ChemicalBook > CAS DataBase List > 4-CHLORO-3-IODOQUINOLINE

4-CHLORO-3-IODOQUINOLINE

Product Name
4-CHLORO-3-IODOQUINOLINE
CAS No.
590371-90-7
Chemical Name
4-CHLORO-3-IODOQUINOLINE
Synonyms
4-CHLORO-3-IODOQUINOLINE;1,4-CHLORO-3-IODOQUINOLINE;Quinoline, 4-chloro-3-iodo-
CBNumber
CB2325143
Molecular Formula
C9H5ClIN
Formula Weight
289.5
MOL File
590371-90-7.mol
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4-CHLORO-3-IODOQUINOLINE Property

storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
solid
Appearance
White to off-white Solid
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Safety

Hazard Codes 
Xn
Risk Statements 
22
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SYX00306
Product name
4-Chloro-3-iodo-quinoline
Packaging
1g
Price
$185
Updated
2025/07/31
TRC
Product number
C367308
Product name
4-Chloro-3-iodoquinoline
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
C367308
Product name
4-Chloro-3-iodoquinoline
Packaging
100mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
Y1203
Product name
4-Chloro-3-iodo-quinoline
Packaging
1g
Price
$97
Updated
2021/12/16
AK Scientific
Product number
J96930
Product name
4-Chloro-3-iodo-quinoline
Packaging
5g
Price
$295
Updated
2021/12/16
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4-CHLORO-3-IODOQUINOLINE Chemical Properties,Usage,Production

Synthesis

64965-48-6

590371-90-7

Synthesis of 4-chloro-3-iodoquinoline (Compound 16): 4-hydroxy-3-iodoquinoline (Compound 15, 1000 mg, 3.69 mmol) was dissolved in 25 mL of phosphorus oxychloride (POCl3). The reaction mixture was stirred at 100°C for 2 hours. The reaction progress was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the solvent was removed by evaporation under reduced pressure, followed by the addition of ice water. The solid product was collected by filtration and dried under vacuum to give compound 16 as a white solid (900 mg, 85% yield).

References

[1] ChemMedChem, 2014, vol. 9, # 4, p. 719 - 723
[2] Patent: WO2015/95780, 2015, A1. Location in patent: Page/Page column 21; 35
[3] Journal of the American Chemical Society, 1946, vol. 68, p. 2570,2573
[4] Patent: WO2011/22216, 2011, A1. Location in patent: Page/Page column 30

4-CHLORO-3-IODOQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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590371-90-7, 4-CHLORO-3-IODOQUINOLINERelated Search:


  • 4-CHLORO-3-IODOQUINOLINE
  • Quinoline, 4-chloro-3-iodo-
  • 1,4-CHLORO-3-IODOQUINOLINE
  • 590371-90-7