ChemicalBook > CAS DataBase List > Sulfamethazine sodium salt

Sulfamethazine sodium salt

Product Name: Sulfamethazine sodium salt
CAS No.: 1981-58-4
Chemical Name: Sulfamethazine sodium salt
Synonyms: sulmet;vesadin;bovibol;Sulfoxine 33;sodiumsulfadimidine;sodiumsulfametazine;SULFADIMIDINE SODIUM;sulfamethazinesodium;sodiumsulfamethazine;sodiumsulfamezathine
CBNumber: CB2284761
Molecular Formula: C12H15N4NaO2S
Formula Weight: 302.33
MOL File: 1981-58-4.mol

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Sulfamethazine sodium salt Property

Melting point:: >288°C (dec.)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: H2O: soluble50mg/mL
form: powder
color: white to off-white
Water Solubility: H2O: soluble 50mg/mL
Merck: 14,8915
Stability:: Hygroscopic
InChI: InChI=1S/C12H14N4O2S.Na.H/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11;;/h3-7H,13H2,1-2H3,(H,14,15,16);;
InChIKey: WIVZAHIZHZEEOX-UHFFFAOYSA-N
SMILES: S(C1C=CC(N)=CC=1)(=O)(=O)NC1=NC(C)=CC(C)=N1.[NaH]
CAS DataBase Reference: 1981-58-4
EPA Substance Registry System: Benzenesulfonamide, 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-, monosodium salt (1981-58-4)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 36
WGK Germany: 3
RTECS: WO9300000
HS Code: 2933.59.8000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S5637
Product name: Sulfamethazine sodium salt
Purity: ≥98%
Packaging: 25g
Price: $51.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: S5637
Product name: Sulfamethazine sodium salt
Purity: ≥98%
Packaging: 100g
Price: $74.4
Updated: 2025/07/31

TCI Chemical

Product number: S0583
Product name: Sulfamethazine Sodium Salt
Purity: >97.0%(HPLC)(N)
Packaging: 25g
Price: $36
Updated: 2025/07/31

TCI Chemical

Product number: S0583
Product name: Sulfamethazine Sodium Salt
Purity: >97.0%(HPLC)(N)
Packaging: 500g
Price: $191
Updated: 2025/07/31

TRC

Product number: S699080
Product name: Sulfamethazine Sodium Salt
Packaging: 10g
Price: $70
Updated: 2021/12/16

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Sulfamethazine sodium salt Chemical Properties,Usage,Production

Chemical Properties

White or milky white crystalline powder, odorless or almost odorless, easily soluble in water, slightly soluble in ethanol.

Uses

Antibacterial;Inhibitor of folic acid synthesis

Biological Activity

Sulfamethazine is an antimicrobial sulfur drug th at blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfamethazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It induces CYP3A4 expression and is acetylated by N-acetyltransferase. It exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11. Sulfamethazine is bacteriostatic.

in vivo

Sulfamethazine (80 mg/kg; intravenous injection; healthy female pigs) treatment significantly reduces α, β and AUC_0->∞, significantly increases t_1/2α, Vd and CIB, and upon a single intramuscular administration of 80 mg/kg of Sulfamethazine the absolute bioavailability in pigs is 1.01^[1].

Animal Model:	19 healthy female pigs (6-week-old, 4.5-6.2 kg)^[1]
Dosage:	80 mg/kg
Administration:	Intravenous injection (Pharmacokinetic study)
Result:	The half-life in distribution phase is 0.23 h and half-lifes in eliminations phase is 9.8 h. α, β and the AUC_0->∞ were significantly decreased and t_1/2α, Vd and CIB were significantly increased, and the absolute bioavailability in pigs is 1.01.

Sulfamethazine sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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Sulfamethazine sodium salt Suppliers

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View Lastest Price from Sulfamethazine sodium salt manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Sulfamethazine sodium salt 1981-58-4
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%-101%;BP
Supply Ability: 1000KGS
Release date: 2021-07-05

Sinoway Industrial co., ltd.

Product: Sulfadimidine Sodium 1981-58-4
Price: US $0.00/Kg/Bag
Min. Order: 2Kg/Bag
Purity: 99% up, High Density
Supply Ability: 20 tons
Release date: 2021-07-15

Henan Suikang Pharmaceutical Co.,Ltd.

Product: Sulfamethazine sodium salt 1981-58-4
Price: US $0.00/kg
Min. Order: 25kg
Purity: ＞99%
Supply Ability: 10tons
Release date: 2024-04-25

1981-58-4, Sulfamethazine sodium saltRelated Search:

Dimethyl phthalate Sodium sulfadiazine Dimethyl sulfoxide Diclofenac sodium Sodium acetate Sulfanilamide Dimethyl carbonate p-Anisidine Sodium chloride N,N-Dimethylformamide 4-Aminobenzoic acid Sulfanilic acid Dimethyl fumarate Aniline Dacthal Dimethyl ether 2-(4-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine Sodium benzoate

(n(sup1)-(4,6-dimethyl-2-pyrimidinyl)sulfanilamido)-sodiu

4-amino-n-(4,6-dimethyl-2-pyrimidinyl)-benzenesulfonamidmonosodiumsalt

sodiumsulphamezathine

sulfamethazinesodium

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vesadin

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SULFADIMIDINE SODIUM

SULFAMETHAZINE SODIUM SALT

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bovibol

n(sup1)-(4,6-dimethyl-2-pyrimidinyl)-sulfanilamidmonosodiumsalt

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sodiumsulfametazine

sodiumsulfamethazine

sodiumsulfamethiazine

sodiumsulfamezathine

Sodium Sulfamethazine 4-Amino-N-(4,6-dimethyl-2-pyrimidyl)benzenesulfonamide Sodium Salt

SulfadiMidine Base(SodiuM)

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Sulfadimethyldiazine Sodium Salt

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sodium,(4-aminophenyl)sulfonyl-(4,6-dimethylpyrimidin-2-yl)azanide

Sulfadimidine SodiumQ: What is Sulfadimidine Sodium Q: What is the CAS Number of Sulfadimidine Sodium Q: What is the storage condition of Sulfadimidine Sodium Q: What are the applications of Sulfadimidine Sodium

Sodium ((4-aminophenyl)sulfonyl)(4,6-dimethylpyrimidin-2-yl)amide

Sulfadimidine Sodium Powder

Sulfadimethyldiazine Sodium Salt|||Sulfamethazine sodium salt

Sulfamethazine sodium, 10 mM in DMSO

(4-aminophenyl)sulfonyl-(4,6-dimethylpyrimidin-2-yl)azanide

1981-58-4

C12H14N4NaO2S

C12H13N4NaO2S

C12H13N4O2SNa

Antibiotics

Antibiotics N-S

Antibiotics A to Z

BioChemical

Animal medication

Inhibitors

API

sulfonamides

Pharmaceutical intermediate

Antibiotics for Research and Experimental Use

Biochemistry

Sulfonamides (Antibiotics for Research and Experimental Use)

1981-58-4