.5150 (rough estimate)
refractive index: 1.5690 (estimate)
storage temp.: 2-8°C
solubility: Chloroform (Slightly, Heated), DMSO (Slightly)
pka: 8.11±0.70(Predicted)
form: Solid
color: Light Yellow
CAS DataBase Reference: 64987-03-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 36/37/38-22
Safety Statements: 36/37/39-26-37/39
HS Code: 29341000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R751146
Product name: ETHYL 2-(FORMYLAMINO)-4-THIAZOLE-GLYOXYLATE
Purity: AldrichCPR
Packaging: 250MG
Price: $28.6
Updated: 2023/06/20

TRC

Product number: E717770
Product name: Ethyl2-(2-Formamidothiazol-4-yl)-2-oxoacetate
Packaging: 1g
Price: $145
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 64797
Product name: Ethyl2-(2-Formamidothiazol-4-yl)-2-oxoacetate
Packaging: 250mg
Price: $595
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0029885
Product name: ETHYL 2-(FORMYLAMINO)-4-THIAZOLEGLYOXYLATE
Purity: 95.00%
Packaging: 1G
Price: $627
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0029885
Product name: ETHYL 2-(FORMYLAMINO)-4-THIAZOLEGLYOXYLATE
Purity: 95.00%
Packaging: 5G
Price: $842.87
Updated: 2021/12/16

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ETHYL 2-(2-FORMYLAMINO-1,3-THIAZOL-4-YL)-2-OXOACETATE Chemical Properties,Usage,Production

Chemical Properties

light yellow powder

Uses

Ethyl 2-(2-Formamidothiazol-4-yl)-2-oxoacetate is an intermediate formed in the synthesis of Cefixime Ethyl Ester Sodium Salt (C242830), an ester impurity of the third generation cephalosporin antibiotic, Cefixime (C242800).

Synthesis

A mixture of ethylene acetate tetrahydrate (120 g), acetic acid (1000 ml) and acetic anhydride (100 ml) was stirred in an oil bath heated to 130C to 135C for 20 minutes and potassium permanganate (20 g) was added to the mixture over a period of 5 minutes with stirring at 105C to 110C. The mixture was then stirred further at 130C to 135C for 30 minutes. The mixture was cooled to room temperature and ethyl 2-(2-formylaminothiazol-4-yl)acetate (53.5 g) was added to the mixture. The mixture was then stirred by introducing air at a rate of 6000 ml at 38C to 40C for 15 hrs. per minute. After the reaction, the precipitate was collected by filtration. The precipitate was washed sequentially with acetic acid and water and then dried to give ethyl 2-(2-formylaminothiazol-4-yl)glyoxylate (ethylamino thiazole, 41.5 g) with a melting point of 232-233C (decomposition).

ETHYL 2-(2-FORMYLAMINO-1,3-THIAZOL-4-YL)-2-OXOACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHYL 2-(2-FORMYLAMINO-1,3-THIAZOL-4-YL)-2-OXOACETATE Suppliers

Belgium 2 China 46 Germany 2 India 3 Japan 1 Slovakia 1 United Kingdom 7 United States 20 Global 82

J & K SCIENTIFIC LTD.

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View Lastest Price from ETHYL 2-(2-FORMYLAMINO-1,3-THIAZOL-4-YL)-2-OXOACETATE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Ethyl 2-(forMylaMino)-4-thiazoleglyoxylate 64987-03-7
Price: US $0.00-0.00/KG
Min. Order: 5mg
Purity: 99%HPLC
Supply Ability: 2000tons
Release date: 2020-01-06

64987-03-7, ETHYL 2-(2-FORMYLAMINO-1,3-THIAZOL-4-YL)-2-OXOACETATERelated Search:

Sodium ethylxanthogenate Ethyl maltol Methyl 2-oxoacetate 4-Methylthiazole Ethyl 2-amino-4-thiazoleacetate Pyruvic acid (2-Formamido-1,3-thiazol-4-yl)glyoxylic acid 2-Aminothiazole-4-acetic acid 2-Formamidothiazol-4-acetic acid 2-(2-Aminothiazol-4-yl)glyoxylic acid Ethyl 2-formamidothiazol-4-acetate Ethyl 2-(2-aminothiazol-4-yl)glyoxylate 2-Amino-4-methylthiazole 2-(1,3-thiazol-4-yl)acetic acid 3-CHLORO-2-METHYLBENZYLAMINE Ethyl pyruvate Thiazole-4-carboxaldehyde Ethyl glyoxalate

(2-FORMYLAMINOTHIAZOL-4-YL)-OXO-ACETIC ACID ETHYL ESTER

LABOTEST-BB LT00441209

ETHYL 2-(FORMYLAMINO)-4-THIAZOLEGLYOXYLATE

ETHYL 2-(2-FORMAMIDO-1,3-THIAZOL-4-YL)-2-OXO-ACETATE

ETHYL 2-(2-FORMYLAMINO-1,3-THIAZOL-4-YL)-2-OXOACETATE

ETHYL-2-(2-FORMYLAMINO-4-THIAZOLE-4-YL)-1-OXY ACETATE

ETHYL 2-(2-FORMYLAMINOTHIAZOL-4-YL) GLYOXYLATE

ETHYL 2-(FORMYLAMINO)THIAZOL-4-YLGLYOXYLATE

ethyl 2-(formylamino)-4-thiazoleglyoxalate

2-(Formylamino)-α-oxo-4-thiazoleacetic acid ethyl ester

2-[2-(Formylamino)-4-thiazolyl]-2-oxoacetic acid ethyl ester

ethyl 2-formamido-alpha-oxothiazol-4-acetate

Ethyl-2-(2-Formylamino-4-Thiazole-4-Yl)-1-Oxo-Acetate

Ethyl2-(2-formamidothiazol-4-yl)-2-oxoacetate

Ethyl [2-(formylamino)-1,3-thiazol-4-yl](oxo)acetate

N-{4-[Ethoxy(oxo)acetyl]-1,3-thiazol-2-yl}formamide

N-{4-[Ethoxy(oxo)acetyl]-1,3-thiazol-2-yl}formamide, 4-[Ethoxy(oxo)acetyl]-2-(formylamino)-1,3-thiazole

Ethyl-2-(2-ForMylaMinothiazol-

ethyl 2-formamido-α-oxothiazol-4-acetate

Ethyl-2 (2-Formylamino-Thiazole-4-Yl) - Glyoxylate

EFTG Ethyl 2-(2-formylaminothiazol-4-yl) glyoxylate

4-Thiazoleacetic acid, 2-(formylamino)-α-oxo-, ethyl ester

EFTG

2-(formylamino) thiazolyl-4-glyoxylic acid ethyl ester

ethyl 2-formamido-a-oxothiazol-4-acetate

64987-03-7

C8H8N2O4S