ChemicalBook > CAS DataBase List > NSC 361680

NSC 361680

Product Name
NSC 361680
CAS No.
5961-83-1
Chemical Name
NSC 361680
Synonyms
NSC 361680;Di-Acid-PEG1;Bis-PEG1-COOH;Bis-PEG1-acid;CAS_5961-83-1;3,3'-Oxydipropionic acid;3,3'-oxydipropanoic acid;Bis(2-carboxyethyl) ether;3,3'-Oxybis[propanoic acid];Propanoic acid, 3,3'-oxybis-
CBNumber
CB23052048
Molecular Formula
C6H10O5
Formula Weight
162.14
MOL File
5961-83-1.mol
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NSC 361680 Property

Melting point:
60-61 °C
Boiling point:
198-200 °C(Press: 1-2 Torr)
Density 
1.316±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Aqueous Base (Slightly), Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
pka
3.96±0.10(Predicted)
form 
Solid
color 
Pale Yellow to Light Yellow
InChI
InChI=1S/C6H10O5/c7-5(8)1-3-11-4-2-6(9)10/h1-4H2,(H,7,8)(H,9,10)
InChIKey
FOSIWKADJDNVMJ-UHFFFAOYSA-N
SMILES
O(CCC(O)=O)CCC(O)=O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B568230
Product name
Bis-PEG1-acid
Packaging
10mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
7548BA
Product name
3,3'-Oxydipropanoicacid
Packaging
100mg
Price
$279
Updated
2021/12/16
Apolloscientific
Product number
BIPG1246
Product name
Bis-PEG1-acid
Packaging
250mg
Price
$377
Updated
2021/12/16
BroadPharm
Product number
BP-21831
Product name
Bis-PEG1-acid
Purity
96%
Packaging
5G
Price
$890
Updated
2021/12/16
AK Scientific
Product number
7548BA
Product name
3,3'-Oxydipropanoicacid
Packaging
10g
Price
$2603
Updated
2021/12/16
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NSC 361680 Chemical Properties,Usage,Production

Description

Bis-PEG1-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Bis-PEG1-acid is a PEG-based PROTAC linker and can be used in the synthesis of PROTACs as BCL-xL degraders and anticancer agents with low platelet toxicity.

IC 50

PEGs

NSC 361680 Preparation Products And Raw materials

Raw materials

Preparation Products

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NSC 361680 Suppliers

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View Lastest Price from NSC 361680 manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Bis-PEG1-acid 5961-83-1
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-23

5961-83-1, NSC 361680Related Search:


  • 3,3'-Oxybis[propanoic acid]
  • 3,3'-Oxydipropionic acid
  • Bis(2-carboxyethyl) ether
  • NSC 361680
  • Bis-PEG1-acid
  • 3-(2-carboxyethoxy)propanoic acid
  • Propanoic acid, 3,3'-oxybis-
  • CAS_5961-83-1
  • 3-(2-carboxyethoxy)propionic acid
  • 3-(2-carboxyethyloxy)propanoic acid
  • Bis-PEG1-COOH
  • 3,3'-oxydipropanoic acid
  • Di-Acid-PEG1
  • 5961-83-1