ChemicalBook > CAS DataBase List > L(+)-Gulonic acid gamma-lactone

L(+)-Gulonic acid gamma-lactone

Product Name: L(+)-Gulonic acid gamma-lactone
CAS No.: 1128-23-0
Chemical Name: L(+)-Gulonic acid gamma-lactone
Synonyms: L-GULONOLACTONE;L-GULONO-1,4-LACTONE;L-GULONIC GAMMA-LACTONE;Reduced ascorbate;L-GULONIC-G-LACTONE;GULONOLACTONE(RG) 1g;Reduced Ascorbic Acid;L-GULONO-GAMMA-LACTONE;L(+)-GULONO-1,4-LACTONE;L-GulonicAcid-y-Lactone
CBNumber: CB2341914
Molecular Formula: C6H10O6
Formula Weight: 178.14
MOL File: 1128-23-0.mol

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L(+)-Gulonic acid gamma-lactone Property

Melting point:: 187-190 °C(lit.)
alpha: 54.5 º (c=2, water 57.5 ºC)
Boiling point:: 230.35°C (rough estimate)
Density: 1.3253 (rough estimate)
refractive index: 56 ° (C=2, H2O)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly), Water (Sparingly)
pka: 12.06±0.60(Predicted)
form: Viscous Solution
color: White to Off-white
optical activity: [α]19/D +55°, c = 4 in H2O
Water Solubility: Soluble in water
BRN: 83002
InChI: InChI=1/C6H10O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2-5,7-10H,1H2/t2-,3+,4-,5+/s3
InChIKey: SXZYCXMUPBBULW-QICJDPMJNA-N
SMILES: [C@H]1([C@@H](O)CO)OC(=O)[C@@H](O)[C@H]1O |&1:0,1,8,10,r|
CAS DataBase Reference: 1128-23-0(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
HS Code: 29400090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 310301
Product name: L-Gulonic acid γ-lactone
Purity: 95%
Packaging: 5g
Price: $82.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 310301
Product name: L-Gulonic acid γ-lactone
Purity: 95%
Packaging: 25g
Price: $254
Updated: 2025/07/31

TCI Chemical

Product number: G0235
Product name: L-(+)-Gulonic Acid gamma-Lactone
Purity: >98.0%(GC)
Packaging: 5g
Price: $77
Updated: 2025/07/31

TCI Chemical

Product number: G0235
Product name: L-(+)-Gulonic Acid gamma-Lactone
Purity: >98.0%(GC)
Packaging: 25g
Price: $235
Updated: 2025/07/31

TRC

Product number: G855000
Product name: L-Gulono-1,4-lactone
Packaging: 10g
Price: $90
Updated: 2021/12/16

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L(+)-Gulonic acid gamma-lactone Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

L-Gulono-1,4-lactone is a precursor in the biosynthesis of ascorbic acid, one of the many forms of Vitamin C.

Definition

ChEBI: L-gulono-1,4-lactone is the furanose form of gulonolactone having L-configuration. It has a role as a human metabolite and a mouse metabolite. It is functionally related to a L-gulonic acid.

Synthesis

50-81-7

1128-23-0

The general procedure for the synthesis of L-gulosonic acid-γ-lactone from L-ascorbic acid was as follows: 10% Pd/C catalyst (8.3 g) was added to a solution of L-ascorbic acid (83.9 g, 0.477 mol) in water (600 mL). The reaction mixture was placed in a Parr hydrogenator and hydrogenated for 62 hours at 48 psi hydrogen pressure and 18°C. Upon completion of the reaction, the reaction mixture was filtered to remove the catalyst and the filtrate was concentrated under vacuum to afford L-gulosonic acid-γ-lactone (81.0 g, 96% yield) as an off-white solid. The resulting solid was dried in a vacuum oven at 50 °C for 18 h. The melting point was measured to be 182-184 °C.

References

[1] Journal of Organic Chemistry, 1981, vol. 46, # 14, p. 2976 - 2977
[2] Patent: US2004/54172, 2004, A1
[3] Patent: US2003/232889, 2003, A1. Location in patent: Page/Page column 12
[4] Synlett, 2017, vol. 28, # 8, p. 970 - 972
[5] Tetrahedron Asymmetry, 1996, vol. 7, # 9, p. 2711 - 2720

L(+)-Gulonic acid gamma-lactone Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from L(+)-Gulonic acid gamma-lactone manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: L(+)-Gulonic acid gamma-lactone 1128-23-0
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-13

R&D Scientific Inc.

Product: L-Gulono-1,4-lactone 1128-23-0
Price: US $1290.00/Kg
Min. Order: 0.100Kg
Purity: 99 %
Supply Ability: 5000 Kg
Release date: 2025-06-01

WUHAN FORTUNA CHEMICAL CO., LTD

Product: L(+)-Gulonic acid gamma-lactone 1128-23-0
Price: US $0.00/G
Min. Order: 10G
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-14

1128-23-0, L(+)-Gulonic acid gamma-lactoneRelated Search:

CDH Dodecyl acrylate 4-Hexanolide Polycaprolactone L-GULOSE D-(-)-Gulonic acid gamma-lactone 5,6-O-Isopropylidene-L-gulonic acid-1,4-lactone RARECHEM AL BP 0349 6,3-GLUCURONOLACTONE ACETONIDE D-Glucurono-6,3-lactone acetonide L(+)-Gulonic acid gamma-lactone 2C-Hydroxymethyl-2,3:5,6-di-O-isopropylidene-L-gulono-1,4-lactone 2,3-DI-O-ACETYL-5,6-O-ISOPROPYLIDENE-L-GULONO-1,4-LACTONE 2,3:5,6-Di-O-isopropylidene-L-gulonolactone

L-(+)-GULONIC ACID GAMMA-LACTONE

L-GULONIC ACID GAMMA-LACTONE

L-GULONIC GAMMA-LACTONE

Ascorbic Acid Impurity 16

L-GULONIC-G-LACTONE

L(+)-GULONO-1,4-LACTONE

L-GULONO-1,4-LACTONE

L-GULONO-GAMMA-LACTONE

L-GULONOLACTONE

L-Gulonic acid γ-lactone

L(+)-GULONIC ACID GAMMA-LACTONE 97%

L-GulonicAcid-y-Lactone

L-Gulonicacid-1,4-lactone

(3S,4S,5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-oxolan-2-one

L-(+)-GLUTONIC ACID GAMMA-LACTONE

L-(+)-GLUTONIC ACID -LACTONE

L-GULONO-1,4-LACTONE extrapure

L-Gulonic acid γ-lactone, L-(+)-Gulono-1,4-lactone

(3S)-3β,4β-Dihydroxy-5β-[(S)-1,2-dihydroxyethyl]-4,5-dihydro-2(3H)-furanone

L(+)-Gulonic acid gamma-lactone,97%

L-Gulonic acid-1,4-lactone ,99%

Reduced Ascorbic Acid

L-Gulonic acid, g-lactone

L(+)-Gulonic acid gaMMa-lactone, 95+%

L-Gulonic acid, g-lactone (Dihydroascorbic acid)

(3S,4R,5R)-5-((S)-1,2-dihydroxyethyl)-3,4-dihydroxydihydrofuran-2(3H)-one

L-(+)-GulonicAcidγ-Lactone&gt

L(+)-Gulonic acid gamma-lactone USP/EP/BP

(3S,4R,5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyoxolan-2-one

L-[UL-13C6]gulono-1,4-lactone

Reduced ascorbate

GULONOLACTONE(RG) 1g

L-Gulono-1,4-lactone, 10 mM in DMSO

<sc>L</sc>-Gulonic acid γ-lactone

L-Gulonic acid γ-lactone

1128-23-0

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