Semaglutide intermediate

Product Name: Semaglutide intermediate
CAS No.: 1118767-15-9
Chemical Name: Semaglutide intermediate
Synonyms: Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OSu;Carbaryl Impurity 1;tBuO-Ste-yGlu(OtBu)-;Somalutide side chain;Semaglutide Impurity 17;Semaglutide Impurity 45;tBuO-Ste-E(AEEA-AEEA-OSu)-OtBu;tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu;tBuO-C18-Glu(AEEA-AEEA-OSu)-OtBu;tBuO-C18-γGlu(tBu)-AEEA-AEEA-OSU
CBNumber: CB23352999
Molecular Formula: C47H82N4O15
Formula Weight: 943.17
MOL File: 1118767-15-9.mol

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Semaglutide intermediate Property

Density: 1.15±0.1 g/cm3(Predicted)
pka: 14.18±0.46(Predicted)
InChI: InChI=1S/C47H82N4O15/c1-46(2,3)64-43(57)22-20-18-16-14-12-10-8-7-9-11-13-15-17-19-21-39(53)50-37(45(59)65-47(4,5)6)23-24-38(52)48-27-29-60-31-33-62-35-40(54)49-28-30-61-32-34-63-36-44(58)66-51-41(55)25-26-42(51)56/h37H,7-36H2,1-6H3,(H,48,52)(H,49,54)(H,50,53)/t37-/m0/s1
InChIKey: ZYJILBKLUVJVKQ-QNGWXLTQSA-N
SMILES: C(ON1C(=O)CCC1=O)(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@@H](C(OC(C)(C)C)=O)NC(=O)CCCCCCCCCCCCCCCCC(OC(C)(C)C)=O

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Hazard and Precautionary Statements (GHS)

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Semaglutide intermediate Chemical Properties,Usage,Production

Description

Semaglutide intermediates play a crucial role in the synthesis and development of Semaglutide, a potent GLP-1 receptor agonist.

Uses

Semaglutide intermediate is an intermediate of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes.

Synthesis

Somalutide side chain is synthesized from tetradecanedioic acid by condensation, reduction, ring-opening and Boc monoprotection of first synthesizing the intermediate mono-tert-butyl octadecanedioate, and then by further condensation reaction of the intermediate.

Semaglutide intermediate Preparation Products And Raw materials

Raw materials

Preparation Products

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Semaglutide intermediate Suppliers

China 125 Japan 1 United States 2 Global 128

Hubei Kele Fine Chemical Co., Ltd

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Zhejiang Bolang New Material Co., LTD

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View Lastest Price from Semaglutide intermediate manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu 1118767-15-9
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle , 10g/bottle, 100g/bottle
Release date: 2024-07-26

Shaanxi Dideu New Materials Co. Ltd

Product: Semaglutide intermediate 1118767-15-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1000KGS
Release date: 2024-11-12

Suzhou Nordica Biopharma CO.,LTD

Product: Semaglutide intermediate 1118767-15-9
Price: US $0.00-0.00/g
Min. Order: 10g
Purity: 0.99
Supply Ability: 1 tons
Release date: 2024-11-15

1118767-15-9, Semaglutide intermediateRelated Search:

Semaglutide tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu OCTADECANEDIOIC ACID Boc-His(Trt)-Aib-OH Octadecanedioic acid mono-tert-butyl ester Fmoc-8-amino-3,6-dioxaoctanoic acid

Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OSu

3,6,12,15-Tetraoxa-9,18,23-triazahentetracontanedioic acid, 22-[(1,1-dimethylethoxy)carbonyl]-10,19,24-trioxo-, 41-(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester, (22S)-

tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu

17-((S)-1-tert-Butoxycarbonyl-3-{2-[2-({2-[2-(2,5-dioxopyrrolidin-1-yloxycarbonylmethoxy)ethoxy]ethylcarbamoyl}methoxy)ethoxy]-ethylcarbamoyl}propylcarbamoyl)heptadecanoic acid tert-butyl ester

21,39-di-tert-Butyl 1-(2,5-dioxopyrrolidin-1-yl) (S)-9,18,23-trioxo-2,5,11,14-tetraoxa-8,17,22-triazanonatriacontane-1,21,39-tricarboxylate

tBuO-C18-Glu(AEEA-AEEA-OSu)-OtBu

tBuO-Ste-γGlu(OtBu)-AEEA-AEEA-OSu

tBuO-Ste-rGlu(OtBu)-AEEA-AEEA-OSu

tert-butyl 18-[[(2S)-5-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrolidin-1-yl)oxy-2-oxoethoxy]ethoxy]ethylamino]-2-oxoethoxy]ethoxy]ethylamino]-1-[(2-methylpropan-2-yl)oxy]-1,5-dioxopentan-2-yl]amino]-18-oxooctadecanoate

tBuO-Ste-yGlu(OtBu)-

tBuO-Ste-E(AEEA-AEEA-OSu)-OtBu

tBuO-C18-y-Glu(AEEA-AEEA-OSu)-OtBu

Somalutide side chain

tBuO-C18-γGlu(tBu)-AEEA-AEEA-OSU

Octa(OtBu)-Glu(AEEA-AEEA-OSu)-OtBu

Carbaryl Impurity 1

Semaglutide Impurity 17

Semaglutide Impurity 45

OtBu-C18-Glu(OtBu)-AEEA-AEEA-NHS、tBuO-Ste-Glu(OtBu)-AEEA-AEEA-OSU

tBuO-C18-γ-Glu(AEEA-AEEA-OSu)-OtBu

1118767-15-9

118767-16-0

C47H82N4O15