AMCA-NHS
- Product Name
- AMCA-NHS
- CAS No.
- 113721-87-2
- Chemical Name
- AMCA-NHS
- Synonyms
- AMCA-OSU;AMCA-NHS;AMCA-H NHS;7-AMCA NHS ester;AMCA N-succinimidyl ester;AMCA-H N-succinimidyl ester;7-AMINO-4-METHYL-3-COUMARINYLACETYL;7-(DiMethylaMino)couMarin-4-aceticcid-NHS;7-(Dimethylamino)coumarin-4-acetic acid-NHS;SUCCINIMIDYL-7-AMINO-4-METHYLCOUMARIN-3-ACETATE
- CBNumber
- CB2298838
- Molecular Formula
- C16H14N2O6
- Formula Weight
- 330.29
- MOL File
- 113721-87-2.mol
AMCA-NHS Property
- Boiling point:
- 559.4±60.0 °C(Predicted)
- Density
- 1.50±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMF: soluble
- pka
- 1.69±0.20(Predicted)
- form
- A solid
- Appearance
- Light yellow solid
- ex/em
- 353/455 nm
- ε(extinction coefficient)
- 19000 L⋅mol−1⋅cm−1
- BRN
- 9007679
- InChI
- InChI=1S/C16H14N2O6/c1-8-10-3-2-9(17)6-12(10)23-16(22)11(8)7-15(21)24-18-13(19)4-5-14(18)20/h2-3,6H,4-5,7,17H2,1H3
- InChIKey
- ILKQVTIMOGNSAS-UHFFFAOYSA-N
- SMILES
- C1(=O)OC2=CC(N)=CC=C2C(C)=C1CC(ON1C(=O)CCC1=O)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 08450
- Product name
- 7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester
- Purity
- BioReagent, suitable for fluorescence, ≥90% (HPLC)
- Packaging
- 5mg
- Price
- $297.35
- Updated
- 2025/07/31
- Product number
- A634433
- Product name
- 7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester
- Packaging
- 5mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- A634433
- Product name
- 7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester
- Packaging
- 10mg
- Price
- $385
- Updated
- 2021/12/16
- Product number
- FA170610
- Product name
- 7-Amino-4-methyl-3-coumarinacetic acid?N-succinimidyl ester
- Packaging
- 25mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- BIM107
- Product name
- Succinimidyl-7-amino-4-methylcoumarin-3-acetate
- Packaging
- 50mg
- Price
- $145
- Updated
- 2021/12/16
AMCA-NHS Chemical Properties,Usage,Production
Description
Activated NHS-ester of AMCA (aminomethyl coumarin acetate) dye. This NHS ester is an amine-reactive dye for labeling of amine groups in proteins, peptides, amino-modified oligos, and other target molecules.
AMCA is one of the brightest blue fluorescent dyes. This fluorophore has a relatively large Stoke’s shift, high resistance to photobleaching, and pH-independent fluorescence from pH 4 to 10. AMCA is a widely used fluorophore for multiple-color labeling due to its minimal fluorescence overlap with green- and longer wavelength-emitting fluorescent dyes.
Chemical Properties
Appearance: Pale yellow solid
ex/em: 353/455 nm
Extinction coefficient (ε): 19000 L??mol??1??cm??1
Uses
AMCA-H NHS ester reacts with primary amines at pH 7.0-9.0. Suitable for labeling lysyl residues in proteins.
Abs/Em Maxima
348/435 nm
Fluoresene quantum yield
0.91
Extinction Coefficient
17400
CF260
0.16
CF280
0.13
AMCA-NHS Preparation Products And Raw materials
Raw materials
Preparation Products
AMCA-NHS Suppliers
- Tel
- --
- Fax
- --
- Country
- Europe
- ProdList
- 1780
- Advantage
- 38
View Lastest Price from AMCA-NHS manufacturers
- Product
- (2,5-dioxopyrrolidin-1-yl) 2-(7-amino-4-methyl-2-o 113721-87-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10 tons/month
- Release date
- 2020-01-09