ChemicalBook > CAS DataBase List > N,N,N',N'-Tetramethyl-1,4-phenylenediamine

N,N,N',N'-Tetramethyl-1,4-phenylenediamine

Product Name
N,N,N',N'-Tetramethyl-1,4-phenylenediamine
CAS No.
100-22-1
Chemical Name
N,N,N',N'-Tetramethyl-1,4-phenylenediamine
Synonyms
tl85;TL 85;TMPPD;WursterBlue];wurster’sblue;Wurster's blue;p-Bis(dimethylamino)benzene;Tetramethyl-p-phenyldiamine;1,4-bis(dimethylamino)-benzen;1,4-BIS(DIMETHYLAMINO)BENZENE
CBNumber
CB2300445
Molecular Formula
C10H16N2
Formula Weight
164.25
MOL File
100-22-1.mol
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N,N,N',N'-Tetramethyl-1,4-phenylenediamine Property

Melting point:
49-51 °C(lit.)
Boiling point:
260 °C(lit.)
Density 
0.9743 (rough estimate)
refractive index 
1.5700 (estimate)
Flash point:
>230 °F
storage temp. 
Store below +30°C.
form 
powder
pka
5.92±0.12(Predicted)
color 
off-white to gray
Water Solubility 
slightly in cold, more in hot water
Sensitive 
Air & Light Sensitive
Merck 
14,9228
BRN 
1564025
Stability:
Stable, but may be air or light sensitive. Combustible. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.
CAS DataBase Reference
100-22-1(CAS DataBase Reference)
NIST Chemistry Reference
1,4-Benzenediamine, N,N,N',N'-tetramethyl-(100-22-1)
EPA Substance Registry System
N,N,N',N'-Tetramethyl-p-phenylenediamine (100-22-1)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-40-36/37/38
Safety Statements 
28-28A-36-26-22
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
1
RTECS 
ST4200000
10
TSCA 
Yes
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
29215190
Toxicity
LD50 oral in bird - wild: 23700ug/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T7394
Product name
N,N,N′,N′-Tetramethyl-p-phenylenediamine
Purity
99%, powder
Packaging
5g
Price
$112
Updated
2024/03/01
Sigma-Aldrich
Product number
T7394
Product name
N,N,N′,N′-Tetramethyl-p-phenylenediamine
Purity
99%, powder
Packaging
25g
Price
$285
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21101
Product name
N,N,N′,N′-Tetramethyl-1,4-phenylenediamine
Purity
for synthesis
Packaging
5G
Price
$76.7
Updated
2024/03/01
Sigma-Aldrich
Product number
8.21101
Product name
N,N,N′,N′-Tetramethyl-1,4-phenylenediamine
Purity
for synthesis
Packaging
25g
Price
$254
Updated
2024/03/01
Alfa Aesar
Product number
L00559
Product name
N,N,N',N'-Tetramethyl-p-phenylenediamine, 98+%
Packaging
10g
Price
$61.5
Updated
2024/03/01
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N,N,N',N'-Tetramethyl-1,4-phenylenediamine Chemical Properties,Usage,Production

Chemical Properties

purple to brown crystalline powder

Uses

N,N,N',N'-Tetramethyl-p-phenylenediamine is a reducing co-substrate for heme peroxidases. It is used for detection of peroxidases on polyacrylamide gels.

Uses

In the form of the hydrochloride as a reagent in analytical chemistry.

Synthesis Reference(s)

The Journal of Organic Chemistry, 29, p. 488, 1964 DOI: 10.1021/jo01025a506

General Description

Leaflets or a drab green solid.

Air & Water Reactions

N,N,N',N'-Tetramethyl-1,4-phenylenediamine may be sensitive to air and heat. . Insoluble in water.

Reactivity Profile

N,N,N',N'-Tetramethyl-1,4-phenylenediamine can burn in air to give toxic NOx gases . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition N,N,N',N'-Tetramethyl-1,4-phenylenediamine emits toxic fumes. It is an irritant.

Fire Hazard

N,N,N',N'-Tetramethyl-1,4-phenylenediamine is probably combustible.

Safety Profile

Poison by ingestion. Moderatelytoxic by inhalation. Mutation data reported. When heatedto decomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise the amine from pet ether or water. It can be sublimed or dried carefully in a vacuum line, and stored in the dark under nitrogen. It has been recrystallised from its melt. [Beilstein 13 H 74, 13 I 22, 13 II 40, 13 III 111, IV 107.]

N,N,N',N'-Tetramethyl-1,4-phenylenediamine Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N,N',N'-Tetramethyl-1,4-phenylenediamine Suppliers

Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
Kanto Chemical Co., Inc.
Tel
--
Fax
--
Email
reag-info@gms.kanto.co.jp
Country
Japan
ProdList
6756
Advantage
74
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View Lastest Price from N,N,N',N'-Tetramethyl-1,4-phenylenediamine manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
N,N,N",N"-Tetramethyl-1,4-phenylenediamine 100-22-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
N,N,N",N"-Tetramethyl-1,4-phenylenediamine 100-22-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Career Henan Chemical Co
Product
N,N,N',N'-Tetramethyl-1,4-phenylenediamine 100-22-1
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-04

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