ML 154

Product Name: ML 154
CAS No.: 1345964-89-7
Chemical Name: ML 154
Synonyms: ML 154;NCGC 84 (ML154);ML 154,inhibit,Inhibitor,ML-154,NCGC-84,NCGC84,addiction,food disorder,NCGC 84,NPSR,anxiety,ML154;3-(Diphenylphosphinothioyl)-2-methyl-1-[(2E)-3-phenyl-2-propen-1-yl]imidazo[1,2-a]pyridinium bromide
CBNumber: CB23146330
Molecular Formula: C29H26BrN2PS
Formula Weight: 545.48
MOL File: 1345964-89-7.mol

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ML 154 Property

storage temp.: Store at -20°C
solubility: DMSO: 10 mg/ml, sonicated
form: A solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 30200
Product name: ML154
Packaging: 1mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 30200
Product name: ML154
Packaging: 10mg
Price: $302
Updated: 2024/03/01

Cayman Chemical

Product number: 30200
Product name: ML154
Packaging: 5mg
Price: $235
Updated: 2024/03/01

Tocris

Product number: 5161
Product name: ML154
Purity: ≥99%(HPLC)
Packaging: 10
Price: $264
Updated: 2021/12/16

Tocris

Product number: 5161
Product name: ML154
Purity: ≥99%(HPLC)
Packaging: 50
Price: $1078
Updated: 2021/12/16

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ML 154 Chemical Properties,Usage,Production

Uses

ML 154 is a potent neuropeptide S receptor antagonist which may be used in the treatment of sleep, anxiety and addiction disorders.

in vivo

ML154 (NCGC84; 1 mg/kg; i.p; once) blocks alcohol-induced ERK-phosphorylation in the rat central amygdala, a region involved in regulation of alcohol intake. ML154 also decreases operant alcohol self-administration, and lowers motivation for alcohol reward as measured using progressive ratio responding^[1].

Animal Model:	Male Wistar rats (300-350 g) injected with alcohol^[1]
Dosage:	1 mg/kg (10% Solutol, 10% N,N-dimethylacetamide, and 80% 10 mM PBS, pH 7.4)
Administration:	Intraperitoneal injection; once
Result:	Inhibited alcohol-induced central ERK phosphorylation in vivo.

storage

Store at +4°C

ML 154 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML 154 Suppliers

China 25 United Kingdom 1 United States 6 USA 1 Global 33

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
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Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
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TargetMol Chemicals Inc.

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Email: marketing@targetmol.com
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InvivoChem

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Nantong Hi-Future Biotechnology Co., Ltd

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InvivoChem

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TargetMol Chemicals Inc.

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Shanghai Tachizaki Biomedical Research Center

Tel: 18014399201
Email: sales@chemlab-tachizaki.com
Country: China
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1345964-89-7, ML 154Related Search:

ML385 ML365 ML349 ML337 8-ethyl-5-oxo-2-[4-[[3-(trifluoromethyl)phenyl]carbamothioyl]piperazin-1-yl]pyrido[2,3-d]pyrimidine-6-carboxylic acid ML364

ML 154

3-(Diphenylphosphinothioyl)-2-methyl-1-[(2E)-3-phenyl-2-propen-1-yl]imidazo[1,2-a]pyridinium bromide

NCGC 84 (ML154)

ML 154,inhibit,Inhibitor,ML-154,NCGC-84,NCGC84,addiction,food disorder,NCGC 84,NPSR,anxiety,ML154

1345964-89-7

1345964-89-4

C29H26N2PSBr