Dinitolmide
- Product Name
- Dinitolmide
- CAS No.
- 148-01-6
- Chemical Name
- Dinitolmide
- Synonyms
- d.o.t.;zoamix;ZOALENE;Zoalere;NITROMID;Coccidin;coccidot;Salcostat;coccidinea;dinitolmid
- CBNumber
- CB3427693
- Molecular Formula
- C8H7N3O5
- Formula Weight
- 225.16
- MOL File
- 148-01-6.mol
Dinitolmide Property
- Melting point:
- 170-180 °C (lit.)
- Boiling point:
- 366.66°C (rough estimate)
- Density
- 1.5406 (rough estimate)
- refractive index
- 1.7400 (estimate)
- Flash point:
- 2 °C
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 13.74±0.50(Predicted)
- color
- Pale Beige to Light Beige
- Merck
- 13,3297
- InChI
- InChI=1S/C8H7N3O5/c1-4-6(8(9)12)2-5(10(13)14)3-7(4)11(15)16/h2-3H,1H3,(H2,9,12)
- InChIKey
- ZEFNOZRLAWVAQF-UHFFFAOYSA-N
- SMILES
- C(N)(=O)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1C
- CAS DataBase Reference
- 148-01-6(CAS DataBase Reference)
- EPA Substance Registry System
- Zoalene (148-01-6)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22
- Safety Statements
- 36
- OEB
- B
- OEL
- TWA: 5 mg/m3
- WGK Germany
- 2
- RTECS
- XS4200000
- HS Code
- 29242990
- Hazardous Substances Data
- 148-01-6(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 524417
- Product name
- 3,5-Dinitro-o-toluamide
- Purity
- 98%
- Packaging
- 50g
- Price
- $164
- Updated
- 2025/07/31
- Product number
- 32452
- Product name
- Dinitolmide
- Purity
- VETRANAL , analytical standard
- Packaging
- 25mg
- Price
- $76
- Updated
- 2022/05/15
- Product number
- Z584000
- Product name
- Zoalene
- Packaging
- 25mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- JK527192
- Product name
- 3,5-Dinitro-o-toluamide
- Purity
- 98%
- Packaging
- 10g
- Price
- $36
- Updated
- 2021/12/16
- Product number
- CS-4501
- Product name
- Dinitolmide
- Purity
- 98.77%
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
Dinitolmide Chemical Properties,Usage,Production
Description
Dinitolmide is a yellowish crystalline substance. Molecular weight= 225.18; Freezing/Meltingpoint = 177.2℃. Very slightly soluble in water.
Chemical Properties
Yellowish solid. Very slightly soluble in water; soluble in acetone, acetonitrile, dioxane, and dimethylformamide.
Uses
Dinitolmide may be used as an analytical reference standard for the quantification of the analyte in animal tissues poultry, livestock, and aquatic tissues using chromatography techniques.
Uses
A fodder additive for poultry used to prevent coccidiosis infections. Antiprotozoan drug.
Uses
antiprotozoal
Definition
ChEBI: Dinitolmide is a dinitrotoluene.
General Description
Yellowish, crystalline solid. Mp: 177°C. Very slightly soluble in water. Soluble in acetone, acetonitrile, and dimethylformamide. Used as an anti-parasite drug for poultry. Store in a cool, ventilated place, away from acute fire hazards and easily oxidized materials.
Reactivity Profile
Dinitolmide reacts as an oxidizing agent. Has been known on at least one occasion to explode destructively. Incompatible with easily oxidized materials. Emits toxic NOx fumes if heated to decomposition.
Hazard
Liver damage
Safety Profile
Poison by intravenous route. Moderately toxic by ingestion. Mutation data reported. A strong exothermic reaction above 248OC has caused industrial explosions. When heated to decomposition it emits toxic fumes of NOx. See also NITRO COMPOUNDS of AROMATIC HYDROCARBONS.
Synthesis
39614-85-2
148-01-6
The ammoniation process of step C of the present invention is as follows: 400 L of concentrated ammonia (for ammoniation) and 15 kg of ammonium bicarbonate are added to the reactor, and the pre-prepared acyl chloride solution is slowly added to the reactor under stirring. During the reaction, the reaction temperature was controlled below 40℃ by cooling the brine. After the dropwise addition, the reaction was continued with stirring for 1 to 2 hours. Upon completion of the reaction, a filtration operation was carried out, and the filter cake was washed thoroughly with cold water and subsequently dried to obtain 102.6 kg of 3,5-dinitro-o-methylbenzamide, with a yield of 85.9% (in terms of nitro compounds) and a product purity of 98.5%. In step C of the present invention, an ammonia recovery process was designed to reuse ammonia.
Potential Exposure
AgriculturalChemical; Mutagen. Those involved in the manufacture,formulation, and application of this veterinary coccidiostat,an antiparasite medicine used in poultry.
First aid
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Note to physician: Treat for methemoglobinemia.Spectrophotometry may be required for precise determination of levels of methemoglobinemia in urine
storage
Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with dinitolmide you should be trained on its proper handling and storage. Store in tightly closed containers in a cool, wellventilated area away from alkalies and heat.
Incompatibilities
A weak oxidizing agent, but hightemperatures and pressures may cause violent reactions.Heat can cause a violent exothermic reaction above248℃. Contact with alkalies may form explosive metalsalts.
References
[1] Patent: CN105906523, 2016, A. Location in patent: Paragraph 0037; 0041
[2] Journal of the Society of Chemical Industry, London, 1940, vol. 59, p. 92,94
[3] Journal of the Society of Chemical Industry, London, 1940, vol. 59, p. 92,94
Dinitolmide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Dinitolmide manufacturers
- Product
- Dinitolmide 148-01-6
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2025-03-14
- Product
- dinitolmide 148-01-6
- Price
- US $120.00/KG
- Min. Order
- 1KG
- Purity
- 99.99%
- Supply Ability
- 100KG
- Release date
- 2025-02-25
- Product
- dinitolmide 148-01-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98.00%
- Supply Ability
- 20tons
- Release date
- 2023-09-26