2-Chloro-1,3-dinitrobenzene Property

Melting point:

86-88°C

Boiling point:

315°C

Density 

1,687 g/cm³

refractive index 

1.5870 (estimate)

Flash point:

315°C

storage temp. 

2-8°C

form 

solid

color 

Pale-yellow to Yellow-brown

Water Solubility 

Soluble in alcohol. Moderately soluble in benzene, ether. Practically insoluble in water.

Merck 

14,2137

BRN 

522187

CAS DataBase Reference

606-21-3(CAS DataBase Reference)

NIST Chemistry Reference

1-Chloro-2,6-dinitrobenzene(606-21-3)

EPA Substance Registry System

2,6-Dinitrochlorobenzene (606-21-3)

Safety

Risk Statements 

23/24/25-33-50/53

Safety Statements 

28-36/37-45-60-61

RIDADR 

3441

RTECS 

CZ0525500

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

II

HS Code 

29049090

Hazardous Substances Data

606-21-3(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H310Fatal in contact with skin

H330Fatal if inhaled

H373May cause damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P320Specific treatment is urgent (see … on this label).

P330Rinse mouth.

P405Store locked up.

2-Chloro-1,3-dinitrobenzene Chemical Properties,Usage,Production

Chemical Properties

Yellow crystals. Soluble in ethanol, ether, and toluene

Uses

The commercial mixture of chlorodinitrobenzenes is used to synthesize other compounds.

Uses

2-Chloro-1,3-dinitrobenzene can be used as intermediates of dyes and pigments. Also used as solvents in HPLC, NMR.

Uses

2,6-Dinitrochlorobenzene (2-Chloro-1,3-dinitrobenzene) is a thiol-modifying agent.

Hazard

Toxic if swallowed. Toxic in contact with skin. Fatal if inhaled. May cause damage to organs through prolonged or repeated exposure. Very toxic to aquatic life with long lasting effects.

Synthesis

The synthesis of 2-Chloro-1,3-dinitrobenzene is as follows:
Add 800ml of sulfolane as solvent to a 2L flask, then add 246.5g of 3,5-dinitro-4-chlorobenzoic acid and 168g of sodium bicarbonate,Heat to 195°C to react for 2h. After the reaction is complete, cool to 130°C and distill under reduced pressure.The product 2-Chloro-1,3-dinitrobenzene, 178.4g, was obtained by rectification with a yield of 88.1%.