NSC 361680
- Product Name
- NSC 361680
- CAS No.
- 5961-83-1
- Chemical Name
- NSC 361680
- Synonyms
- NSC 361680;Di-Acid-PEG1;Bis-PEG1-COOH;Bis-PEG1-acid;CAS_5961-83-1;3,3'-Oxydipropionic acid;3,3'-oxydipropanoic acid;Bis(2-carboxyethyl) ether;3,3'-Oxybis[propanoic acid];Propanoic acid, 3,3'-oxybis-
- CBNumber
- CB23052048
- Molecular Formula
- C6H10O5
- Formula Weight
- 162.14
- MOL File
- 5961-83-1.mol
NSC 361680 Property
- Melting point:
- 60-61 °C
- Boiling point:
- 198-200 °C(Press: 1-2 Torr)
- Density
- 1.316±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- Aqueous Base (Slightly), Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
- pka
- 3.96±0.10(Predicted)
- form
- Solid
- color
- Pale Yellow to Light Yellow
- InChI
- InChI=1S/C6H10O5/c7-5(8)1-3-11-4-2-6(9)10/h1-4H2,(H,7,8)(H,9,10)
- InChIKey
- FOSIWKADJDNVMJ-UHFFFAOYSA-N
- SMILES
- O(CCC(O)=O)CCC(O)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B568230
- Product name
- Bis-PEG1-acid
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 7548BA
- Product name
- 3,3'-Oxydipropanoicacid
- Packaging
- 100mg
- Price
- $279
- Updated
- 2021/12/16
- Product number
- BIPG1246
- Product name
- Bis-PEG1-acid
- Packaging
- 250mg
- Price
- $377
- Updated
- 2021/12/16
- Product number
- BP-21831
- Product name
- Bis-PEG1-acid
- Purity
- 96%
- Packaging
- 5G
- Price
- $890
- Updated
- 2021/12/16
- Product number
- 7548BA
- Product name
- 3,3'-Oxydipropanoicacid
- Packaging
- 10g
- Price
- $2603
- Updated
- 2021/12/16
NSC 361680 Chemical Properties,Usage,Production
Description
Bis-PEG1-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Bis-PEG1-acid is a PEG-based PROTAC linker and can be used in the synthesis of PROTACs as BCL-xL degraders and anticancer agents with low platelet toxicity.
IC 50
PEGs
NSC 361680 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from NSC 361680 manufacturers
- Product
- Bis-PEG1-acid 5961-83-1
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-23